Grace Rodriguez, CEO and executive director of Impact Hub Houston, has a few weeks ahead of her. Courtesy of Grace Rodriguez

Impact Hub Houston — the local chapter of a nonprofit focused on supporting startups in the social impact space — has a lot on its plate this month.

Not only is next week The Houston Innovation Summit — the fourth annual week of entrepreneurship programming — as well as the second annual Climathon, but the organization has also just launched a new business incubator program.

Accelerate is a program that Impact Hub has offered across 17 international markets. Houston's new chapter already has a few Houston startups involved — including Potentia Workforce and McMac CX. Structured as an ongoing accelerator with mentorship, education, and support, the program is currently accepting new members.

"We actually sit down with each new Accelerate member and then go through a diagnostic interview to help them understand what stage they're at," says Grace Rodriquez, CEO and executive director of Houston Impact Hub. "And then we create a development strategy with them."

Whether the Accelerate member needs one-on-one mentorship, specialized education, or more, the program match makes each member's needs. EY is a network partner and — since everything is virtual — member companies have access to international experts through Impact Hub and its partners' networks.

"The ideal entrepreneur for the Accelerate membership is somebody who has already developed a solution — at least an MVP — for their social venture, whether it's a product or a service," Rodriguez says.

She cites Potentia as an example. The startup helps find jobs for adults with special needs, as well as educate corporations on how to work with and collaborate with these individuals. The company already has data and momentum, and the Accelerate program is helping the company to get to it's next stage.

"The idea is that we help people ladder up — no matter what stage you're at," Rodriguez says.

While growing the new program's membership — Rodriguez says it's her goal to get to 10 member companies my early next year — she's also focused on The Houston Innovation Summit and Impact Hub's Climathon.

The second annual Climathon, which begins Friday, November 13, has evolved since last year in a number of ways. First of all, it's completely virtual — which poses its own set of challenges and opportunities. Additionally, the event has several new partners — most of which didn't even exist in Houston last year, like Greentown Houston and Evolve Houston.

One of the biggest, most exciting changes for Rodriguez is the structure. While last year's event functioned as a hackathon, this year attendees can expect thought-provoking programming and collaboration.

"Last year, [Climathon] was directed at people who were more tech savvy," Rodriguez says. "What we found is people who are interested in climate action are a lot of times policy oriented or community activists and they don't know how they can plug into the tech space. It's more of an idea-a-thon. You don't have to develop a tech solution, but we can think about how we can activate more people for climate change."

Last year's Climathon took place during October. WIth it moving to November this year, it coincides with THIS, adding even more events to the week-long, impact-focused summit. THIS, which was designed to run alongside Global Entrepreneurship Week, also considers that week's themes, which are: education, ecosystems, inclusion, and policy.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions."

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.