Mayor Sylvester Turner and other local leaders joined the stage for the Ten Across summit in Houston this week. Photo by Natalie Harms/InnovationMap

Houston has an integral role to play in the energy transition, and that role was thoroughly discussed at a recent conference taking place in the Bayou City.

This week, Houston hosted the 10X Summit: The Future Is Here, an event by Ten Across — an organization that focuses on social, economic, and climate change issues across the region around Interstate 10 from Los Angeles to Jacksonville. The three-day conference featured guest speakers who spoke to resiliency, water, the future of energy, and more.

Among these speakers included a handful of Houston researchers, political figures, and innovators — and much of their conversations overlapped related topics and themes, from Hurricane Harvey's legacy and impact on the business community to the role the city will play in the energy transition.

When it comes to the energy transition, here are the key messages Houston leaders shared with 10X attendees.

The energy transition can't happen without Houston

The topic of the energy transition came up right out of the gate for the summit. At the welcome reception on Tuesday, Bobby Tudor, CEO of Artemis Energy Partners and founder and former CEO of Tudor, Pickering, Holt & Co., spoke to the evolution of the industry and how Houston is a major factor in the energy transition's success.

“I don’t think (the energy transition) is going to happen without (Houston)," Tudor says at the fireside chat with Wellington Reiter, executive director of Ten Across. "There's a notion that the transition is inevitable. It’s inevitable — only if our technology continues to advance and improve, only if new assets get deployed, only if capital supports it, and only if the people who know and understand the energy systems are leaning in to make it happen.”

For Tudor, who served as chair of the Greater Houston Partnership in 2020 and made it his mission to communicate the importance of industry evolution during his tenure, Houston businesses motivated by opportunities in business should be looking at the energy transition.

“We’re very good in Houston that, when we see a dollar bill lying on the ground, we bend over and pick it up. Right now, there’s fantastic opportunity in the energy transition space," he says. "We have both a responsibility and an opportunity to be the leaders in the global energy transition.”

Mayor Sylvester Turner in his chat with Reiter on Thursday addressed how some might think that Houston — a headquarters for some of the biggest oil and gas giants — might not be the right city to lead a cleaner energy system, but Turner argued that's exactly why it has to happen here.

“We are the energy capital of the world," he says. "The reality is we have some of the largest greenhouse gas emitters principally located right here in Houston. To the extent of leading an energy transition, the impact is not just locally. The impact is globally.”

Barbara Burger, former president of Chevron Technology Ventures and an energy tech startup adviser, explained how integral the relationship between the energy industry and Houston is.

“As the energy system evolves, so does Houston," she says. “I think it’s our opportunity to lose."

The role of corporate incumbents 

Burger's discussion, which took place on Wednesday, spoke to the role of incumbents — corporations that have been operating in the energy industry for decades — in the transition. She explained how the process can't move forward without these parties.

“The incumbents need to be a part of the energy transition. There are parts of our society that don’t want them to be, and I find that unfortunate," she says. "For one, we’re not going to decarbonize the energy system unless they are a part of it. Two, there are a lot of skills and capabilities and assets in the incumbents to do that.

"What I don’t think the incumbents will do is they won’t lead it," she continues. "Many will be leaders in the new energy system, but they won’t be the ones first up the hill.”

Burger compares the energy and the automotive industries. Tesla acted as a disruptor to major auto companies, and then they followed suit. The disruptors and catalysts the energy industry will be a combination of startups, investors, governments, universities, and employee bases.

“We’re not going to throw away the current energy system," she says. "We’re going to evolve it and repurpose it.”

Houston has the ingredients

Tudor addressed the existing infrastructure — from physical pipes to expertise and workforce — that Houston has, which makes for an ideal location for innovation and progress in the transition.

“For a lot of reasons, it’s very clear that unless Houston leans in, we’re not going to find the solutions we need to transition our energy systems to much lower CO2 emissions," he says.

The GHP established the Houston Energy Transition Initiative in 2021 to concentrate Houston efforts within the future of energy. Tudor says this initiative is focused on what can be done now in town — attracting clean energy startups, developing a hydrogen hub, building facilities for green hydrogen production — to lead to a better future.

“We want to look up 20 years from now and find Houston is still — if not more than ever — the energy capital of the world," he says. "We believe that energy systems globally in 20 years will look quite different from how they look today. And that means Houston will look very different from how it looks today."

Burger emphasized some of the challenges — as well as opportunities — the city has considering its long history within the sector.

“Houston has benefitted from a vibrant, strong U.S. energy industry,” she says. “Keeping strong companies and keeping Houston attractive for the energy business is critical.”

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.