The Texas Space Commission has selected Houston's Intuitive Machines to develop a vehicle that will return lunar samples to Earth, along with an orbital fabrication lab. Photo courtesy Intuitive Machines.

Houston-based space technology, infrastructure, and services company Intuitive Machines has been awarded a state grant of up to $10 million to help develop an Earth re-entry vehicle and in-space biomanufacturing lab.

The Texas Space Commission approved the grant, which is coming from the state’s Space Exploration and Research Fund.

Intuitive Machines says the money will support its “critical risk-reduction platform” for returning lunar samples to Earth. The funding will go toward an early 12-month phase of the project.

“Returning samples from space is one of the most complex challenges in exploration,” says Tim Crain, chief growth officer at Intuitive Machines.

In 2022, Intuitive Machines began preliminary design work on an Earth re-entry vehicle for missions returning from low Earth orbit, the moon, or Mars. In tandem with development of the re-entry vehicle, the company has teamed up with Houston-based biotech company Rhodium Scientific on in-space biomanufacturing. This biomanufacturing will involve certain materials, processes and pharmaceuticals that can be handled more efficiently in space or that exhibit unique non-Earth properties.

Gámez Holzhaus, founder and CEO of Rhodium Scientific, says his company’s federally backed work “has enabled us to establish all hardware and protocols necessary for a pipeline to develop and scale biomanufacturing in space.”

Intuitive Machines and Rhodium Scientific say the state grant should pave the way for future grants and large-scale projects to bring the re-entry system closer to flight readiness.

Tim Crain explains Intuitive Machines' mission to develop tech for the moon on the Houston Innovators Podcast. Photo via intuitivemachines.com

Play it back: This Houston innovator is on a mission to develop tech for the moon

HOUSTON INNOVATORS PODCAST EPISODE 244

Editor's note: This week on the Houston Innovators Podcast, we’re revisiting a conversation with Tim Crain, the co-founder and CTO at Intuitive Machines, that originally ran in October of 2023.

If you haven't noticed, the moon is having a bit of a moment — and Tim Crain of Intuitive Machines is here for it.

For the past five or so years, NASA and the federal government have introduced and strengthened initiatives to support innovation of technology to be used to get to and explore the moon.

NASA, which is currently focused on its Artemis program that's sending four missions to the moon, also launched the Commercial Lunar Payload Services that's working with several American companies, including Intuitive Machines, to deliver science and technology to the lunar surface.

"Around 2018 or 2019, the moon came back into favor as a destination for American space policy, and it came back in such a way that there's a directive at the national level — at a level above NASA — to explore and develop the moon as a national priority," Crain says in the episode.



On the show, Crain explains the history of Intuitive Machines, which has taken an indirect path to where it is today. The company was founded in 2013 by Crain and co-founders CEO Steve Altemus and Chairman Kamal Ghaffarian as a space-focused think tank. Crain says they learned how to run a business and meet customers' needs and expectations, but they never fell in love with any of the early technologies and ideas they developed — from long-range drones to precision drilling technologies.

But the company answered NASA's call for moon technology development, and Intuitive Machines won three of the NASA contracts so far, representing three missions for NASA.

"We dipped our toe in the 'let's develop the moon' river and promptly got pulled all the way in," Crain says. "We left our think tank, broad, multi-sector efforts behind, and really pivoted at that point to focus entirely on NASA's CLPS needs. ... The timing really could not have been any better."

Since recording the podcast, Intuitive Machines celebrated a historic mission that landed the first lunar lander on the surface of the moon in over 50 years — and the first commercially operated mission ever. The company is also working on a $30 million project for NASA to develop lunar lander technology.

This week, Intuitive Machines announced a successful test result for engine technology to be used in the lunar lander project.

While originally thought to be successful, Intuitive Machines' lunar landing has gone askew. Here's what's known so far, and the impact it could have on future missions. Photo courtesy of NASA

Houston-based lunar mission's rocky landing and what it means for America's return to the moon

houston, we have a problem

A private U.S. lunar lander tipped over at touchdown and ended up on its side near the moon’s south pole, hampering communications, company officials said Friday.

Intuitive Machines initially believed its six-footed lander, Odysseus, was upright after Thursday's touchdown. But CEO Steve Altemus said Friday the craft “caught a foot in the surface," falling onto its side and, quite possibly, leaning against a rock. He said it was coming in too fast and may have snapped a leg.

“So far, we have quite a bit of operational capability even though we’re tipped over," he told reporters.

But some antennas were pointed toward the surface, limiting flight controllers' ability to get data down, Altemus said. The antennas were stationed high on the 14-foot (4.3-meter) lander to facilitate communications at the hilly, cratered and shadowed south polar region.

Odysseus — the first U.S. lander in more than 50 years — is thought to be within a few miles (kilometers) of its intended landing site near the Malapert A crater, less than 200 miles (300 kilometers) from the south pole. NASA, the main customer, wanted to get as close as possible to the pole to scout out the area before astronauts show up later this decade.

NASA's Lunar Reconnaissance Orbiter will attempt to pinpoint the lander's location, as it flies overhead this weekend.

With Thursday’s touchdown, Intuitive Machines became the first private business to pull off a moon landing, a feat previously achieved by only five countries. Japan was the latest country to score a landing, but its lander also ended up on its side last month.

Odysseus' mission was sponsored in large part by NASA, whose experiments were on board. NASA paid $118 million for the delivery under a program meant to jump-start the lunar economy.

One of the NASA experiments was pressed into service when the lander's navigation system did not kick in. Intuitive Machines caught the problem in advance when it tried to use its lasers to improve the lander's orbit. Otherwise, flight controllers would not have discovered the failure until it was too late, just five minutes before touchdown.

“Serendipity is absolutely the right word,” mission director Tim Crain said.

It turns out that a switch was not flipped before flight, preventing the system's activation in space.

Launched last week from Florida, Odysseus took an extra lap around the moon Thursday to allow time for the last-minute switch to NASA's laser system, which saved the day, officials noted.

Another experiment, a cube with four cameras, was supposed to pop off 30 seconds before touchdown to capture pictures of Odysseus’ landing. But Embry-Riddle Aeronautical University’s EagleCam was deliberately powered off during the final descent because of the navigation switch and stayed attached to the lander.

Embry-Riddle's Troy Henderson said his team will try to release EagleCam in the coming days, so it can photograph the lander from roughly 26 feet (8 meters) away.

"Getting that final picture of the lander on the surface is still an incredibly important task for us,” Henderson told The Associated Press.

Intuitive Machines anticipates just another week of operations on the moon for the solar-powered lander — nine or 10 days at most — before lunar nightfall hits.

The company was the second business to aim for the moon under NASA's commercial lunar services program. Last month, Pittsburgh's Astrobotic Technology gave it a shot, but a fuel leak on the lander cut the mission short and the craft ended up crashing back to Earth.

Until Thursday, the U.S. had not landed on the moon since Apollo 17's Gene Cernan and Harrison Schmitt closed out NASA's famed moon-landing program in December 1972. NASA's new effort to return astronauts to the moon is named Artemis after Apollo's mythological twin sister. The first Artemis crew landing is planned for 2026 at the earliest.

This week's roundup of Houston innovators includes Tim Crain of Intuitive Machines, Chelsea Williams of Northwestern Mutual, and Nicolaus Radford of Nauticus Robotics. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space tech to robotics — recently making headlines in Houston innovation.

Tim Crain, co-founder and CTO of Intuitive Machines

Tim Crain joins the Houston Innovators Podcast. Photo via intuitivemachines.com

It might surprise many to learn that publicly traded, NASA-backed Intuitive Machines, which has emerged as a commercial leader within lunar access technology development, had several pivots before finding its niche within space innovation.

In fact, as Co-Founder and CTO Tim Crain explains on this week's episode of the Houston Innovators Podcast, the company was founded as a space-focused think tank. Crain, along with his co-founders CEO Steve Altemus and Chairman Kamal Ghaffarian, came together in 2013 to start Intuitive Machines, which recently moved into a $40 million headquarters in the Houston Spaceport.

"At the time, our thought was, 'let's take the best of human space flight engineering processes, disciplines, and know how, and look at how we might commercially deploy that for biomedical, energy, big data, and aerospace,'" Crain says on the show. "We wanted to look at how we use great engineering for some of the hard problems outside of NASA's aerospace sphere." Read more.

Chelsea Williams, financial adviser at Northwestern Mutual

Houston-based financial adviser Chelsea Williams helps clients overcome their unique generational financial uncertainties by equipping them with tips and resources to get them on the path to financial wellness. Photo courtesy

In a guest column for InnovationMap, Chelsea Williams, financial adviser at Northwestern Mutual, shared tips on overcoming financial uncertainty across different generations.

"While the types of financial stressors might vary across generations and cities, the most important step to managing financial uncertainty is initiating a conversation with an adviser," she writes in her column. "Just like going to the doctor regularly, routine financial check-ups are incredibly important to catch financial headaches early on and stay ahead of long-term financial health." Read more.

Nicolaus Radford, founder and CEO of Nauticus Robotics

Houston-based Nauticus Robotics founder, Nicolaus Radford, celebrated an acquisition for his company. Image via LinkedIn

A Houston company that harnesses the power of robotics hardware and programing for underwater use has made an acquisition.

Nauticus Robotics Inc. (NASDAQ: KITT) announced it has acquired 3D at Depth Inc., a Colorado-based company with a subsea light detection and range, LiDAR, technology for inspection and data services. The deal closed for approximately $34 million in stock, before certain purchase price adjustments and the assumption of debt, per the news release.

“The future of subsea services lies in autonomy, data gathering, and analytics,” Nicolaus Radford, Nauticus’ founder and CEO, says in the release. “LiDAR has long since been core to terrestrial autonomy and by adding 3D’s capabilities to the Nauticus Fleet, we enhance autonomous vehicles in the offshore market. This acquisition increases the value of Nauticus’ fleet services and positions the Company to capitalize on data acquisition and analytics for subsea operations.” Read more.

Tim Craine is co-founder and CTO of Intuitive Machines. Photo via intuitivemachines.com

Houston innovator discusses the power of a pivot and the future of the Space City

houston innovators podcast episode 208

It might surprise many to learn that publicly traded, NASA-backed Intuitive Machines, which has emerged as a commercial leader within lunar access technology development, had several pivots before finding its niche within space innovation.

In fact, as Co-Founder and CTO Tim Crain explains on this week's episode of the Houston Innovators Podcast, the company was founded as a space-focused think tank. Crain, along with his co-founders CEO Steve Altemus and Chairman Kamal Ghaffarian, came together in 2013 to start Intuitive Machines, which recently moved into a $40 million headquarters in the Houston Spaceport.

"At the time, our thought was, 'let's take the best of human space flight engineering processes, disciplines, and know how, and look at how we might commercially deploy that for biomedical, energy, big data, and aerospace,'" Crain says on the show. "We wanted to look at how we use great engineering for some of the hard problems outside of NASA's aerospace sphere."

Crain describes the early years of IM as important to the company because the founders learned how to run a business and meet customers' needs and expectations — things he had little experience from his previous roles as a civil servant at NASA. But Crain says they never fell in love with any of the early technologies and ideas they developed — from long-range drones to precision drilling technologies.

Then, everyone's eyes were on returning to the moon. With this new vision, NASA created the Commercial Lunar Payload Services Program. As Crain explains, this evolution involved looking to hire companies to deliver scientific and developmental payloads to the moon. IM won three of the NASA contracts so far, representing three missions for NASA.

"We dipped our toe in the 'let's develop the moon' river and promptly got pulled all the way in," Crain says. "We left our think tank, broad, multi-sector efforts behind, and really pivoted at that point to focus entirely on NASA's CLPS needs. ... The timing really could not have been any better."

Later this month, Crain will discuss IM's journey in detail for a NASA Tech Talk at the Ion. If you're interested in learning more after listening to the podcast, click here to sign up for the free October 26 event.

With Crain's decades in the space industry, he's observed a resurgence lately, and that has directly impacted Houston's role in the industry.

"The future of Space City is really just beginning to move into a time of producing the hardware here and having Houstonians make the spacecraft, space systems, and the technologies that we use to explore and develop the solar system," Crain says on the show.

Houston's primed to lead space innovation into the future — it's already happening here, as one panel at SXSW explains. Image via axiomspace.com

Houston experts at SXSW: Why now is the opportune time for space commercialization

Houston House

For all of the time they've been on earth, humans have looked up and wondered what was out there. Now more than ever, as a recent panel of experts discussed, humans are equipped to find out.

“We actually have, for the very first time, not just the ability to answer those questions, but to be able to go and live among the stars,” says Douglas Terrier, associate director for vision and strategy at NASA's Johnson Space Center. “It’s really a phenomenal thing to think that we are existing at this time.”

Terrier was joined by fellow panelists Matt Ondler, CTO of Axiom Space, and Tim Crain, CTO of Intuitive Machines, along with moderator Arturo Machuca, director of Houston Spaceport, to explore what has contributed to this unique moment in time for space commercialization. The panel, which was presented by Houston Spaceport and hosted by the Greater Houston Partnership, took place at Houston House at SXSW on Sunday, March 13.

An industry that was run exclusively by the government has evolved to include commercialization — and not just on a corporate level.

“We’re at this inflection point where access to space is easier — companies are emerging and it’s not just NASA and big companies like Boeing and Lockheed that can participate in space,” Ondler says.

This evolution was crucial to continue developing the technologies needed to advance the industry. Ondler's company Axiom Space is working on the first commercial space station for lower earth orbit, or LEO. This project will be 100 to 1,000 times less expensive than what it cost to build the International Space Station.

“We’re really leveraging so much history and so much of the government’s investment to build our commercial space station,” Ondler says.

The LEO economy is a trillion dollar economy — and one that has been overtaken by commercial companies, which is exactly what NASA needed to allow for it to refocus efforts to returning to the moon with its Artemis project.

“We’ve gotten over that first obstacle where we’ve commercialized operations of low earth orbit,” Terrier says. “That frees us up to look further.”

For decades, the aerospace industry has been responsible for churning out technologies that, in addition to their space application, can make a difference on earth as well.

“We spend a lot of money getting to space, but what it does is push forward all of these things we have to invent, and they find their ways into application in medicine, water purification, clean energy — all return tenfold value to our society," Terrier says on the panel.

Today, Terrier says the space economy is over $400 billion — and only a quarter of that is government investment. With this influx of companies working in space innovation, Houston has all it needs to be a leader in the field.

“Innovation and the ability to commercially engage in space requires a lot of ideas and new ways of looking of things,” Crain says, pointing out the area around the JSC and the spaceport. “The more opportunities we have for these ideas to come together and interchange, that is going to open up the capability to make commercialization successful.”

He continues saying the city is building a critical mass with space tech startups, talent within engineering and manufacturing, government support, and more.

“It’s more open now than it's ever been for both the city and for NASA to support companies who want to work in Houston,” Crain says. “When you put all those ingredients together the opportunities are really endless, and it’s the place to be.”

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Houston professor awarded $2.6M grant for retina, neurological research

seeing green

University of Houston College of Optometry Professor John O’Brien has received a $2.6 million grant from the National Eye Institute to continue his research on the retina and neurological functions.

O’Brien is considered a leading expert in retinal neuroscience with more than 20 years of research in the field. The new funding will allow O’Brien and his team to continue to study the dense assembly of proteins associated with electrical synapses, or gap junctions, in the retina.

Gap junctions transfer electrical signals between neurons. And the plasticity of gap junctions changes the strength of a synapse, in turn changing how visual information is processed. Previous research has shown that reduced functions of electrical synapses could be linked to autism, while their hyperfunction may lead to seizures.

“The research we propose will significantly advance our understanding of the molecular complexes that control the function of electrical synapses,” O’Brien said in a news release.

The team at UH will work to identify the proteins and examine how they impact electrical synapses. It is particularly interested in the Connexin 36, or Cx36, protein. According to O’Brien, phosphorylation of Cx36, a short-term chemical modification of the protein, serves as a key driver of plasticity. And the protein has been linked to refractive error development, which is one of the largest vision problems in the world today.

Additionally, OBrien’s research has shown that plasticity is essential for all-day vision, allowing the retina to adjust sensitivity and sharpen images. He has also built a catalog of the core set of proteins surrounding electrical synapses that are conserved across species. His research has been funded by the NEI since 2000.

5 minority-founded Houston startups shine as Innovation Awards finalists

Meet the Finalists

Houston is one of the most diverse cities in the nation, and that trend carries over into its innovation and startup ecosystem.

As part of the 2025 Houston Innovation Awards, our Minority-founded Businesses category will honor an innovative Houston startup founded or co-founded by BIPOC or LGBTQ+ representation.

Five minority-founded businesses have been named finalists for the 2025 award. The finalists, selected by our esteemed panel of judges, range from a wearable health tech device company to a clean chemical manufacturing business to a startup with a lunar mission.

Read more about these innovative businesses, their initiatives, and their inspirational founders below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are on now for this exclusive event celebrating all things Houston Innovation.

Capwell Services

Houston-based methane capture company Capwell Services works to eliminate vented oil and gas emissions economically for operators. According to the company, methane emissions are vented from most oil and gas facilities due to safety protocols, and operators are not able to capture the gas cost-effectively, leading operators to emit more than 14 million metric tons of methane per year in the US and Canada, equivalent to more than 400 million metric tons of CO2e per year. Founded in 2022, Capwell specializes in low and intermittent flow vents for methane capture.

The company began as a University of Pennsylvania senior design project led by current CEO Andrew Lane. It has since participated in programs with Greentown Labs and Rice Clean Energy Accelerator. The company moved to Houston in 2023 and raised a pre-seed round. It has also received federal funding from the DOE. Capwell is currently piloting its commercial unit with oil and gas operators.

Deep Anchor Solutions

Offshore energy consulting and design company Deep Anchor Solutions aims to help expedite the adoption of floating offshore energy infrastructure with its deeply embedded ring anchor (DERA) technology. According to the company, its patented DERA system can be installed quietly without heavy-lift vessels, reducing anchor-related costs by up to 75 percent and lifecycle CO2 emissions by up to 80 percent.

The company was founded in 2023 by current CEO Junho Lee and CTO Charles Aubeny. Lee earned his Ph.D. in geotechnical engineering from Texas A&M University, where Aubeny is a professor of civil and environmental engineering. The company has not raised VC funding, but has participated in numerous accelerators and incubators, including Greentown Labs, MassChallenge, EnergyTechNexus LiftOff and others. Lee is an Activate 2025 fellow.

Mars Materials

Clean chemical manufacturing business Mars Materials is working to convert captured carbon into resources, such as carbon fiber and wastewater treatment chemicals. The company develops and produces its drop-in chemical products in Houston and uses an in-licensed process for the National Renewable Energy Lab to produce acrylonitrile, which is used to produce plastics, synthetic fibers and rubbers. The company reports that it plans to open its first commercial plant in the next 18 months.

Founded in 2019 by CEO Aaron Fitzgerald, CTO Kristian Gubsch and lead engineer Trey Sheridan, the company has raised just under $1 million in capital and is backed by Bill Gates’ Breakthrough Energy, Shell, Black & Veatch and other organizations.

Torres Orbital Mining (TOM)

Space tech company Torres Orbital Mining aims to pioneer the sustainable extraction and processing of lunar regolith and designs and builds robotic systems for excavating, classifying, and delivering lunar material. The company aims to accelerate a permanent and ethical human presence on the Moon.

The company was founded this year by Luis Torres, a current MBA candidate at Rice Business.

Wellysis USA Inc.

Wellysis USA Inc. works to detect heart rhythm disorders with its continuous ECG/EKG monitor with AI reporting. Its S-Patch cardiac monitor is designed for extended testing periods of up to 14 days on a single battery charge. The device weighs only 9 grams, is waterproof and designed to be comfortable to wear, and is considered to have a high detection rate for arrhythmias. It is ideally suited for patient-centric clinical trials to help physicians make diagnoses faster, cheaper and more conveniently.

It was established in Houston in 2023 and participated in the JLABS SFF Program the same year. It closed a $12 million series B last year. It was founded by CEO Young Juhn, CTO Rick Kim, CFO JungSoo Kim and chief strategy officer JoongWoo Kim.

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The Ion taps John Reale for startup and investor role

new hire

The Ion has named John "JR" Reale as its director for startups and investor engagement.

In his new role, Reale, a longtime leader in Houston’s startup ecosystem, will work to strengthen the innovation district's founder and investor network.

"Here’s what I’ve come to believe: the Ion is not just a building, not just a real estate play, and not just another innovation district. COVID, remote work, and shifting market dynamics changed the rules. Key ingredients like co-working, events, and community, while impactful, are no longer enough on their own," Reale shared on a LinkedIn post announcing the move. "What’s needed are advantages ... We need to intentionally design a system that repeatedly delivers advantages so founders can pull forward their visions."

Reale previously served as executive in residence and venture partner at TMC Venture Fund and co-founded Station Houston. He also serves as managing director of Integr8d Capital. He's an investor and serves on the board of directors for a number of venture-backed companies, including Cart.com, Lionguard and others.

The Ion will host "Today Is Day One – A conversation with John (JR) Reale" to welcome Reale to the role on Tuesday, Oct. 21. Reale will be joined at the event by Heath Butler, partner at Mercury, to discuss their thoughts on shaping Houston's founders ecosystem, as well as the Ion’s Founder Advantage Platform.

"On top of this connected architecture, we will build product. That product will be the Founder Advantage Platform to remove friction, compress time, and compound outcomes," Reale continued on LinkedIn. "This is the system that will drive repeatable experiences, and naturally, make these journeys so much more fun."