AI's true potential lies in its ability to enhance human capabilities, not replace them. Photo via Getty Images

The rapid advancement of artificial intelligence is forcing businesses to evaluate how they will manage the inevitable changes this technology will bring. With its ability to automate tasks, analyze large amounts of data, and provide detailed insights, AI offers an enormous opportunity for businesses of all sizes. However, realizing this potential requires a strategic approach that positions AI as a powerful partner, rather than a replacement for human ingenuity.

The British Council reports that an estimated 65 percent of today's students will eventually work in professions that have yet to be conceived. With the emergence of new AI, this projection emphasizes the importance of cultivating a versatile skill set that allows us to adapt to the ever-changing landscape. It also underscores the importance of having a strategy that embraces the division of labor between humans and machines.

What this means is that an AI strategy shouldn't just be about automation – it should also incorporate an understanding of the human-AI partnership that will be necessary for future success. By using the concepts of automation, augmentation, and autonomy, businesses can unlock the full potential of AI to boost efficiency, enhance decision-making, and ultimately drive continued success.

Automation: Delegating to the AI

We know AI can automate many tasks in a business. However, we should also look at automation from a strategy standpoint by asking, "What tasks can be fully delegated to the AI?" Answering this question might include considering routine, repetitive, and time-consuming tasks that shouldn't require human intervention or those that would be more susceptible to human error. The goal here should be to identify tasks that don't benefit from human nuance, meaning asking questions about time, precision, and compliance could offer even more value.

  • Time. What tasks are time-consuming and could be completed quickly with well-written instructions?
  • Precision. What tasks require precision that is difficult for humans to achieve?
  • Compliance. What tasks involve critical safety procedures or adherence to strict compliance that humans might overlook?

Augmentation: Using AI to boost your potential

Beyond automation, AI's true power lies in its ability to boost human capabilities. In this lens, you should ask, "How can the AI boost my output potential?" Think of AI as a skilled assistant that can analyze vast datasets, identify complex patterns, and present insights that aren't readily apparent to humans alone. The focus here is on tasks that still require a human touch but can benefit from computers' speed and data processing power. When exploring this further, consider asking questions about skill boosts, assistance, and focus.

  • Skill boosts. What tasks am I doing that I understand but need to be an expert at?
  • Assistance. What tasks still require a human's touch but could use processing or speed boosts?
  • Focus. What tasks are causing employees to spend more time on tools and less on goals?

Autonomy: The importance of humans in the loop

One question that comes up frequently when discussing AI is whether it will replace a particular set of jobs. My thoughts, however, are that while AI is remarkably powerful, the key to making all this work is understanding that not every task requires automation. In fact, some tasks would suffer from automation. This step requires you to ask, "Where are human emotion, creativity, intuition, and oversight essential?" Autonomy, in this sense, means digging into creativity, intuition, and uniqueness.

  • Creativity. Does this task require a level of creativity that a machine can't replicate?
  • Intuition. Does this task require emotional awareness that a machine can't discern?
  • Brand Uniqueness. Does this task represent a part of my brand that shouldn't be automated or machine-driven?

AI brings a lot to look forward to. It’s fair to say it’s on its way to transforming the world, but it's important to remember that the businesses that strategically embrace a human-centered approach to integrating AI into everyday business activities are the ones that will thrive. The three A’s: automation, augmentation, and autonomy, provide an essential foundation to begin this journey. By understanding the best applications for each aspect of AI, businesses of all sizes can discover areas for increased efficiency, more thoughtful decision-making, and a competitive edge that drives long-term success. AI's true potential lies in its ability to enhance human capabilities, not replace them.

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Kelsey Ruger is the chief technology and product officer for Hello Alice.

The concept is simple: Think before you act in marketing. Getty images

How to think before you act when it comes to marketing for your company

Strategizing for startups

If there were a joke about how entrepreneurs treat their marketing — and there totally isn't — it would go something like this.

An entrepreneur walks into a bar. Before the bartender can ask, the entrepreneur says, "I want a drink and I need it ASAP."

"What type of drink?", the bartender asks, motioning to the hundreds of bottles behind him.

"I need a drink that is refreshing, doesn't make me too drunk and makes me feel like I'm getting my money's worth."

The bartender begins listing drink after drink, and the entrepreneur, sometimes sampling the drink, turns each one down.

At long last, the entrepreneur climbs behind the bar, grabs a glass, pours in some ice and soda water, and takes a long sip.

"This is exactly what I wanted," the entrepreneur proclaims, "Why didn't you offer me this in the first place?"

The moral of the story? When it comes to marketing, entrepreneurs tend to know exactly what they want, yet they focus on quenching that immediate thirst, not knowing why they're in a bar in the first place.

The idea of your first step is nothing compared to the reality of your second. You can know something but applying those principles to starting and/or running your own business can be difficult.

When we (yes, I'm an entrepreneur too) look at marketing, we often confuse tactics with strategy. I see a problem and immediately need a tool to fix it. Hanging a picture? Where's the hammer?!

While it's tempting to lead with the tactics (i.e. website, brochure, display ad, video, etc.), they can be misguided. This can drain precious resources. Strategy can inject purpose into everyone's mindset.

Marketing efforts must be considered a sequence of events that, when lined up in the right order, produce results that are repeatable, more effective, and can lead to a predictable type of profitability.

Where careers rise and fall is the accuracy of any particular strategy. Since we're talking about accuracy, let's use an archery metaphor. Sure, you can consistently hit a target from five feet away. The farther away you get, though, the more you have to consider crosswind, the arrow's trajectory, and your own focus in order to hit that bullseye. And that's all part of a process of whittling down the variables you don't know or can't control.

It's the same with marketing. The more time you've spent preparing, studying, testing, and strategizing, the more often you will accurately target that bullseye.

Where a lot of entrepreneurs also miss the mark is not clearly understanding the core business issue. If you're lost in the forest (and it can totally feel like that sometimes), you're supposed to be quiet when hunting for food but you supposed to make a lot of noise when trying to get rescued. That's what mixing up a core business issue can do. As a process where you're whittling down the variables, marketing is a sequence, like this:

Graphic from Jarred King

Seems simple enough, right? But the process itself is dependent on the intangible pieces in between the steps. This is what happens between the "knowing" and the "doing." So, the above graph should really flow like this:

Graphic from Jarred King

Usually, the typical entrepreneur prefers to start with step four and just "get sh*t done." The problem with this approach is that it can either be the wrong solution (you're hunting with a rock instead of an arrow) or the wrong effort (you're staying quiet when you should be hollering).

The difficulty here is that the desired effect doesn't happen overnight. It rarely solves "today's problems" today. Even worse, it might require a larger investment. Without fundamentally understanding your business problem, any solution offered will be less effective, more expensive, and more wasteful of time and resources.

Instead, simply start with the business problem and then follow the above sequence to leverage "the doing" part in order to develop "the knowing" part. This doesn't have to be a drawn-out process, and there are a ton of free resources available online to help conduct your own research, analysis, and planning.

Ultimately, I'm saying "think before you act." It's not difficult to understand. The challenge for entrepreneurs is that they are faced with hundreds of important and, often, business-critical decisions each day. We can't help but to react, then decide, and move on. While our gut and grit got us to this point of success, it's strategy that will take us from surviving to thriving.

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Jarred King is the founder and president of Swagger Agency, a full-service marketing firm as well as the current president of Entrepreneurs' Organization - Houston. King also serves on the board of InnovationMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."