Houston health cos. sweep at competition, startups announce new deals, and more innovation news

short stories

Several Houston startups claimed the top prizes at a recent competition — plus more Houston innovation news you may have missed. Photo courtesy of TNVC

It's been a busy season for the Houston innovation ecosystem, and for this reason, local startup and tech news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, a consumer packaged goods startup is now on shelves across Texas, a Texas energy company gets fresh funding from Houston VCs, Texas Medical Center Innovation companies sweep at a recent competition, and more.

Houston health care startups sweep recent competition

Houston-based Starling Medical took home the top prize at a recent competition. Photo courtesy of TNVC

At the 2021 Texas A&M New Ventures Competition, several Houston companies claimed top prizes — essentially sweeping the competition. The top three winners were all member companies of Texas Medical Center Innovation:

  • First Place Finalist: Houston-based Starling Medical – $50,000
  • Second Place Finalist: Houston-based Ictero Medical – $35,000
  • Third Place Finalist: Koda Health – $25,000
Other Houston-area award winners included:
  • Fourth Place Finalist: Microsilicon – $15,000
  • Sixth Place Finalist: CodeWalker – $5,000
  • Elevator Pitch First Place: EmGenysis – $5,000
  • Elevator Pitch Fourth Place: TYBR Health – $1,00
Click here to view more details on the 2021 award results.

Houston CPG company scores Central Market placement

Central Market now carries this Houston startup's baked goods. Photo courtesy of ChipMonk Baking

As of this month, Central Market shoppers in Texas can purchase Houston-based ChipMonk Baking products products. Additionally, the company announced it has added added 1,100 square feet to its existing 2,300 square-foot facility.

Founded by David Downing and Jose Hernandez, ChipMonk Baking, is a local, mail-order bakery that makes cookies, brownie bites, and other snacks using monk fruit and allulose, a low-calorie (0.4 calories per gram) rare sugar that's found naturally in foods such as raisins, dried figs, and kiwi.

The nine open Central Market locations throughout Texas will carry all nine flavors of ChipMonk's Keto Cookie Bites.

"Here in Houston, ChipMonk is the healthy option — there is nothing else like our products being made in a city that's known around the world for food," says Downing in a press release. "When you consider Houston's diversity and international culinary reputation, the lack of local health-food representation and production just doesn't make sense. We love this city and are working to change that."

Houston Methodist doles out $2.5 million in grants

Houston Methodist has contributed a couple million dollars to Houston nonprofits. Courtesy of Methodist Hospital/Facebook

Houston Methodist announced a couple weeks ago that it has awarded nearly $2.5 million in community grant investment to 37 Houston-area nonprofit organizations, according to a news release from the health care organization.

Over 177 Houston nonprofits applied for the Houston Methodist Diversity, Equity & Inclusion Grant Program, a program created last year to address the social determinants of health that lead to health inequities within racial, ethnic and social minorities.

"We continuously strive to build and maintain a diverse, equitable and inclusive environment both within our hospital walls and within our communities," says Arianne Dowdell, vice-president, chief diversity, equity and inclusion officer at Houston Methodist, in the release. "The grant program and all the deserving organizations awarded funds are critical in shaping our community, which Houston Methodist has proudly supported for decades. We look forward to fostering the growth and development of meaningful programs that will benefit underserved and underrepresented groups in Houston."

The program, which includes both DEI Grants and Social Equity Grants, is funded by a $25 million fund established by Houston Methodist to be doled out over five years to support underserved communities.

Innovative energy company receives funding from Houston venture capital

Houston-based Cottonwood Venture Partners and Chevron Technology Ventures have again invested in this Austin-area energy company. Photo courtesy of Getty Images

Two Houston venture capital groups recently went in on Round Rock, Texas-based Infinitum Electric's $40 million series C funding round. Houston-based Cottonwood Technology Fund and Chevron Technology Ventures — both existing investors for the company — doubled down on their support in the new round led by San Francisco-based Energy Innovation Capital.

The fresh funds will allow the company to scale production of its ultra-high-efficiency, lightweight motors and "expand production of the company's IEs Series motors for commercial and industrial applications and complete development of its IEm Series motors for the rapidly growing electric vehicle market," according to the company's news release.

"We're excited to ramp production of our motors after seeing significant demand in the commercial HVAC and industrial markets, as well as the growing interest from electric vehicle suppliers who see the potential a highly efficient, lightweight motor can deliver," says Ben Schuler, founder and CEO of Infinitum Electric, in the news release. "Partnering with Energy Innovation Capital, Rockwell Automation and our existing investors allows us to scale and power machines more efficiently and sustainably."

Houston nanotechnology startup scores distribution deal

Houston-based NanoTech, currently housed in Halliburton Labs, has a new distribution agreement. Photo via halliburtonlabs.com

NanoTech has announced a new distribution agreement with Warrior Ace Hardware, a supplier of specialty products for the commercial and residential building industries. NanoTech uses material science to create NanoShield, a fire-proofing and insulation product.

The new partnership offers a key opportunity for NanoTech, which recently closed a $5 million round of funding.

"Ace Hardware has close to 100 years of distribution and retail experience. We are excited to partner with such a respected brand to get us one step closer to saving a tremendous amount of lives, protecting infrastructure, and reducing energy consumption," says Mike Francis, CEO of NanoTech in a news release.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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