WalletHub ranks these Texas towns among the best for starting a business. Photo via Getty Images

When it comes to launching a business in Texas, you might want to look into the suburbs that surround the state's major metros.

Personal finance website WalletHub ranked the best and worst small towns to start a business — and the Lone Star State had plenty of suburbs making the top 400 in the list of more than 1,300 towns.

The report found that Georgetown as the best small city in Texas for starting a business. The website classifies a small city as one with a population of 25,000 to 100,000. The Austin suburb appears at No. 70 on the list overall, and No. 1 in Texas. It scored particularly well in the access to resources category (No. 26) and business environment category (No. 31).

To determine the best small cities for startups, WalletHub compared the business-friendly nature of more than 1,300 small cities across the country. Among the factors it examined were average growth in number of businesses, labor costs, and investor access.

Houston suburbs didn't manage to crack the top 200, but four were recognized amongst the rest of the best small busissiness towns:

  • Texas City , No. 202
  • Baytown, No. 267
  • Deer Park, No. 362
  • Conroe, No. 369

Washington, Utah, nabbed the top spot nationally, along with four other Utah cities in the top 10.

“Size matters when choosing a city in which to launch a startup. As many veteran entrepreneurs — and failed startups — understand well, bigger is not always better,” WalletHub says. “A city with a smaller population can offer a greater chance of success, depending on an entrepreneur’s type of business and personal preferences.”

Elsewhere in Texas, other highly ranked small cities in include:

  • Farmers Branch (Dallas-Fort Worth), No. 102
  • Pflugerville lands (Austin), No. 150
  • San Marcos (Austin), No. 181
  • West Odessa, No. 193
  • Leander (Austin), No. 250
  • Kyle (Austin), No. 258
  • Greenville (Dallas-Fort Worth), No. 275
  • Cedar Park (Austin), No. 280
  • Waxahachie (Dallas-Fort Worth), No. 306
  • Huntsville, No. 308
  • Hurst (Dallas-Fort Worth), No. 312
  • Socorro (El Paso), No. 339
  • Sherman, No. 368
  • Seguin (San Antonio), No. 375

Baytown, Port Arthur, and Texas City tied for first place in the U.S. in terms of highest average revenue per business.

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This article originally ran on CultureMap.

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Texas universities develop innovative open-source platform for cell analysis

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What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.