Houston health cos. sweep at competition, startups announce new deals, and more innovation news

short stories

Several Houston startups claimed the top prizes at a recent competition — plus more Houston innovation news you may have missed. Photo courtesy of TNVC

It's been a busy season for the Houston innovation ecosystem, and for this reason, local startup and tech news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, a consumer packaged goods startup is now on shelves across Texas, a Texas energy company gets fresh funding from Houston VCs, Texas Medical Center Innovation companies sweep at a recent competition, and more.

Houston health care startups sweep recent competition

Houston-based Starling Medical took home the top prize at a recent competition. Photo courtesy of TNVC

At the 2021 Texas A&M New Ventures Competition, several Houston companies claimed top prizes — essentially sweeping the competition. The top three winners were all member companies of Texas Medical Center Innovation:

  • First Place Finalist: Houston-based Starling Medical – $50,000
  • Second Place Finalist: Houston-based Ictero Medical – $35,000
  • Third Place Finalist: Koda Health – $25,000
Other Houston-area award winners included:
  • Fourth Place Finalist: Microsilicon – $15,000
  • Sixth Place Finalist: CodeWalker – $5,000
  • Elevator Pitch First Place: EmGenysis – $5,000
  • Elevator Pitch Fourth Place: TYBR Health – $1,00
Click here to view more details on the 2021 award results.

Houston CPG company scores Central Market placement

Central Market now carries this Houston startup's baked goods. Photo courtesy of ChipMonk Baking

As of this month, Central Market shoppers in Texas can purchase Houston-based ChipMonk Baking products products. Additionally, the company announced it has added added 1,100 square feet to its existing 2,300 square-foot facility.

Founded by David Downing and Jose Hernandez, ChipMonk Baking, is a local, mail-order bakery that makes cookies, brownie bites, and other snacks using monk fruit and allulose, a low-calorie (0.4 calories per gram) rare sugar that's found naturally in foods such as raisins, dried figs, and kiwi.

The nine open Central Market locations throughout Texas will carry all nine flavors of ChipMonk's Keto Cookie Bites.

"Here in Houston, ChipMonk is the healthy option — there is nothing else like our products being made in a city that's known around the world for food," says Downing in a press release. "When you consider Houston's diversity and international culinary reputation, the lack of local health-food representation and production just doesn't make sense. We love this city and are working to change that."

Houston Methodist doles out $2.5 million in grants

Houston Methodist has contributed a couple million dollars to Houston nonprofits. Courtesy of Methodist Hospital/Facebook

Houston Methodist announced a couple weeks ago that it has awarded nearly $2.5 million in community grant investment to 37 Houston-area nonprofit organizations, according to a news release from the health care organization.

Over 177 Houston nonprofits applied for the Houston Methodist Diversity, Equity & Inclusion Grant Program, a program created last year to address the social determinants of health that lead to health inequities within racial, ethnic and social minorities.

"We continuously strive to build and maintain a diverse, equitable and inclusive environment both within our hospital walls and within our communities," says Arianne Dowdell, vice-president, chief diversity, equity and inclusion officer at Houston Methodist, in the release. "The grant program and all the deserving organizations awarded funds are critical in shaping our community, which Houston Methodist has proudly supported for decades. We look forward to fostering the growth and development of meaningful programs that will benefit underserved and underrepresented groups in Houston."

The program, which includes both DEI Grants and Social Equity Grants, is funded by a $25 million fund established by Houston Methodist to be doled out over five years to support underserved communities.

Innovative energy company receives funding from Houston venture capital

Houston-based Cottonwood Venture Partners and Chevron Technology Ventures have again invested in this Austin-area energy company. Photo courtesy of Getty Images

Two Houston venture capital groups recently went in on Round Rock, Texas-based Infinitum Electric's $40 million series C funding round. Houston-based Cottonwood Technology Fund and Chevron Technology Ventures — both existing investors for the company — doubled down on their support in the new round led by San Francisco-based Energy Innovation Capital.

The fresh funds will allow the company to scale production of its ultra-high-efficiency, lightweight motors and "expand production of the company's IEs Series motors for commercial and industrial applications and complete development of its IEm Series motors for the rapidly growing electric vehicle market," according to the company's news release.

"We're excited to ramp production of our motors after seeing significant demand in the commercial HVAC and industrial markets, as well as the growing interest from electric vehicle suppliers who see the potential a highly efficient, lightweight motor can deliver," says Ben Schuler, founder and CEO of Infinitum Electric, in the news release. "Partnering with Energy Innovation Capital, Rockwell Automation and our existing investors allows us to scale and power machines more efficiently and sustainably."

Houston nanotechnology startup scores distribution deal

Houston-based NanoTech, currently housed in Halliburton Labs, has a new distribution agreement. Photo via halliburtonlabs.com

NanoTech has announced a new distribution agreement with Warrior Ace Hardware, a supplier of specialty products for the commercial and residential building industries. NanoTech uses material science to create NanoShield, a fire-proofing and insulation product.

The new partnership offers a key opportunity for NanoTech, which recently closed a $5 million round of funding.

"Ace Hardware has close to 100 years of distribution and retail experience. We are excited to partner with such a respected brand to get us one step closer to saving a tremendous amount of lives, protecting infrastructure, and reducing energy consumption," says Mike Francis, CEO of NanoTech in a news release.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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