The HTX TechList — launching August 13 — will help connect the dots in Houston's sprawled and burgeoning innovation ecosystem. Getty Images

With a city as diverse and sprawling as Houston, the local innovation ecosystem could stand to benefit from a platform that connects all the dots virtually. So, that's exactly what Houston Exponential created.

HX — a nonprofit dedicated to promoting innovation in Houston — is launching HTX TechList August 13, and the platform will consist of profiles for startups, investors, startup development organizations, and corporations and will act as both a database as well as a forum for innovators to interact.

"The problem we've been solving for such a long time has been [not having] dependable data that you can rely on," says Serafina Lalany, chief of staff at HX. "We're taking responsibility for the curation for it and the quality assurance of it."

The fact of the matter is there's no one source for data and information on startups in Houston. While platforms like Crunchbase and Pitch Book exist — and the HTX TechList will factor in their data — they can have costly memberships and be far from complete, since they only represent venture capital-backed startups.

"For the first time ever, you're pulling up a startup page and you're seeing all their fundraising history, the SDOs they're a part of, a blurb of what they're working on, and, the thing I'm most excited about is, their tags," Lalany says, adding that there's over 2,000 tags. "It makes the whole thing super searchable."

Lalany emphasizes that accuracy is HX's goal, and the organization has a data team to help to ensure validity. After launch, the emphasis will be on calling Houston innovators to create accounts for themselves and their companies. HX's next hire will likely be for a marketing person, Lalany mentions.

The technology has been white labeled from Israel's Startup Nation Central, which launched Israel Startup Finder in 2017.

"Israel, a couple years ago, was also an emerging ecosystem," says Lalany, explaining that the country wanted to work toward global attention. Meanwhile, she continues, "Houston has access to global markets, but there's been an misconception that innovation wasn't happening here."

The HX team has been working with Startup Nation Central for a while and been training on the platform since January, which has included a buildout of 300 profiles for the site. The TechList will launch on August 13 with a free virtual event featuring Mayor Sylvester Turner, Israel's Startup Finder team, and several. Houston innovators. (Note: InnovationMap is a media partner for the event.)

"When we were thinking about the launch event and just the sheer number of virtual events that happen now, we wanted to be sure that whatever we produce is of absolute value to our audience — the founders," Lalany says.

The event, which has registration open online, will feature breakout rooms focused on topics that are important to Houston founders:

  • Early stage investment
  • Building your team
  • How to pitch to the press
  • Landing an enterprise customer
  • Opportunity in Houston
  • Resources for founders of color

While the idea for the platform has been considered for years at HX — even in its early days, the need for the HTX TechList has been enhanced in light of the COVID-19 pandemic, Lalany says.

"The world changed in March, and our mission has become realized even more profoundly than before. Our mission has always been to help connect the dots in Houston — it's such a large city, and outsiders are always overwhelmed," she says. "Once we went digital, we were able to do 10 times as much of the curation function that we did pre-pandemic. It's increased a lot of our efficiency."

One-stop shop

Screenshot courtesy of HX

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European spacecraft developer expands to Houston with U.S. business, new lab

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European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.