These two Houston software companies are making contracts less cumbersome for oil and gas companies

Team work

James Yockey is a co-founder of Landdox, which recently integrated with ThoughtTrace. Courtesy of Landdox

The biggest asset of most oil and gas companies is their leasehold: the contracts or deeds that give the company the right to either drill wells and produce oil and gas on someone else's land, or give them title to that land outright. A typical oil and gas company is involved in thousands of these uniquely negotiated leases, and the software to keep these documents organized hasn't been updated in more than a decade, says James Yockey, founder of Houston-based Landdox.

Landdox does just that: provides an organizational framework for companies' contracts and leaseholds. The company recently entered into an integration with Houston-based ThoughtTrace, an artificial intelligence program that can scan and pull out key words and provisions from cumbersome, complicated contracts and leaseholds.

With this integration, companies can use ThoughtTrace to easily identify key provisions of their contracts, and then sync up those provisions with their Landdox account. From there, Landdox will organize those provisions into easy-to-use tools like calendars, reminders and more.

The framework behind the integration
The concept behind Landdox isn't entirely new — there are other software platforms built to organize oil and gas company's assets — but it's the first company in this space that's completely cloud-based, Yockey says.

"Within these oil and gas leases and other contracts are really sticky provisions … if you don't understand them, and you're not managing them, it can cause you to forfeit a huge part of your asset base," Yockey says. "It can be a seven-, eight-, or nine-digit loss."

These contracts and leases can be as long as 70 or 80 pages, Yockey says, and have tricky provisions buried in them. Before the integration with ThoughtTrace, oil and gas companies would still have to manually pour over these contracts and identify key provisions that could then be sent over to Landdox, which would organize the data and documents in an easy-to-use platform. The ThoughtTrace integration removes a time-consuming aspect of the process for oil and gas companies.

"[ThoughtTrace] identifies the most needle moving provisions and obligations and terms that get embedded in these contracts by mineral owners," Yockey says. "It's a real source of leverage for the oil and gas companies. You can feed ThoughtTrace the PDF of the lease and their software will show you were these provisions are buried."

The origin story
Landdox was founded in 2015, and is backed by a small group of angel investors. Yockey says the investors provided a "little backing," and added that Landdox is a "very capital-efficient" software company.

Landdox and ThoughtTrace connected in 2017, when the companies were working with a large, private oil and gas company in Austin. The Austin-based oil and gas company opted to use Landdox and ThoughtTrace in parallel, which inspired the two companies to develop an integrated prototype.

"We built a prototype, but it was clear that there was a bigger opportunity to make this even easier," Yockey says. "To quote the CEO of ThoughtTrace, he called [the integration] an 'easy button.'"

The future of ERP software
Landdox's average customer is a private equity-backed E&P or mineral fund, Yockey says, thought the company also works with closely held, family-owned companies. Recently, though, Landdox has been adding a new kind of company to its client base.

"What's interesting is we're starting to add a new customer persona," Yockey says. "The bigger companies – the publicly traded oil and gas companies –have all kinds of different ERP (Enterprise Resource Planning) software running their business, but leave a lot to be desired in terms of what their team really needs."

At a recent North American Prospect Expo summit, Yockey says that half a dozen large capitalization oil and gas producers invited Landdox to their offices, to discuss potentially supplementing the company's ERP software.

"Instead of trying to be all things to all people, we stay in our lane, but find cool ways to connect with other software (companies)," Yockey says.

Greenway Plaza, which has recently renovated to introduce new spaces like The Hub, has a few more tech companies calling the office park home. Courtesy of Parkway Property Investments

3 tech companies ink deals in Greenway Plaza

Moving in

Three technology companies have executed new leases in Greenway Plaza. The leases represent over 20,000 square feet of space.

One of the companies has already moved in to the 52-acre Greenway Plaza, which is managed by Parkway Property Investments, LLC., while the others have move-in dates throughout the year.

"With renovations at Greenway 8 and 12 now complete, we're seeing broad-based interest from a variety of sectors drawn to an engaging, multi-faceted environment centered around convenience and collaboration with easy ingress and egress, a pedestrian-oriented layout, plus extensive and growing campus amenities such as the upcoming 80,000-square-foot Life Time Athletic club," says Parkway's COO, Mike Fransen, in a release.

Houston-based ThoughtTrace, Inc. is expected to move into its 4,358-square-foot space in Phoenix Tower the first quarter of 2019. The software-as-a-service startup uses artificial intelligence to make data entry and other tasks more efficient for oil and gas companies. The office will be the company's headquarters, and has regional sales offices in Dallas/Fort Worth, Denver, Oklahoma City, and Pennsylvania. Allie Hubbard, Brandi McDonald, and Christina Ott with Limestone Commercial brokered the deal on behalf of ThoughtTrace, while Rima Soroka and JP Hutcheson represented Parkway.

DMC, Inc., based in Chicago, is moving its Houston office from the Upper Kirby area to Greenway Plaza. The cross-industry software and engineering services company plans to set up 6,403-square-foot space in 8 Greenway Plaza in the third quarter of this year. DMC was represented by William Padon of CBRE and Parkway by Rima Soroka and JP Hutcheson.

Industrial Internet of Things platform, Detechtion Technologies, relocated its headquarters last month to a 12,000-square-foot space at 8 Greenway Plaza. Amanda Nebel and Eric Siegrist represented Parkway in the deal, while Detechtion Technologies was represented by Joshua Brown and Evan Roland of Newmark Knight Frank.

In addition to the three new tenants, the office park saw a few lease renewals from tech tenants including 30,000 square feet of new leases for NextSeed, Joule Processing, SkillGigs, and Marker Therapeutics, as well as an 8,000-square-foot renewal by a commercial operations enterprise software provider, according to the release.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

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