Houstonians are struggling the most with work-related stress, WalletHub found. Photo via Getty Images

Stress is an unavoidable part of life, but a new report by WalletHub shows Houston residents are far more stressed out than any other city in Texas.

Houston ranked No. 18 out of 182 of the largest U.S. cities based on work, financial, family-related, and health and safety stress, according to WalletHub's "Most & Least Stressed Cities in America (2024)" report. 39 relevant metrics were considered in the report, including each city's job security, the share of households behind on bills within the last 12 months, divorce rates, crime rates, among others.

Houston was ranked the most stressed out city in Texas, but it's still far less stressed than many other U.S. cities. Cleveland, Ohio took first place as the most stressed city in America, followed by Detroit, Michigan (No. 2), Baltimore, Maryland (No. 3), Memphis, Tennessee (No. 4), and Gulfport, Mississippi (No. 5).

Out of the four main categories, Houstonians are struggling the most with work-related stress, ranking No. 13 nationally. The report found Houston has the No. 1 highest traffic congestion rate out of all cities in the report. But at least Houston drivers are solidly average, as maintained by a separate Forbes study comparing the worst drivers in America.

Houston workers can rejoice that they live in a city with a generally high level of guaranteed employment, as the city ranked No. 151 in the job security comparison. The city ranked No. 16 nationwide in the metric for the highest average weekly hours worked.

Houston fared best in the financial stress category, coming in at No. 72 nationally, showing that Houstonians aren't as worried about pinching pennies when it comes to maintaining a good quality of life. The city ranked No. 39 in the comparison of highest poverty rates.

Here's how WalletHub quantified Houston's stress levels:

  • No. 17 – Health and safety stress rank (overall)
  • No. 36 – Family stress rank (overall)
  • No. 63 – Unemployment rates
  • No. 81 – Percentage of adults in fair/poor health
  • No. 95 – Divorce rate
  • No. 96 – Percentage of adults with inadequate sleep

WalletHub analyst Cassandra Happe said in the report that living in particularly arduous cities can play a big role in how stressed a person is, especially when considering uncontrollable circumstances like family problems or work-related issues.

"Cities with high crime rates, weak economies, less effective public health and congested transportation systems naturally lead to elevated stress levels for residents," Happe said.

Happe advised that residents considering a move to a place like Houston should consider how the city's quality of life will impact their mental health, not just their financial wellbeing.

Other Texas cities that ranked among the top 100 most stressed cities in the U.S. are:

  • No. 20 – San Antonio
  • No. 38 – Laredo
  • No. 41 – Dallas
  • No. 47 – Corpus Christi
  • No. 61 – El Paso
  • No. 68 – Fort Worth
  • No. 71 – Brownsville
  • No. 75 – Arlington
  • No. 78 – Grand Prairie
  • No. 88 – Garland
The full report and its methodology can be found on wallethub.com

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This article originally ran on CultureMap.

Life is much more difficult when you're stressed out. Photo via Getty Images

Troubled Texans are the 10th most stressed out people in America, report finds

new report

There is a plethora of reasons to be stressed out in 2024. Among the list of grievances are budgeting woes, lapses in addressing racial inequity, a significant amount of drunk driving, and prohibitively high healthcare costs.

So it comes as no surprise that Texas was ranked the No. 10 most stressed state of 2024, according to the latest annual report from WalletHub. Texans' stress levels are only slightly better than they were in 2023, when the Lone Star State ranked No. 9.

The personal finance website compared all 50 states across 40 unique metrics to determine every state’s worries on certain issues, such as employment, finance, health, or family-related stress.

Here's how Texas performed in the major categories in the study:

  • No. 5 – Work-related stress
  • No. 8 – Family-related stress
  • No. 11 – Health- and safety-related stress
  • No. 23 – Money-related stress

Texas employees have the second-longest workweek in the nation, the report found, placing the state right behind Alaska and tied with Wyoming. Places like Houston, Corpus Christi, and San Antonio are a few of the most stressful U.S. cities for workers in 2024 (with several other Texas cities not far behind), clearly showing that there's much more work to be done to alleviate Texans' work-related stress.

Hardships with work may have an influence on Texans' ability to rest at night, as the report additionally found Texas fell behind into No. 23 for its share of adults that get adequate sleep.

Other Texas-sized stress factors like crime rates, housing affordability, health troubles, and poverty rates also put a damper on residents' well-beings. Texans have the fourth lowest credit scores in the nation, the ninth highest share of adults with fair or poor health, and the 11th highest number of residents living in poverty.

It's not just young and middle-aged adults who experience these worries, the report claimed.

"[E]very age group except people 65 and older reported being under more stress in 2023 than they were in 2019 before the pandemic," the report's author wrote.

WalletHub analyst Cassandra Happe suggested a few ways frazzled Texans can try to improve their stress levels, such as exercising, participating in hobbies, going on vacations — of course, in whatever capacity that is most accessible — and seeking help from a mental health professional.

"What many people don’t realize, though, is that changing location can also be a big stress reducer," Happe added. "For example, states that have lower crime rates, better health care, and better economies tend to have much less stressed residents."

Texans surely aren't envious of Louisiana, which traded places with Mississippi (No. 2) in 2024 to become the nation's No. 1 most stressed out state. Louisiana residents experience the third highest work- and health-and-safety-related stress, the fourth highest money-related stress, and the 10th highest family-related stress. Louisianans may want to try some breathing exercises in their spare time.

Texas residents can, however, be filled with jealousy over Minnesota (No. 50), which was crowned the least stressed out city in America. Maybe that's where Texans need to be taking vacations.

The overall top 10 most stressed states are:

  • No. 1 – Louisiana
  • No. 2 – Mississippi
  • No. 3 – Nevada
  • No. 4 – New Mexico
  • No. 5 – Arkansas
  • No. 6 – West Virginia
  • No. 7 – Alabama
  • No. 8 – Kentucky
  • No. 9 – Oklahoma
  • No. 10 – Texas
The full report and its methodology can be found on wallethub.com.

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This article originally ran on CultureMap.

Work life in H-Town is hard. Photo by Elisa Ventur on Unsplash

Houston named No. 1 most stressful city for workers in U.S. in new report

by the numbers

Feeling totally stressed about work? Fellow Houstonians feel the pain.

In a new report from LLC.org, Houston was designated the most stressful city to work in. In fact, not one — but five — Texas cities made the top 10 most stressful cities for workers. Ouch.

LLC.org’s analysis looked at eight different categories such as average commute time, average weekly hours worked, income growth rate, and more. Each of the 170-plus cities researched in the report have a population of at least 150,000 people – which adds up to a lot of stressed out folks nationwide.

Houston earned its most stressful city ranking due to its nearly 53-minute average round trip daily commute, not to mention that one in three people in the city are on the road before 7 am every morning. To top it off, Houston’s percentage of workers without health insurance is 30.4 percent, which is significantly higher than the national average of 10.5 percent. (That’s a lot to be stressed about.)

Just after Houston is Arlington (No. 2) and Dallas (No. 3). While Arlington earns its second most stressful city rank for its 39.9 hour average daily work week, Dallas ranked ninth for the longest work week out of all cities in the analysis. The average Dallas laborer works 40.2 hours a week, which is greater than the 38.7 hour national average. At least Dallas’ average commute is a little lower than Houston and Arlington – at 51.4 minutes round trip.

Rounding out the top five are Memphis, Tennessee (No. 4) and Las Vegas, Nevada (No. 5) with Corpus Christi taking the No. 6 spot. Other Texas cities that made the list include Fort Worth (No. 8), San Antonio (No. 12), Garland (No. 13), Brownsville (No. 15), El Paso (No. 22) and Irving (No. 26).

The top 10 most stressful cities for workers are:

  • No. 1: Houston
  • No. 2: Arlington, Texas
  • No. 3: Dallas
  • No 4: Memphis, Tennessee
  • No. 5: Las Vegas
  • No. 6: Corpus Christi, Texas
  • No. 7: Fayetteville, North Carolina
  • No. 8: Fort Worth, Texas
  • No. 9: Moreno Valley, California
  • No. 10: Modesto, California
In an examination of the least stressful cities for workers, not a single Texas city made the top 10. Madison, Wisconsin earned the ranking of least stressful city to work in. It must be nice to have a 36.6-hour average workweek and short average round trip commute of 37.4 minutes. If only.The full report can be found at llc.org.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.