Houston named a best place to work in tech, Capital Factory opens $100,000 contest, and more innovation news

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Texas cities dominate list of best places to work in tech, a startup contest is accepting applications, Amazon invests in Houston community, and more local innovation news. Getty Images

Just like Houston's temperatures, the Bayou City's innovation news is heating up for the summer. From a new startup competition and a big donation from Amazon to Texas cities dominating a list of best places to work in technology, here's a roundup of innovation news happening in town.

Study finds greater Houston area ranks as best place to work in tech

Four Texas metros appear on the ranking. Chart via SmartAsset

A new study from SmartAsset identified the best places to work in technology, and Houston ranked at No. 15. The researchers looked into the country's top 50 populated areas across five metrics: percentage of workers employed in tech, average salary for tech workers, ratio of average tech salary to average salary across all fields, percentage of currently listed bachelor's jobs that are in tech and cost of living.

Texas was well represented on the list, and three Lone Star State metroplexes landed on the list ahead of Houston. Dallas-Fort Worth-Arlington tied for the No. 3 position with Raleigh, North Carolina. Meanwhile, central Texas' Austin-Round Rock and San Antonio-New Braunfels tied for No. 7.

The study found that most of these top cities reside in the south, and the northeastern part of the country ranked poorly on these metrics.

Capital Factory launches $100,000 startup competition

Calling all cognitive tech startups. Photo via austinstartups.com

Austin-based Capital Factory, which has a presence across the state, has opened applications for a $100,000 contest for tech startups. The Human Performance Investment Challenge is looking for hardware and/or software solutions that enhance physical or cognitive capabilities, according to an article the organization posted.

The challenge will conclude at Fed Supernova, a virtual event on July 15. The event is in collaboration with the Army Futures Command's Innovation Combine and xTechSearch programs. Applications are open now and close June 28.

Amazon teams up with Houston Food Bank to feed at-risk seniors

The Houston Food Bank is working with Amazon to feed senior citizens. Photo courtesy of Houston Food Bank

Last month, Amazon made a strategic donation focused on providing food to senior citizens disproportionately impacted by COVID-19. The tech giant's Amazon Flex sent drivers around town to make contactless deliveries to residents' doors, and, in just two days after launching, Amazon has delivered over 3,000 pounds of food — representing more than 2,000 meals.

"For so many of our senior citizens, the pandemic is especially troubling as they have health concerns, limited mobility and need assistance for such regular tasks as grocery shopping," says Brian Greene, president and CEO of Houston Food Bank, in a news release. "Because this population needs help, we wanted to add direct food deliveries for them, and we are so thankful to Amazon for stepping up to make this happen for our beloved senior citizens."

Amazon's efforts within the Bayou City are just one part of its commitment to deliver millions of meals across the country. In addition to the donated delivery service, Amazon has gifted a $50,000 COVID-19 response grant to the local organization to go to operational needs and food supplies.

"Communities around the world are facing the COVID-19 pandemic together, and in Houston we're proud to be doing our part to support our local community," says Bri Tye, general manager at Amazon's Fulfillment Centre in Katy, in the release. "The donation of $50,000 to the Houston Food Bank, and Amazon's Flex deliveries will go directly to helping feed seniors and families who need it most."

Houston fintech startup launches new product

HighRadius has premiered a new software product. Photo via highradius.com

Houston-based fintech startup, HighRadius, which provides software solutions and automation technology, announced its new RadiusOne A/R Suite for mid-sized businesses.

"We launched the RadiusOne B2B Network to facilitate suppliers and A/R teams to digitally connect with their buyers and A/P teams for faster processing of receivables and payments. Currently, the network has millions of active businesses," says Sashi Narahari, founder and CEO of HighRadius, in a news release. "The RadiusOne A/R Suite will provide the essential apps for A/R teams at mid-sized businesses to instantly plug their ERPs and A/R processes into this network and digitally connect with their buyers across the globe."

The new product is especially key in today's work-from-home environment in order to prevent slowdowns in accounts receivable departments.

"COVID-19 is putting a lot of working capital strain on businesses globally," Narahari says. "We are hoping to help by automating clerical A/R processes for mid-sized businesses and by reducing the friction for supplier A/R teams to digitally collaborate with their buyers and A/P teams."

The Cannon partners with minority-focused angel investment group

The Business Angel Minority Association launched at a breakfast event in March. Photo by Nijalon Dunn

The Cannon — an entrepreneurial hub — has joined forces with The Business Angel Minority Association, or baMa, to prioritize diversity within angel investing in Houston.

"Diversity plays an important role in early-stage investment decisions. The existing Business Angel associations are not diverse enough and this translates to a lack of pre-seed and seed angel investment in Minority-led startups", says Maria Maso, founder and CEO of baMa, in a news release.

The organization launched earlier this year to connect angel investors to minority-led startups. This partnership is in line with The Cannon's commitment to diversity, says the Cannon's CEO, Jon Lambert.

"baMa's mission to fill the glaring need for an early-stage investment focus on minority-led startups and/or startups targeting minority-driven markets is fundamental to The Cannon's vision to deliver every entrepreneur access to the startup resources needed to thrive," Lamber says in the release.

"For us, community is diversity – our partnership with baMa will extend and enhance the support system we are passionately growing and will provide baMa with access to our expanding community of startups and partners. We're excited to see where this partnership takes us – there is so much alignment in our desire to help the entire entrepreneurial community, we are expecting to accomplish big things together."

UH program addresses need for technology teachers

UH's teachHOUSTON program is preparing the next generation of technology educators. Photo courtesy of Chris Watts/uh.edu

With the number of jobs within technology expected to grow, the University of Houston has geared up to train the future's tech educators. UH's teachHOUSTON program, which trains STEM teachers who work in economically disadvantaged high schools within Houston, recently received $1.2 million from the National Science Foundation to continue its mission.

The funding will go toward a new program called UH-ACCESS — short for Advancing Cultural and Computational Engagement in STEM Scholars. The program, which begins this fall, will train 30 UH students from varying disciplines to teach computer science, physics and technology at the high school level.

"Our goal is to prepare a diverse group of teachers who will inspire students to become the country's next technologically advanced, highly-skilled workforce," says Paige Evans, associate director of teachHOUSTON and principal investigator on the project, in a news release.

The selected UH-ACCESS scholars will receive a $12,000 scholarship per year for two years, and they will work in the field across Houston, Alvin, Pasadena, Spring Branch, and Cy-Fair Independent School Districts.

"We are trying to find potential teachers who already exhibit a sociocultural awareness," continues Evans. "Research has shown that students do better in science, technology, engineering and math if the content is connected to their community and culture."

HCC launches tech tool for job hunters

HCC is helping job hunters across the city. VioletaStoimenova/Getty Images

Houston Community College has launched a new tool for job hunters that identifies occupations and the accelerated certificate programs within the higher educational system. JobsNowHouston.org will help Houston's unemployed gain key skills and certifications to make them a more marketable employee.

"COVID-19 has challenged us all, forcing us to rethink every facet of education and community responsiveness," says Dr. Cesar Maldonado, chancellor of Houston Community College, in a news release. "JobsNowHouston.org will connect people with the resources they need to gain the skills and knowledge necessary to compete in our new workforce and is a great example of how everyone at Houston Community College is working even harder to provide training and education to fill in- demand jobs."

According to the release, COVID-19 pushed over 1.5 million Texas residents into unemployment but — at the same time — nearly 481,000 job openings have been posted recently. HCC hopes its JobsNowHouston.org initiative can connect the dots to more easily facilitate retainings and upskilling for these unemployed.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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