An innovative, Houston-created tool instantly chills wine and spirits. Photo via thecoldcork.com

Great inventions reveal their value within due course, but there are those creations that tell their worth almost immediately, with a first look, image, or mere mention.

The Cold Cork, a malleable pouring device that instantly chills wine and spirits, falls into that category.

It seems like such a simple idea, but that’s the thing about inventions, isn’t it? Anyone can come up with an idea, but it’s the ones that can execute that idea that make it to the finish line and etch their names in the annals of creative glory.

“I had come home from the grocery store, right at the onset of COVID, and I wanted to have a glass of wine that I bought, but it was already room temperature, and I didn't want to put ice in it,” says wine-lover and former healthcare worker Michelle Kurkiewicz. “So, we started doing some research and came up with the idea for Cold Cork.”

Timing is everything, and because the nationwide pause caused by the COVID-19 pandemic offered Michelle, 33, and her husband Tyler, 30, plenty of free time, the dutiful duo was able to flesh out their labor of love.

Tyler and Michelle Kurkiewicz came up with the idea of the Cold Cork. Photo via thecoldcork.com

As it turns out, Tyler, a mechanical engineer by trade, had recently purchased a 3D printer back in January 2020, so he was able to use it to build hundreds of prototypes in-house to eventually arrive at a final design, which is based on the couple’s wedding champagne flutes.

So how does the Cold Cork work? Picture this: the wine-lover takes the Cold Cork out of the freezer (after a recommended 24 hours to thoroughly freeze), places it on top of the open bottle of wine and begins to pour.

As the liquid funnels through the stainless-steel coil, which is surrounded by a proprietary, food-grade cooling medium, the wine or spirits is chilled by 20 degrees in just 20 seconds.

To achieve the best results for red wine, pour the entire bottle through the Cold Cork into a decanter and enjoy.

And the best part? Not one part of the Cold Cork’s signature process alters the taste or composition of the drink in any way.

The device, priced at $64.95, chills liquids 20 degrees in 20 seconds. Photo via thecoldcork.com

“At first, we thought about whether the product should be inside the bottle or outside the bottle,” remembers Tyler. “But we quickly realized that there’s simply not enough room to do that amount of chilling inside a bottle. And we didn't want to have to pour any wine out. But we needed to make space to put some sort of chiller in the bottle. And so, we immediately started looking outside the bottle, and just with all the other wine gadgets, being bottle-topped and plugging in with a rubber stopper, that's immediately the direction we sort of drifted to.”

According to Tyler, the first couple of prototypes were made of a 3D filament. Initially, the idea was to focus on creating a cooling gel to compliment the coil, but that got a bit messy and, of course, there were too many wine taste-testing sessions to count.

“We definitely went through a lot of bottles of wine,” says Michelle. “But one of the first people that used our product was a sommelier and she loved it. We also gave one of our first production-level prototypes to a friend who is a manager at a restaurant. She used it on several occasions and said it was perfect for what she needed and seeing our product be used at a place that we frequented was extremely validating.”

Armed with the validation they needed to go to production, the wine-loving public could now have the product they needed to keep from having to throw all their wine in the refrigerator.

“The Cold Cork is really good for the people that maybe don't have those multi-zone fridges,” says Michelle. “We found a good niche with entry-level wine drinkers that don't have a wine fridge, but they want to drink their white wines still without being over-drank with ice cubes.

“That's really who we've been going after, and who we've seen has found a lot of value in the product. It's really the people that maybe aren't so prepared or maybe looking just for some more accessible solutions, whether it's because of the space in their apartment or financially, you know, it might be cheaper than a wine fridge. That's why we came up with the Cold Cork ourselves, because that was us, and so we kind of made a product that worked for us and found that there are a lot of people like that.”

The Cold Cork is available now and can be purchased directly from the company’s website for $64.95. In the future, more cork sizes and different colors will be offered, and more brick-and-mortar stores will carry the product. The couple pitched the idea and received investment from Trend Ventures at the 2022 Build Up Buttercup, an initiative that featured small business pitches for a select group of investors.

“We’ve gotten a lot of feedback directly from customers saying they use it a lot more than they thought,” says Michelle. “But then there are those people that are skeptical about how it works. That’s why I love to demo the Cold Cork in person.”

For a couple that met at a bar one night in downtown Houston, the Cold Cork is almost a poetic destination as a business endeavor and one that they both really relish.

“We both have our strengths, and we give each other a lot of support,” says Michelle.

“I’m very mechanically inclined, so I develop and invent, and Michelle is great with the marketing aspect and working with people to purchase the product,” adds Tyler. “In addition to the Cold Cork, we do have a couple of early projects that we are working on. I think there is a lot of opportunity with our technology to take what we have learned and fit that into different product lineups moving forward.”

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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.