Boxes by Speak As One keep mental health tools feeling fresh, without overloading the user. Photo courtesy of Speak As One

Mental health apps are so alluring, but once you’ve recorded your two-week streak and things are feeling a little more organized, it can be hard to keep going. It’s hard enough to keep up with journaling and a great bedtime routine, and many lovely self-help tools also lose their effectiveness when the novelty wears off.

A smart company might harness that novelty as its hook — and an easily distracted self-helper won’t fall off the wagon. Like many other companies in the mental health space, Speak As One will work on a subscription model, but this one won’t languish, unused on a credit card statement. The service, which plans to launch during SXSW 2023, delivers boxes of tangible mental health tools, inspiration, games, and even sensory objects that act as a monthly nudge to try something new, and curiosity takes care of the rest.

A sample box included:

  • Stress balls with short inspirational phrases by MindPanda
  • An Emotional First Aid Kit containing advice for situations as they come up, like sleeplessness and feelings of inadequacy
  • Tiny colorful putties at different resistances by Flint Rehab
  • A notebook, and two books: Athlete Mental Health Playbook and 1000 Unique Questions About Me
  • Other small items

It’s more than packing and shipping out a few toys each month. The boxes are curated with help from a licensed therapist, who leaves a personal note along with tips on how to use the items inside and additional resources. There is one type of box right now that aims to “reduce anxiety, increase mindfulness, and promote peace and balance,” but for further customization (for $10 more), the team is working on boxes tailored to first responders, veterans, athletes, and people in “recovery.”

Speak As One emphasizes community stories in its branding outside the delivery box, and uses inspiration from “influencers” (less content creators and more so people who can embody a relatable story) to build the specialty boxes. The company’s YouTube channel shares dozens of interviews with founder Julie Korioth, a former board member for Austin’s SIMS Foundation, a well-respected mental health resource for members of the local music industry.

“With hundreds of millions of people struggling with mental health, and COVID making the issue much worse, society continues to ostracize those who openly discuss mental health issues,” said Korioth in a release. “I founded this company so we can change the way the world sees, discusses, and supports mental health. Our goal is to promote empathy, connectedness, acceptance, and thoughtfulness with an innovative toolkit that caters to specific needs."

In addition to offering a nudge, these boxes could make great care packages for a loved one who is feeling introspective or going through a significant life event. It is possible to buy gift boxes, if presentation is your thing, but it’d be just as easy to repackage a box that comes before the receiver ready to appreciate the items at home.

The cost of one box is manageable at $49.99 (especially considering the retail value of products included, which the sample box far exceed), but for many subscribers this adds up fast. Luckily, there is no pressure to continue a lengthy commitment — subscriptions last between one and six months, so users have plenty of time to reconsider and sit with the items that have already been delivered.“

The goal is to meet our audience at any phase of their mental health journey,” said Korioth. “We’re creating change and a global life-long support system for children and adults dealing with mental health challenges. We simultaneously highlight businesses, the tech community, athletes, and artists doing wonderful work in this space.”

The company plans to partner with corporations to connect with employees and provide boxes to individuals the company chooses, and will turn some content into session albums with sales proceeds dedicated to mental health research.

More information and links to preorder are available at speakasone.com.

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This article originally ran on CultureMap.

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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Luxury transportation startup connects Houston with Austin and San Antonio

On The Road Again

Houston business and leisure travelers have a luxe new way to hop between Texas cities. Transportation startup Shutto has launched luxury van service connecting San Antonio, Austin, and Houston, offering travelers a comfortable alternative to flying or long-haul rideshare.

Bookings are now available Monday through Saturday with departure times in the morning and evening. One-way fares range from $47-$87, putting Shutto in a similar lane to Dallas-based Vonlane, which also offers routes from Houston to Austin and San Antonio.

Shutto enters the market at a time when highway congestion is a hotter topic than ever. With high-speed rail still years in the future, its model aims to provide fast, predictable service at commuter prices.

The startup touts an on-time departure guarantee and a relaxed, intimate ride. Only 12 passengers fit inside each Mercedes Sprinter van, equipped with Wi-Fi and leather seating. And each route includes a pit stop at roadside favorite Buc-ee's.

In announcing the launch, founder and CEO Alberto Salcedo called the company a new category in Texas mobility.

“We are bringing true disruptive mobility to Texas: faster and more convenient than flying (no security lines, no delays), more comfortable and exclusive than the bus or train, and up to 70 percent cheaper than private transfers or Uber Black,” Salcedo said in a release.

“Whether you’re commuting for business, visiting family, exploring Texas wineries, or doing a taco tour in San Antonio, Shutto makes traveling between these cities as easy and affordable as riding inside the city."

Beyond the scheduled routes, Shutto offers private, customizable trips anywhere in the country, a service it expects will appeal to corporate retreat planners, party planners, and tourists alike.

In Houston, the service picks up and drops off near the Galleria at the Foam Coffee & Kitchen parking lot, 5819 Richmond Ave.. In San Antonio, it is located at La Panadería Bakery’s parking lot at 8305 Broadway. In Austin, the location is the Pershing East Café parking lot at 2501 E. Fifth St.

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This article originally appeared on CultureMap.com.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”