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Expert: Houston's at a critical inflection point amid energy transition

guest column

In 1914, Winston Churchill faced a difficult decision. Over two decades before his first term as Prime Minister during World War 2, he oversaw the entire Royal Navy as First Lord of the Admiralty. Shipbuilding technology was rapidly evolving in that era and one of the key questions was whether to use coal or oil as fuel for the large ships in the fleet. Coal was the more proven technology at that point and the British had a strong supply chain across the Empire. Oil was lighter and easier to operate, but the worldwide supply and infrastructure were still limited.

Ultimately Churchill was persuaded by Admiral Jacky Fisher and others to convert the entire fleet to oil. To resolve the supply chain issue, the British government bought a majority stake in Anglo-Persian Oil Company, which became BP. The Royal Navy was possibly the largest consumer of fuel worldwide at the time, so this decision had a major effect on the energy transition in that era. Within 30 years, steam engines were no longer used for transportation in most of the world.

In that same decade, Houston emerged as a leading energy hub in the United States: Humble Oil was founded, the Houston Ship Channel was dredged, and the Baytown Refinery was constructed. World War I in Europe, and the mass adoption of cars in the US spurred a major increase in demand for oil. Oil went on to dominate the global energy market, providing cheap and reliable transportation, industrial production, and materials. Houston grew and prospered along with it to become the 5th largest metro area in the country today.

Over a century later, the global energy industry may be at a similar inflection point. According to IEA, the electric vehicle market more than tripled from 4 percent in 2020 to 9 percent in 2021 to 14 percent in 2022. Major automakers like GM, Ford, Volkswagen, Mercedes, and Volvo have pledged to become all-electric by early-to-mid 2030s. Similar commitments are being made in commercial trucking and shipping.

At the same time, the electric power grids in the United States and many other nations are undergoing a rapid shift to renewable energy. Lazard’s annual Levelized Cost of Energy (LCOE) report showed that by 2015, wind and utility-scale solar power in the US were cheaper than all other technologies on a $/MWh basis; the gap has only grown wider since. EIA data on new power generation capacity in the US for 2020-2023 shows that solar, wind, and energy storage combined have ranged from 74 percent to 81 percent while natural gas has ranged from 14 percent to 22 percent and other fuels less than 5 percent.

All of these figures show market trends that are already happening, not projections of what may happen if the technologies improve. This leads to a natural question: will the growth of EVs and renewable energy reach a limit and tail off? Or will this trend continue until the internal combustion engine and fossil fuel power are replaced like steam engines were before? Both EVs and renewable energy are experiencing insatiable market demand in developed markets but have hit other barriers such as supply chain and infrastructure. However, just as the oil industry itself demonstrated in the past, those constraints can be overcome if the push is strong enough.

The year 2035, only 12 years away, is a major deadline for the transition. The US government and the EU have both set it as a target to complete the transition to EVs. In the US electric power industry, BloombergNEF projects that 126 GW of US coal power will retire before then. S&P also forecasts 85 GW of new energy storage will be online, which will help resolve intermittency and transmission issues that have limited the role of renewable energy up to now. That paints a picture of a radically different energy industry from the one we see today; one with oil demand at a fraction of its current levels and natural gas demand in rapid decline as well.

These market trends have drawn a variety of responses in Houston and other energy hubs, ranging from enthusiastic adoption to cautious skepticism to firm denial. Two recent examples of this range are BP CEO Bernard Looney advocating for continued investment in renewable energy and Shell CEO Wael Sawan emphasizing a move away from them due to lower returns. Business leaders should always be aware of threats to their long-term operations, regardless of their personal opinions on an issue. While demand for oil generally remains strong, every business in the energy industry should be prepared for the scenario that all new cars sold in a decade are electric. There is a graveyard of companies like Kodak, Sears, and Blockbuster Video that failed to act on an existential market threat until it was too late.

Plans for the transition can look different from company to company, but Houston is full of resources that can help with planning and deployment. The workforce, financial sector, and professional services can adapt to new energy technologies from their existing oil and gas expertise. Industry organizations like the Houston Energy Transition Initiative, Renewable Energy Alliance Houston, and the energy policy centers at Rice University and the University of Houston can help leaders make connections and discuss new technologies.

The burden is on every business leader to make use of the time remaining, not only to make plans for the changes coming in the energy industry, but to implement those plans. The question the Houston business community must be able to answer today is “Are we going to be ready for 2035?”

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Drew Philpot is president of Blended Power, a renewable energy consulting practice based in Houston. This article originally ran on EnergyCapital.

Cancer-fighting startup partners with Houston cell therapy accelerator

marching on

When it came time to name their cell therapy startup, Houston life science innovators simply had to look to their calendar.

“I would argue that March is the best month in Houston,” Sarah Hein tells InnovationMap. “We started talking about putting this company together during COVID, so we were outside a lot. And we actually got together in March.”

That’s why the CEO and her co-founders Max Mamonkin and Malcolm Brenner decided to name their company March Biosciences.

It's a fresh, unstuffy name for a startup that has an innovative take on cancer immunotherapy. Their lead asset is an advanced cellular therapy known as MB-105, an autologous CD5 CAR T cell therapy. For patients with T-cell lymphoma and leukemia who have failed all currently available lines of therapy, the prognosis is understandably extremely poor. But in a phase one study, MB-105 has been proven to safely treat those patients. The phase two study is expected to begin in the first half of 2024.

Hein met Mamonkin at the TMC Accelerator for Cancer Therapeutics (ACT), at which the alumna of Resonant Therapeutics and Courier Therapeutics was an entrepreneur in residence.

“It's a perfect example of the opportunities here in Houston where you can go from bench to bedside, essentially, in the same institution. And Baylor has been particularly good at that because of the Center for Cell and Gene Therapy,” says Hein.

The serial entrepreneur first came to Houston as a PhD student in molecular and cellular biology at Baylor College of Medicine, but during her studies she became excited by the startup ecosystem in her new hometown. After earning her degree, she became a venture fellow at the Mercury Fund. Her experience in both science and business made her an ideal candidate to take March Biosciences to the next level.

In September, the company announced that it formed a strategic alliance with CTMC (Cell Therapy Manufacturing Center), a joint venture between MD Anderson Cancer Center and National Resilience.

“Our unique risk-sharing model allows us to collaborate with organizations like March Biosciences to accelerate the development and manufacture of innovative cell therapies, like MB-105, and bring them into the clinic with a consistent and scalable manufacturing process,” said CTMC’s CEO, Jason Bock in a press release.

The partnership “has allowed us to move really quickly,” Hein says.

That’s because what CTMC does uniquely well is take early stage companies like March Biosciences and advance them to a state that’s ready for manufacturing in a short time, around 18 months, says Hein.

According to Hein, March Biosciences’ success is a testament to Houston and its world-class medical center.

“It’s a great example of the opportunities you see here in Houston, where we have a technology that was developed by brilliant scientists here in Houston and we can pull together the resources that we need to take it to the next level,” Hein says. "Working with partners here in Houston, we have all the pieces and the community rises to the occasion to support you.”

Energy tech startup secures $20M series B, plans to expand platform

money moves

A Houston startup has raised $20 million in its latest round of funding in order to accelerate its energy analytics and grid decarbonization technology.

Amperon Holdings Inc. announced today that it closed its series B round at $20 million. Energize Capital led the round and the D. E. Shaw group, Veriten, and HSBC Asset Management, an existing investor, joined in on the round. Additionally, two of Amperon's early customers, Ørsted and another strategic utility partner, participated in the series B, which brought Amperon’s total funding to $30 million.

The fresh funding will support the company in evolving its platform that conducts electricity demand forecasting to a comprehensive data analytics solution. Amperon's solution has an opportunity to really impact the industry's "increasingly turbulent power grids worldwide" among climate change and rapid adoption of variable energy resources, like wind and solar, the company explains in a news release about its raise.

“The energy transition is creating unprecedented market volatility, and Amperon is uniquely positioned to help market participants better navigate the transitioning grid – both in the U.S. and as we expand globally,” Sean Kelly, CEO and co-founder of Amperon, says in the release. “We've already established ourselves as the premier provider of electricity demand forecasting software. With this funding, we are poised to leverage our cutting-edge AI models to enable customers to unlock more value from data and asset optimization, spanning from on-site solar to commercial load management with backup generation and microgrid deployment.”

With the round, Energize Capital Partner Tyler Lancaster joins the Amperon board of directors.

“Today’s electricity grid is facing uniquely modern challenges as we work to rapidly transform our energy assets and decarbonize our economy,” he says in the release. “To facilitate the energy transition – a multitrillion-dollar market opportunity — we need more software tools custom-built to handle the complexities of our evolving energy markets.

"Amperon’s AI-powered analytics platform is exactly that, providing the accuracy and sophistication necessary for energy players across the value chain to manage their energy use and streamline our collective pathway to net-zero," he continues. "After getting to know Sean and the Amperon team since inception, Energize is thrilled to officially partner with them as a lead investor in this funding.”

In the past two years, Amperon reports that it grew revenue by five times, as well as quadrupled its team. The company was founded in 2017 and raised its $7 million series A last year.

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This article originally ran on EnergyCapital.