This Texas train system is on track to keep operations green, thanks to a Houston-based company. Rendering courtesy of Texas Central

Texas Central, developers of the high-speed train proposed to run between Houston and Dallas, has selected a Houston-based company to oversee the environmental side of the project: Resource Environmental Solutions will help protect and enhance natural ecosystems and the environment throughout construction and operations.

RES will oversee plans to comply with US Army Corps of Engineers' requirements that the project restore, enhance, and preserve wetlands, streams, and environmentally sensitive habitats along the train's route between Houston and North Texas.

According to a release, RES is the largest ecosystem restoration provider in the United States. In the past decade, it has restored more than 58,000 acres of wetlands, enhanced more than 290 miles of streams, and planted more than 14 million restorative trees.

Recent projects include Maurepas Swamp in Louisiana, the Brooks Creek Wetland Mitigation Bank in Bowie County, and the Robinson Fork Stream Mitigation Bank, the largest floodplain restoration project in the northeastern United States.

RES is also working on the Bois d'Arc Lake Mitigation Area, a 16,600-acre reservoir being built in Fannin County to provide water services to 80 communities in North Texas that's the largest permittee-responsible mitigation project in U.S. history. The restoration area encompasses more than 8,500 acres of wetlands, 70 miles of streams, 3,200 acres of native grasslands, and 2,600 acres of non-wetland forests.

RES will help Texas Central meet regulatory requirements for environmental mitigation, collaborating with community leaders to identify local and regional conservation opportunities. The plan includes rebuilding and restoring wetlands and streams in the impacted watersheds, enhancing the viability of sub-watersheds that are close to the route.

Brian Trusty, VP of the Audubon Society, gives a thumbs up, stating that "Audubon believes the project is a win-win opportunity for both Texans and the wildlife in our state."

"Providing large-scale transportation opportunities that work to reduce carbon emissions, while supporting further economic prosperity and connectivity between the Dallas and Houston metro areas, is progressive and forward-looking," Trusty says. "Partnering with RES ensures the project will be done right, and we are thankful to see Texas Central take this step."

The project's scale will allow RES to identify not only isolated pockets along the route that require restoration, but also entire complexes of streams and wetlands suitable for improvement and conservation.

RES will select mitigation sites and designs that collectively improve the ecological functions of broad areas, including some near the Trinity River, Navasota River, Spring Creek, and Cypress Creek.

This environmental work, combined with innovations of an all-electric high-speed train system, will provide the most environmentally friendly travel choice between Houston and North Texas. The train is estimated to remove more than 14,630 cars per day from I-45.

Other ecological benefits:

  • As compared to highway development, for every one mile of high-speed railroad tracks, about 450 acres of farmland will be preserved.
  • The all-electric system will utilize the latest in green technologies, such as regenerative braking systems.
  • Texas will use the newest generation of Shinkansen trains, the N700 Supreme, which consumes seven percent less energy and weighs seven tons less than the previous model. Lighter trains result in less noise, vibration, and impacts on materials and land.
  • The route largely follows existing rights-of-way corridors, resulting in the fewest possible impacts to socioeconomic, natural, physical and cultural environments.

Consistent with Texas Central's commitment to create opportunities for small, minority, women, rural, and veteran-owned businesses, RES has engaged several small businesses to support its work for the project.

RES CEO Elliott Bouillion says in a release that it's possible to achieve both "environmental sustainability and advanced infrastructure."

"Texas high-speed train is an excellent example of how a modern, green infrastructure approach can be harnessed for both ecological and economic benefits," he says.

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This story originally ran on CultureMap.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.