Looking for a job? These 2023 Houston Innovation Awards finalists are hiring

calling all applicants

Want to work for one of the top startups in Houston? Some of the best in Houston are hiring. Photo by Tima Miroshnichenko from Pexels

More than half of this year's startup finalists in the Houston Innovation Awards are hiring — who's looking for a job at one of the best startups in Houston?

When submitting their applications for the 2023 Houston Innovation Awards, which is taking place November 8 at Silver Street Studios, every startup was asked if it's hiring. Twenty-seven of the 35 startup honorees said yes, ranging from over 20 to just one positions open at each company.

Click here to secure your tickets to see which of these growing startups win.

Here's a look at which of the top startups in Houston are seeking new team members.

Double-digit growth

When it comes to the awards finalists looking to scale their team by 10 or more new hires, five finalists are growing rapidly.

Medical practice software platform RepeatMD, fresh off a $40 million raise — which included participation from Houston-based Mercury — is reportedly growing its team. The company, which has 115 employees already, is looking for over 20 new hires.

Female-owned business Feelit Technologies, which is using nanotechnology for preventive maintenance to eliminate leaks, fires and explosions, increase safety and reduce downtime, has 50 employees, and only three of which are in Houston – for now. The company hopes to grow its team by 12 to 15 employees in Houston alone.

Square Robot, an energy industry-focused robotics company that recently grew its presence in Houston, is hiring 10 to 30 new team members. It has 24 employees already in Houston.

Solugen, an alternative chemicals business, has around 140 of its 200 employees in Houston. The company, which has raised over $600 million to date, is hiring an additional 10 to 15 new hires.

Additionally, Blue People, also a finalist in last year's awards, is hiring 25 new employees. The company was founded in 2015 in Mexico and relocated its primary operations to Houston in 2020. Blue People, which develops software innovation for its clients, has over 150 employees — 10 of whom, including C-level executives, are based in Houston. Some of the company's new hires will be based in town.

Steady growth

Four Houston startups are hiring within the six to 10 team member range — all with fairly significant employee counts already.

A finalist in last year's awards too, Venus Aerospace, a hypersonics company on track to fly reusable hypersonic flight platforms by 2024, is again growing its team. With 48 on-site employees and 23 working remotely, Venus's team will add another five to 10 employees.

Syzygy Plasmonics, a deep decarbonization company that builds chemical reactors designed to use light instead of combustion to produce valuable chemicals like hydrogen and sustainable fuels, has 112 employees in Houston and plans to hire another eight to its team.

Lastly, Fervo Energy, which recently raised $10 million, has 63 full-time employees (34 in Houston, 29 outside of Houston) and looking to hire seven more.

Seeking selectively

The following awards finalists are looking to grow their teams by just a handful or so — between one and five — of new hires:

  • ALLY Energy, helping energy companies and climate startups find, develop, and retain great talent.
  • CaseCTRL, an AI-powered surgery scheduling and coordination software for optimized procedures.
  • CellChorus, using AI to evaluate immune cell function and performance to improve the development and delivery of therapeutics.
  • FluxWorks, making frictionless gearboxes for missions in any environment.
  • Helix Earth Technologies, decarbonizing the built environment and heavy industry.
  • Hope Biosciences, a clinical stage biotechnology company focused on the development and delivery of adult stem cell based therapeutics.
  • Innovapptive, empowering the deskless workers in operations, maintenance and warehouses by unlocking the power of SAP through mobility.
  • INOVUES, re-energizing building facades through its non-invasive window retrofit innovations, making building smarter, greener, and healthier for a better and sustainable future.
  • Koda Health, , a tech-enabled care coordination service to improve serious illness care planning and drive savings for value-based care at scale.
  • Molecule, an energy/commodity trading risk management software that provides users with an efficient, reliable, responsive platform for managing trade risk.
  • Rhythm Energy, 100 percent renewable electricity service for residential customers in Texas.
  • Starling Medical, bringing the future of a proactive and predictive home-based healthcare system to patients today through passive AI powered at home urine screening.
  • Taurus Vascular, pioneering a new era of aortic aneurysm treatment by developing minimally invasive catheter solutions to drive better long-term patient outcomes.
  • Tierra Climate, decarbonizing the power grid faster by helping grid-scale batteries monetize their environmental benefits and change their operational behavior to abate more carbon.
  • UpBrainery Technologies, an innovative educational technology company that provides personalized and adaptive learning experiences to learners
  • Utility Global, a technology company converting a range of waste gases into sustainable hydrogen and syngas.
  • Voyager Portal, helping commodity shippers identify root causes of demurrage, reduce risk and streamline the entire fixture process.

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Rice University and Houston Methodist have teamed up to fund life science research — and more Houston innovation news you need to know. Image courtesy of Rice

Houston health startups make most promising list, clean energy co. wins award, and more news

short stories

Houston startup news has still been full speed ahead, despite the year coming to a close, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, a climatetech leader steps down, two digital health companies have been recognized internationally, and more.

Two Houston startups land on most-promising health tech list

Houston has some representation on this year's Digital Health 150. Image via CB Insights

CB Insights released The Digital Health 150, an annual ranking of the 150 most promising digital health startups in the world, last week and two Houston companies made the cut. Houston-based companies Koda Health and Starling Medical were two of the eight Texas startups on the list.

Founded in 2020, Koda Health is a B2B Enterprise SaaS solution that guides patients through the process of proactive healthcare planning and document authentication. The company has been expanding its service across the country this year following a seed round of funding in February.

"Each year, 150 winners are selected from a pool of over 13,000 companies," Koda's CEO and Co-Founder Tatiana Fofanova tells InnovationMap. "Honorees have quickly become industry titans and household names, so we were honored — and frankly, surprised! — to be recognized in this year's group of honorees.

"I've personally taken inspiration from the Digital Health 150 for years now ± these are people and companies we've emulated and aspired to — so to see the Koda Health logo on there was incredibly affirming," she continues.

Starling Medical is using AI and telehealth enabled medical devices to enable millions with bladder dysfunctions to be able to urinate safely and conveniently again. The company has been named most promising by the Rice Alliance as well, and a top 10 company by MassChallenge.

Optellum, a United Kingdom-based company focused on lung cancer diagnostics, also made the list. They have their United States-based operations in Houston. Additionally, seven startups on the list — Babyscripts, Cerebriu, Iterative Health, Kintsugi, Mindtrace, Redox, and Lightbeam — have ties to TMC.

This is the fourth annual Digital Health 150, and this new cohort has already raised approximately $5.6 billion in aggregate funding across 378 deals since 2017, according to CB Insights.

Houston startup snags win at the 'Oscars' of energy industry

Syzygy Plasmonics was recognized for being an outstanding energy transition company. Photo via LinkedIn

At the 24th annual Platts Global Energy Awards gala, S&P Global Commodity Insights honored industry excellence across 19 categories. Described as the "Oscars" of energy, the program "recognizes corporate and individual innovation, leadership, and performance in the energy and petrochemicals industry," according to a news release.

"We are proud to recognize the leadership and innovation of this year's finalists and winners of the Platts Global Energy Awards," says Saugata Saha, president of S&P Global Commodity Insights, in the release. "These companies have demonstrated a commitment to excellence while serving customers and enabling a balanced energy transition, a key area of focus for the industry and our teams at S&P Global Commodity Insights."

Houston-based alternative energy company, Syzygy Plasmonics, took home a win for the "Energy Transition Technology of the Year Award." Syzygy, which recently raised a $76 million series C round, has a technology that harnesses the power of light to energize chemical reactions — rather than the traditional process that is fueled by heat. The Syzygy approach reduces feedstock waste and produces fewer emissions when powered by renewable electricity.

Greentown Labs CEO steps down

In her capacity as Greentown Labs CEO, Emily Reichert cut the ribbon on Greentown Houston over a year and a half ago. Photo by Lee Bond/Greentown Labs

The leader of Somerville, Massachusetts-based Greentown Labs, which has its only other location in Houston, has stepped down after a decade at the helm of the climatetech incubator.

In an email to the Greentown Labs community, Emily Reichert confirmed that she has stepped down as CEO and will remain involved as "CEO Emeritus." The organization's CFO, Kevin Taylor, has picked up more leadership responsibilities in the interim.

"As I hand the baton off to the next leader of Greentown Labs, I’m confident in our community’s ability to continue making an enormous impact deploying climatetech solutions and our team’s ability to continue growing Greentown to be an ever-more-impactful space for climatetech entrepreneurs and collaborators," Reichert says in the email.

Rice backs new research collaborations with Houston Methodist

Rice University and Houston Methodist have again teamed up to support life science research. Photo via rice.edu

Two Houston organizations — Rice University and the Houston Methodist Academic Institute — have created a seed grant program and awarded grants for research in robotics, imaging, cardiovascular bioengineering, and more. Twenty multi-year projects will be supported by both Houston Methodist and Rice, according to a news release.

It's the third collaborative program between the two organizations in less than two years.

“Our collaborations with Houston Methodist will impact human health and wellness, foster new research opportunities and advance our understanding of diseases," says Rice Provost Amy Dittmar in a news release.

The projects within the nursing category have not been announced, but the awards for the other categories have been named online.

Want to work for one of the top startups in Houston? These ones are hiring. Photo by Tima Miroshnichenko from Pexels

Here's which of the InnovationMap Awards finalists are hiring

growing biz

After scouring Houston for the best of the Houston innovation ecosystem and evaluating dozens of companies, InnovationMap has announced the finalists in its inaugural awards. But which of these companies are growing their teams?

Turns out, almost all of them have open positions — some planning to double their teams over the next year. In fact, the 28 companies that make up our cohort of finalists are looking for over 250 new employees — some have these positions open now and others are seeking these new team members over the next 12 months.

Let's look at how many new hires these top startups are looking for.

Biggest gains

The InnovationMap Awards finalist with the loftiest hiring goal is Liongard, which is a finalist in the People's Choice: Startup of the Year category. Liongard — a platform that helps IT companies automatically discover, document, and audit their customers' IT systems — is looking to fill 70 positions over the next year. The company, founded in 2015, has just over 100 employees now.

The startup finalist with the second highest hiring goals is Nanotech, a material science company with a mission to fireproof the world and reduce energy consumption. Nanotech is looking to hire over 40 new employees in the next 12 months, which would almost triple its current staff of 15. Founded in 2019 by Mike Francis, the company is a finalist in both the Energy Transition and People's Choice categories.

Another People's Choice finalist, GoCo, and its all-in-one employee management platform, is currently looking to grow its team by adding 20 new employees to its staff of 53. The company was founded in 2015 and has since raised over $12 million in VC funding.

Also looking to grow their team by 20 new hires is Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools. The company, co-founded by Carolyn Rodz, is up for an award in the BIPOC-Founded, Female-Founded, and People's Choice categories.

GoExpedi, whose founder and CEO Timothy Neal is a finalist in the Top Founder Under 40 category, currently has 17 positions open at the moment and is looking to add those new hires into its team of over 150 employees. The e-commerce, supply chain, and analytics company is streamlining procurement for industrial and energy MRO (maintenance, repair and operations).

While Female-Founded Business finalist RingOn — a wearable GPS tracker that is also a panic button that's designed for school kids and with an impact-driven mission of ending child trafficking — is only currently looking for six new hires, the company is expecting to hiring another 15 new employees next year. Right now, the company's employee count is at three.

Steady growth

A few of the awards finalists are sporting hiring goals in the seven to 12 new staffers range. Space Tech finalist NANCO Aero, which is developing package- and person-carrying air vehicles, is hiring a dozen new employees — a big goal considering the company currently has just four employees.

Enercross LLC, automation software for the energy industry, is a finalist in the Energy Transition category and is looking to add 11 new people to its team of 42. Meanwhile Sports Tech finalist sEATz — a mobile ordering and delivery platform for food, drinks, and merchandise at large events — is looking to about double its team of 10 over the few months.

Health Tech finalist Medical Informatics Corp. is the creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions. The company has seven open positions to grow its team of 36.

Seeking selectively

The following InnovationMap Awards finalists are looking to grow their teams with between two and six new hires:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • CaseCTRL — using artificial intelligence and automation to streamline surgical scheduling.
  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Cheers Health — creating products that are designed to support your liver and help you feel better after consuming alcohol.
  • Cognitive Space — providing a scalable satellite constellation management solution to the space industry.
  • Data Gumbo — creator of an interconnected industrial smart contract network secured and powered by blockchain.
  • DonateStock — simplifying the process of donating stock and helping nonprofits solicit, process, and manage stock donations.
  • FitLift — a wearable device and mobile platform that tracks motion and gives real-time feedback on lifting technique, allowing trainers, and athletes to drive results.
  • LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds
  • Molecule Software — creator of a leading cloud-native energy trading software.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • Saranas — creator of the Early Bird, the first and only FDA-approved bleed detection system for endovascular procedures.
  • Starling Medical — using AI and telehealth enabled medical devices to enable millions with bladder dysfunctions to be able to urinate safely and conveniently again.
  • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.
  • Zibrio Inc. — a fall prevention solution that empowers both clinicians and patients for better outcomes.

Find out which of these employers take home the win at the September 8 event at The Cannon - West Houston. Honorees, sponsors, judges, and their guests will celebrate in person, and the rest of the innovation community is invited to tune in to the livestream. Click here to RSVP.

Sponsorships are still available! If you are interested in partnering with InnovationMap as a sponsor of this event, send an email to awards@innovationmap.com.

And the finalists for the inaugural InnovationMap Awards are... Graphic via Gow Media

InnovationMap names 28 Houston startup finalists for inaugural awards

who will take home the win?

Who are Houston's rising stars across energy transition, sports tech, health, and more? InnovationMap set out on a quest to discover that for its inaugural awards. Ahead of the September 8 event, we're revealing the finalists across all categories.

Eight judges evaluated over 100 applications across eight categories for the 2021 InnovationMap Awards presented by Techwave. This year's judges included: JulianaGaraizar, head of the Houston incubator and vice president of innovation at Greentown Labs; Alex Gras, managing director at The Cannon; Rajasekhar Gummadapu, co-founder and CEO of Techwave; Natalie Harms, editor of InnovationMap; Serafina Lalany, interim president at Houston Exponential; Jon Nordby, managing director at MassChallenge; Emily Reiser, senior manager of innovation community engagement at the Texas Medical Center; and Grace Rodriguez, CEO and executive director of Impact Hub Houston.

The winners will be announced and celebrated — along with this year's previously announced Trailblazer Award recipient, Barbara Burger of Chevron Technology Ventures — at the September 8 event at The Cannon - West Houston. Honorees, sponsors, judges, and their guests will celebrate in person, and the rest of the innovation community is invited to tune in to the livestream. Click here to RSVP.

Sponsorships are still available! If you are interested in partnering with InnovationMap as a sponsor of this event, send an email to awards@innovationmap.com.

Without further adieu, here are this year's finalists:

BIPOC-Founded Business Finalists

The finalists for the BIPOC-Founded Business Award category, honoring innovative tech companies founded or co-founded by BIPOC representation, are:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
  • LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds
  • Molecule Software — creator of a leading cloud-native energy trading software.

Female-Founded Business Finalists

The finalists for the Female-Founded Business Award category presented by Veritex Community Bank, honoring innovative tech companies founded or co-founded by women, include:

  • DonateStock — simplifying the process of donating stock and helping nonprofits solicit, process, and manage stock donations.
  • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • RingOn — wearable GPS tracker that is also a panic button that's designed for school kids and with an impact-driven mission of ending child trafficking.
  • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.
  • Zibrio Inc. — a fall prevention solution that empowers both clinicians and patients for better outcomes.

Health Care Business Finalists

The finalists for the Health Care Business Award category presented by Gray Reed, which honors health care businesses with an innovative solution within life sciences, include:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • Medical Informatics Corp. — creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions.
  • Saranas — creator of the Early Bird, the first and only FDA-approved bleed detection system for endovascular procedures.
  • Starling Medical — using AI and telehealth enabled medical devices to enable millions with bladder dysfunctions to be able to urinate safely and conveniently again.

Energy Transition Business Finalists

The finalists for the Energy Transition Business category, which honors energy business with innovative solutions within renewables, climatetech, clean energy, and beyond, are:

  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Data Gumbo — creator of an interconnected industrial smart contract network secured and powered by blockchain.
  • Enercross LLC — automation software for the energy industry.
  • Nanotech — a material science company with a mission to fireproof the world and reduce energy consumption.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • Renewell Energy — converting idle oil and gas wells into flexible energy storage.

Sports Tech Business Finalists

The finalists for the Sports Tech Business category, which is honoring a sports tech business with an innovative solution within sports are:

  • FitLift — a wearable device and mobile platform that tracks motion and gives real-time feedback on lifting technique, allowing trainers, and athletes to drive results.
  • Mainline — an esports tournament management system, tournament organizer, and event production company.
  • sEATz — a mobile ordering and delivery platform for food, drinks, and merchandise at large events.

Space Tech Business Finalists

The finalists for the Space Tech Business category, which is honoring an aerospace business with an innovative solution within space exploration. are:

  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Cognitive Space — providing a scalable satellite constellation management solution to the space industry.
  • NANCO Aero — developing package- and person-carrying air vehicles.

Top Founder Under 40 Finalists

The finalists for the Top Founder Under 40 category, which honors an innovative founder younger than 40 by Sept. 8, 2021, are:

  • Pamela Singh of CaseCTRL — using artificial intelligence and automation to streamline surgical scheduling.
  • Timothy Neal of GoExpedi — an e-commerce, supply chain, and analytics company that is streamlining procurement for industrial and energy MRO (maintenance, repair and operations).
  • Kim Roxie of LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds.
  • Emma Fauss of Medical Informatics Corp. — creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions.
  • Emily Cisek of The Postage — a legacy planning platform using tech to make afterlife decision making easier.

People’s Choice: Startup of the Year Finalists

The finalists for the People's Choice: Startup of the Year category, which will each present a 60-second live elevator pitch at the event on September 8, are:

    • Cheers Health — creating products that are designed to support your liver and help you feel better after consuming alcohol.
    • GoCo — all-in-one employee management platform.
    • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
    • Liongard — a platform that helps Information Technology companies automatically discover, document, and audit their customers' IT systems.
    • Nanotech — a material science company with a mission to fireproof the world and reduce energy consumption.
    • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
    • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.

    Here's which life science companies — in Houston and beyond — are ones to watch. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

    Houston organization names 10 most promising life sciences startups

    ones to watch

    Last week, the Rice Alliance for Technology and Entrepreneurship gathered over 1,000 life science experts and attendees virtually for thought leadership as well as 40 company presentations.

    The three-day 2020 Virtual Texas Life Science Forum was made possible through a partnership with BioHouston and support from Texas Medical Center and Insperity. At the close of the summit, several companies were recognized with awards.

    Houston-based Starling Medical won the Michael E. DeBakey Memorial Life Science Award, established by BioHouston in honor of the groundbreaking Houston cardiovascular surgeon. The digital health device company is revolutionizing severe bladder dysfunction management with artificial intelligence.

    Every year at the forum, the Rice Alliance names its 10 most promising companies working on developing innovative solutions in medical devices, digital health, diagnostics, pharmaceuticals, and therapeutics. This year, Brad Burke, managing director of the Rice Alliance, says they had more applications to present than ever before. Additionally, the presenting companies — about half of which are Houston-based — have already raised more than $275 million in funding.

    The 2020 most-promising life science companies, which were chosen by investors and presented by the Greater Houston Partnership, were:

    Droice Labs

    Image via droicelabs.com

    New York-based Droice Labs, is an artificial intelligence and big data company matches patients to therapies and delivers personalized medicine at scale while reducing costs.

    "Our cutting-edge technology seamlessly integrates into clinical workflows, and we continue to evolve unique and powerful applications for our clients and the patients they serve," reads the company's website.

    SFA Therapeutics

    Image via sfatherapeutics.com

    Based in Jenkintown, Pennsylvania, SFA Therapeutics is developing oral drugs for treating conditions of chronic inflammation that have the potential to change the practice of medicine. The company has treatments for Psoriasis, Liver Cancer (Hepatitis B, NASH and HCC), Ophthalmic Diseases, Cytokine Release Syndrome- a side effect in CAR-T, Prevention of Relapse/Recurrence in Leukemias, and other diseases.

    Hummingbird Bioscience

    Photo via jlabs.jnjinnovation.com

    Hummingbird Bioscience, based in Houston's JLABS @ TMC, is tackling challenging targets that play a key role in disease yet have not been effectively drugged. The company has worked on 12 therapies in various stages of development, four of which have the potential to revolutionize their fields.

    "At Hummingbird, we believe that modern approaches to systems biology and data science can overcome the challenges of classical methods of therapeutics discovery, and profoundly improve the way we deliver new transformative medicines," reads the company website.

    CaseCTRL

    Image via casectrl.com

    Houston-based CaseCTRL is empowering surgeons with a management platform with software-as-a-service technology that uses AI and logistics to lower operational costs and simplify surgical planning.

    "The surgical scheduling process is frustratingly stuck in the past: siloed, paper-based, and too dependent on single schedulers," reads the website. "Surgeons are stressed and overworked. They need a better way to communicate their complex surgical plans, timelines and resource needs."

    Perimeter Medical

    Image via perimetermed.com

    Perimeter Medical, based in Dallas, is driven to transform cancer surgery with advanced, real-time, ultra high-resolution imaging tools including AI to address areas of unmet medical need.

    "Perimeter is dedicated to providing solutions that drive better patient care and lower healthcare costs by providing critical information, during clinical procedures," reads the website.

    Studio Bahria

    Image via studiobahia.org

    San Antonio-based Studio Bahia, is developing an accessible model for therapy in addressing mental health crises from the pandemic through virtual reality.

    "We are in production of our first two therapies for release in the 4th quarter of 2020. Studio Bahia clients include corporate, retail, and institutional partners who purchase our headsets for $25 in providing mental health therapies and wellness tools to employees, executives, and patients," reads the company's website.

    Tvardi Therapeutics

    Photo via Getty Images

    Tvardi Therapeutics, based in Houston, is a clinical-stage biopharmaceutical company focused on the development of a new class of breakthrough medicines for diverse cancers and chronic inflammatory and fibrotic diseases.

    "Tvardi is focused on the development of orally delivered, small molecule inhibitors of STAT3, a key signaling molecule positioned at the intersection of many disease pathways," reads the website.

    Koda Health

    Image via kodahealthcare.com

    Koda Health, Houston, uses AI to help guide difficult conversations in health care, starting with end-of-life care planning.

    "You're entitled to protect the healthcare decisions that matter most to you and your family," the company's website promises. "Koda creates Care Plans to ensure that you get the medical care you want."

    Immuno Genesis

    Photo via Getty Images

    Houston-based ImmunoGenesis is a clinical-stage biotechnology company developing therapeutics to catalyze effective immune responses in immunologically "cold" cancers such as prostate, colorectal, and pancreatic.

    "Compared to existing immunotherapy drugs, we believe this antibody will both provide more consistent benefit for patients with immune-infiltrated tumors, and, for the first time, will also benefit patients with immune 'cold' cancers," says founder Dr. Michael A. Curran in a press release announcing the company's grant from the Cancer Prevention and Research Institute of Texas.

    Ictero Medical

    Image via Getty Images

    Ictero Medical, based in Houston, is developing the first minimally invasive cryoablation solution to treat patients with gallstone disease. Ictero Medical has created a minimally invasive treatment, called The CholeSafe System, that uses cryoablation to defunctionize the gallbladder without having to remove it.

    These are the 10 finalists heading to MassChallenge's virtual awards program next month. Photo courtesy of MassChallenge

    MassChallenge Texas names its top 10 companies in its Houston cohort

    best of the rest

    Boston-based MassChallenge has named its top picks from its second Houston cohort ahead of its awards event. This year's programming, due to the pandemic, was held completely online.

    "Great entrepreneurs don't let a crisis go to waste: this cohort was assembled from virtually every industry across 13 different countries and through the twists and turns, their passion became a beacon for the future," says Jon Nordby, managing director of MassChallenge Texas in Houston. "These top startups represent the best qualities of all of us: resilient, ingenious, and able to push ourselves further than we think we are capable. They embody the entrepreneurial spirit that brings hope and progress to society."

    The 10 companies — which represent the top 18 percent of the cohort — will now compete in a final round of judging for up to $250,000 in equity-free cash prizes. The winners will be revealed at the 2020 MassChallenge Virtual U.S. Awards, which will be held online.

    The 2020 MassChallenge Texas in Houston top 10 finalists are:

    • B2B Pay, based in Helsinki, Finland, is a fintech startup with a multi-bank platform.
    • FloodFrame, based in Richmond just outside of Houston, is a self-deploying flood protection system that can be easily installed to existing houses.
    • Healium, based in Columbia, Missouri, is an extended reality device created for self-management of anxiety.
    • Houston-based Integricote uses nanotechnology research that originated from the University of Houston in the treatment and fortification of materials like wood and concrete.
    • Ozark Integrated Circuits Inc., based in Fayetteville, Arkansas, specializes in problem solving using technology and software in the harshest environments – from jet engines to earth orbit.
    • Houston-based PATH EX Inc. is focused on the rapid diagnosis and treatment of sepsis through a pathogen extraction platform.
    • PREEMIEr Diagnostics, based in Southfield, Michigan, created a way to identify which premature infants need an adjustment to their glucose levels to prevent them from losing vision.
    • Scout Inc., based in Alexandria, Virginia, is developing the first commercial in-space satellite inspection service.
    • Sunnydale, California-based Sizzle is using artificial intelligence to automatically create gaming highlights for the billion gaming viewers.
    • Starling Medical, based in Houston, has tapped into tech to optimize urinary catheter for patients with neurogenic bladder dysfunction.

    The 54-company cohort, which is the second based in Houston since the program's launch last year, was challenged early on — much like the other MassChallenge cohorts — to pivot to virtual acceleration over the four-month experience.

    Robert Pieroni, director of Economic Development for Central Houston, which was part of the group that worked to bring MCTX to Houston, says he sees a need for this type of accelerator now more than ever.

    "MassChallenge's work sources ground-breaking ideas from around the world and invites them into an inclusive village surrounded by a network of tools, resources, and opportunities that help founders accelerate and scale their business to solve humankind's boldest challenges head-on," he says. "The addition of virtual and the rise of distributed teams in response to the pandemic will make it easier for startups to launch and build businesses anywhere."

    MassChallenge's Houston cohort will be one of a few featured at the virtual awards event on October 22 at 4 p.m. Headliners for the event include Arianna Huffington, founder and CEO of Thrive Global, and Linda Pizzuti Henry, managing director of the Boston Globe, and Chris Denson of Innovation Crush will be the host. For more information about the event and to register, visit the MassChallenge website.

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    Rice lab cooks up breakthrough 'living pharmacy' research for potential cell therapy treatment

    biotech innovation

    Rice University’s Biotech Launchpad has created an electrocatalytic on-site oxygenator, or ecO2, that produces oxygen intended to keeps cells alive. The device works inside an implantable “living pharmacy,” which the Rice Biotech Launch Pad team believes will one day be able to administer and regulate therapeutics within a patient’s body.

    Last week, Rice announced a peer-reviewed publication in Nature Communications detailing the development of the novel rechargeable device. The study is entitled “Electrocatalytic on-site oxygenation for transplanted cell-based-therapies.”

    How will doctors use the “living pharmacy?” The cell-based therapies implanted could treat conditions that include endocrine disorders, autoimmune syndromes, cancers and neurological degeneration. One major challenge standing in the way of bringing the technology beyond the theoretical has been ensuring the survival of cells for extended periods, which is necessary to create effective treatments. Oxygenation of the cells is an important component to keeping them alive and healthy and the longer they remain so, the longer the therapeutics will be helpful.

    Other treatments to deliver oxygen to cells are ungainly and more limited in terms of oxygen production and regulation. According to Omid Veiseh, associate professor of bioengineering and faculty director of the Rice Biotech Launch Pad, oxygen generation is achieved with the ecO2 through water splitting that is precisely regulated using a battery-powered, wirelessly controlled electronic system. New versions will have wireless charging, which means it could last a patient’s entire lifetime.

    “Cell-based therapies could be used for replacing damaged tissues, for drug delivery or augmenting the body’s own healing mechanisms, thus opening opportunities in wound healing and treatments for obesity, diabetes and cancer, for example. Generating oxygen on site is critical for many of these ‘biohybrid’ cell therapies: We need many cells to have sufficient production of therapeutics from those cells, thus there is a high metabolic demand. Our approach would integrate the ecO2 device to generate oxygen from the water itself,” says Jonathan Rivnay of Northwestern University, who co-led the study with Tzahi Cohen-Karni of Carnegie Mellon University (CMU).

    The study’s co-first authors are Northwestern’s Abhijith Surendran and CMU’s Inkyu Lee.

    Northwestern leads the collaboration with Rice to produce therapeutics onsite within the device. The research supports a Defense Advanced Research Projects Agency (DARPA) cooperative agreement worth up to $33 million to develop the implantable “living pharmacy” to control the human body’s sleep and wake cycles.

    “This breakthrough technology has the potential to reshape the landscape of disease treatment and the future of research and development in the field of cell-based therapies. We are working toward advancing this technology into the clinic to bring it one step closer to those in need,” says Veiseh.

    Houston corporate venture leader calls for collaboration across sustainable fuel, innovation community

    HOUSTON INNOVATORS PODCAST EPISODE 212

    When it comes to the future of aviation — namely, making it more sustainable, a rising tide lifts all boats. Or, in this case, planes.

    Andrew Chang, managing director of United Airlines Ventures, explains that working together is the key for advancing sustainable aviation fuel, or SAF. That's why United Airlines started the Sustainable Flight Fund, a $200 million initiative with support from industry leaders, including Air Canada, Boeing, GE Aerospace, JPMorgan Chase, Honeywell, Aramco Ventures, Bank of America, Hawaiian Airlines, JetBlue Ventures, and several others.

    "We all recognize that we may compete in our core business, but with the importance of sustainable aviation fuel and given that it's an industry that doesn't exist — you can't compete for something that doesn't exist — let's collaborate and work together to explore technologies that can directly or indirectly support the commercialization and production of sustainable aviation fuel," he says on the Houston Innovators Podcast.

    Within United Airline Ventures, Chang's job is to find technology to invest in across the aviation industry spectrum — from SAF to digital technologies that will improve the United customer experience. This means working with startups and other organizations to find the best fit — and, because he's based in Houston, one of United's seven key hubs, this means knowing and interacting with local innovators.

    "The knowledge base and the capabilities are here — that's undebatable," Chang says of the Houston innovation ecosystem. "The next step is making sure we're accessing, promoting, collaborating, and learning from one another."

    Again, as Chang recognizes, collaboration is key to further developing the ecosystem, "so that we're not trying to solve the same problem in a vacuum," he explains.

    United Airlines recently signed an offtake agreement with Cemvita Factory, a Houston biotech startup that's working on SAF. Chang discusses this partnership on the show, as well as explaining how he works with other startups and what he's looking for.

    4 Houston life science startups secure over $40M in CPRIT funding

    cha-ching

    Four Houston bioscience startups have collected nearly $43 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT).

    Here’s a list of the four startups, the amount and purpose of each grant, and some background information about each company.

    Stingray Therapeutics

    CPRIT grant amount: $13,881,458

    Purpose of grant: Clinical trial to evaluate an immunotherapy known as SR-8541A for treatment of advanced or metastatic solid tumors.

    Company background: Stingray received a $2 million Small Business Innovation Research (SBIR) award in 2022. In conjunction with the award, Mohan Kaadige, a research associate professor at the Translational Genomics Research Institute, joined Stringray as the principal SR-8541A investigator.

    “I … believe we have great potential to alleviate cancer suffering in the near future with this exciting technology,” says Kaadige.

    March Biosciences

    CPRIT grant amount: $13,358,637

    Purpose of grant: Clinical trial to evaluate a T-cell immunotherapy (MB-105) for treatment of certain types of relapsed lymphoma.

    Company background: March Biosciences, a Baylor College of Medicine spinout, recently received $4.8 million in funding from Cancer Focus Fund, affiliated with Houston’s MD Anderson Cancer Center.

    “The breadth and quality of the support we are receiving from our local partners and institutions underscore Houston’s increasing prominence as a worldwide leader in cancer R&D and clinical research,” says Sarah Hein, co-founder and CEO of March Biosciences.

    Mongoose Bio

    CPRIT grant amount: $10,621,053

    Purpose of grant: Development of T-cell therapies targeting solid-tumor cancer.

    Company background: Mongoose founder Cassian Lee, a professor and researcher at MD Anderson, is a CPRIT scholar and a participant in Texas Medical Center Innovation’s 2023 Accelerator for Cancer Therapeutics.

    “Mongoose Bio is a first-rate example of the use of CPRIT funds to fund a disruptive cell gene therapy … therapeutic with deep roots and origins in Texas. This innovation will benefit patients with solid tumors not just in Texas but the rest of the world,” says CPRIT.

    FixNip

    CPRIT grant amount: $4,844,088

    Purpose of grant: Clinical study and manufacturing of a silicone implant that creates a soft, natural-looking nipple for women with breast cancer who’ve undergone post-mastectomy breast reconstruction. The clinical study will be done at MD Anderson.

    Company background: In conjunction with the CPRIT grant, FixNip is moving its headquarters from Israel to Houston. Austin-based CPRIT became aware of FixNip during a May 2022 trade trip to Israel by the organization’s CEO, Wayne Roberts.

    “Loss of nipple projection is the most pervasive problem across all currently existing nipple reconstruction solutions,” says FixNip.

    Aside from the grants for the four Houston startups, CPRIT handed out two grants for recruitment of two cancer researchers to Houston:

    • $6 million grant to recruit Dr. Leonido Luznik of Johns Hopkins University to the Baylor College of Medicine. Luznik’s research focuses on allogeneic blood and marrow transplantation (alloBMT), a treatment for blood cancers.
    • $1.99 million grant to recruit Swiss researcher Christina Tringides to Rice University. Tringides is working on a “groundbreaking” treatment for brain tumors, says CPRIT.
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