The Salad Station and Chowbotics have teamed up to bring a salad-making vending machine to multiple locations across Houston. Courtesy of The Salad Station

A healthy foods concept has selected Houston as its next spot to bring its salad-making robot — aptly named Sally. The Salad Station, a Louisiana-based restaurant group, has partnered with California-based Chowbotics to bring salad-making vending machines to Houstonians.

Chowbotics invented Sally, which serves customizable, made-to-order salads, snacks, breakfast bowls, and grain bowls. Scott Henderson, founder and president of The Salad Station, tells InnovationMap that the discussion with Chowbotics about being the company's operational manager started in 2018.

"In seven states, from Texas to Florida, The Salad Station does operations for Sally the robot," says Henderson. "We both have a passion for bringing fresh products to people as many hours of the day as possible."

Henderson tells InnovationMap that he saw potential for the robot to increase opportunities for the chain's franchisees, increasing the amount of locations one person could own.

"We started looking at locations for Sally the robot and just in the Texas Medical Center alone, we feel like it could be 60 to 80 placements," says Henderson.

Due to the massive potential, The Salad Station entered into a partnership with Houston-based RoboFresh as the group's commissary to bring in more than 100 robots by 2022. Henderson tells InnovationMap that there will be 10 salad-making robots in the Texas Medical Center by 2020.

According to Henderson, the robot holds 22 unique ingredients, including two different lettuces, six topping options, and a dressing. The customer is able to customize their ingredients to create the salad of their choice. Payment is completed by credit card or Apple Pay, with most salads costing $7 to $8.

Henderson tells InnovationMap that the number one question they are asked at salad robot facilities is how the machine's ingredients stay fresh.

"We service the machines, at a minimum, twice a day, everyday," says Henderson. "Every morning and afternoon, we have people that go to the robots to bring fresh ingredients and to sanitize the outside of the machine."

Each ingredient is loaded in an airtight container, Henderson says.

"So, from the prepping in our Salad Station restaurants to delivering and installing it, there is no touch of product," says Henderson.

Henderson tells InnovationMap that each canister has an expiration date. For example, the expiration date on spinach is two days, so if the ingredient is not sold within that time frame, it no longer shows an option for the customer.

"Anytime the robot goes over 41 degrees for more than five minutes it disables itself, so customers cannot use the machine until we come back on site and change out the ingredients," says Henderson, adding that the robot maintains a consistent temperature of 34 degrees, keeping produce fresh and crisp.

The salad vending machines are just the beginning of growth in the Space City. The Salad Station is expanding into the Houston area with their first local brick and mortar location in Webster. In addition to the new opening, the franchise is expected to open additional locations across the greater Houston area in the next few years.

"That's where we're at for Texas, we're searching for local people, mainly in the Houston surrounding areas, that want to own their own business," says Henderson.

He adds that he believes the company's family-friendly values and hours will draw in more individuals to help open franchise locations of the fresh food chain.

The Salad Station was founded by Scott Henderson and his mother and business partner Cindy Henderson in 2012, the first store opening in Hammond, LA. Henderson tells InnovationMap that he started franchising the concept in 2014 and locating partners in nearby states to bring The Salad Station to new markets. The restaurant group currently has locations in Louisiana, Mississippi, Alabama, and Florida.

Johnmike Heroman, the head of franchise development at The Salad Station, tells InnovationMap that the chain is currently looking for potential franchise owners in the Houston area and feedback on placement options for Sally's next location.
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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”