University of Houston wraps up first cohort of program to turn innovators into entrepreneurs

fresh founders

Six members of the UH community participated in the inaugural Innov8 Hub's Innovators to Founders Cohort. Photo via UH.edu

A new accelerator at the University of Houston recently wrapped its first program for a cohort of five early-stage startups.

Known as the Innov8 Hub's Innovators to Founders Cohort, the accelerator is a founder-driven program in partnership with the UH Technology Bridge, the Innovation Center, and the Texas Gulf Coast Small Business Development Center (SBDC). Innov8 is designed to aid six to eight aspiring entrepreneurs bring their concepts to market and assist them in applying for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants.

Founders recently showcased their work before potential partners and investors at the hub's first-ever Startup Pitch Day following the conclusion of the 12-week program.

“The goal of the programs is for the founders to launch new ventures and develop business plans they can use to raise money and attract C-suite level employees to join their team,” Tanu Chatterji, associate director of startup development at Tech Bridge and co-founder of Innov8 Hub, said in a statement. “These programs aren’t classroom-teacher driven so the founders have to commit to engage and spend the time necessary to reap the benefits.”

The Innovators to Founders Cohort runs for three months each semester. Cohort members will devote three hours each week to the program. Photo via UH.edu

The inaugural cohort included:

Shoujun Xu, UForce Biotechnology: Xu is a chemistry professor at UH and has developed a new technique of super-resolution force spectroscopy, or SURFS, and plans to launch his company, UForce Biotechnology, in the future. He aims to use the SURFS technique to advance drug screening. His pitch at the Startup Pitch Day was named the best of the night, and Xu went home with $7,500 in legal services and one year of coworking space free of charge.

Easy Anyama, ODX Health: Anyama is a fourth-year student in the UH College of Optometry. His company, ODX Health, aims to improve "data harmonization, interoperability and integration in eyecare to reduce inefficiencies and enhance health outcomes," according to UH.

Jeremy Tee and Easy Anyama, Ringit: Anyama joined fellow fourth-year student in the UH College of Optometry Jeremy Tee in a second pitch, Ringit. The startup aims to provide a low-cost medication management solution for the visually impaired. It is developing an adaptive labeling system that helps the visually impaired identify their medication and dosages independently via intuitive, "touch-based features," according to UH.

Jan Beetge, AltiSora: Beetge has developed "Botox for wood." The product is made from high- sustainability raw materials that are non-hazardous and non-toxic. Potential applications include waterproofing of electronic equipment or electrical cables or connections in cables, such as cables used in marine applications, according to the company's website.

Jason Shi, Smart Planter Project: Shi is developing a "high-tech planter, a device that autonomously takes care of your plants and keeps them healthy while you’re gone," according to UH. He aims to soon test the product with customers.

The Innovators to Founders Cohort runs for three months each semester. Cohort members will devote three hours each week to the program.

The Innov8 Hub also offers an SBIR/STTR Support Cohort and a WKI Program for Student Entrepreneurial Support Cohort.

Last year, UH also named eight graduate students to its first-ever UH-Chevron Energy Graduate Fellows cohort.
A new program launched by two UH-based organizations will help early-stage startups commercialize, apply for grants, and more. Photo via UH.edu

University of Houston launches new collaborative program for startups in Houston, Gulf Coast Region

ready to grow

Two University of Houston organizations have partnered up to further support early-stage startups in the Gulf Coast Region.

The university announced this month that its UH Technology Bridge and the UH Texas Gulf Coast Small Business Development Center are now accepting applications for a new, collaborative program that will help innovators and entrepreneurs develop a pitch or commercialization plan. The program will also guide participants in applying for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants and other investments.

Applications are open to those with the university and across the region.

"We are excited to partner with the University of Houston Technology Bridge to provide this valuable support to early-tech startups in the Texas Gulf Coast region," Steven Lawrence, director of the UH Texas Gulf Coast SBDC Network, says in a statement. "Our program is designed to help innovators take their ideas to the next level and prepare for success in the marketplace."

"Our goal is to help innovators turn their ideas into successful businesses, and this partnership will help us achieve that goal," Tanu Chatterji, Associate Director of Startup Development at UH, echoes in the news release.

The UH Texas Gulf Coast SBDC Network is one of 14 SBDCs in the Texas Gulf Coast Region that's part of UH's C.T. Bauer College of Business and funded in part by the U.S. Small Business Administration. The centers provide no-cost and affordable business training and advising.

The UH Tech Bridge focuses on providing research and development space to UH-affiliated startups and entrepreneurs. The 15-building complex and its 31,000 square feet of incubator space houses more than 20 small companies and startups that provide internship and learning opportunities for UH students, along with several federally funded research centers and institutes.

Earlier this year, the Tech Bridge received a $2.875 million grant from the U.S. Department of Housing and Urban Development. The grant is slated to benefit the UH Industry & International Innovation Hub and will establish The Deck Innovation & Coworking Center.

Ramanan Krishnamoorti, the vice president of energy and innovation at the University of Houston who oversees the UH Technology Bridge, spoke with the Houston Innovators Podcast earlier this summer about UH's plans to build a central campus hub for innovation and the need to encourage more innovation and entrepreneurship.
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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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