Report: Houston earns top-10 rank among best U.S. cities for workers making $100K

the good life

Six-figure earners live well in Houston. Photo via Getty Images

In Houston, $100,000 per year goes much farther than many other Texas cities. A new study by personal finance website GOBankingRates.com ranked Houston No. 7 on its list of the best cities for six-figure earners in the U.S.

The annual net pay after taxes for a six-figure earner in Houston comes out to $78,089, according to the study. When factoring in major expenses like rent, groceries, healthcare, utilities, transportation costs, and miscellaneous expenses, that adds up to $43,105.46 per year, which leaves just under $35,000 leftover. Houston's continuing inflation troubles surely aren't helping, either.

Here's how GOBankingRates breaks down Houston's expenses:

Annual rent: $19,215.67
Annual groceries: $5,594.64
Annual healthcare: $5,563.35
Annual utilities: $4,389.79
Annual transportation costs: $7,364.29
Annual miscellaneous costs: $977.72

Houston appears one spot lower than its No. 6-rank in a similar 2023 study by SmartAsset. That study said Houstonians' six-figure salary was reduced to $74,515 after taxes, but was technically worth $81,350 when adjusted for the cost of living.

Houston wasn't the only Texas city to earn a spot in the top 10 where a six-figure salary goes the farthest. Higher up on the list is El Paso (No. 2) and San Antonio (No. 3).

After taxes and annual expenses, six-figure earners in El Paso have $37,685 left over, which is over $2,700 more than what a Houstonian would have with the same salary. In San Antonio, residents making $100,000 per year average about $41,008 in annual expenses, which leaves $37,081 in their pockets after paying all the bills.

For the second year in a row, the U.S. city where a $100,000 salary goes the furthest is Memphis, Tennessee. Memphis residents have nearly $40,000 leftover after taxes and annual expenses on a $100,000 salary, the study says. Like Texas, Tennessee also doesn't impose an income tax on its residents.

The top 10 U.S. cities where a $100,000 salary goes the farthest are:

No. 1 – Memphis, Tennessee
No. 2 – El Paso, Texas
No. 3 – San Antonio, Texas
No. 4 – Tulsa, Oklahoma
No. 5 – Oklahoma City, Oklahoma
No. 6 – Wichita, Kansas
No. 7 – Houston
No. 8 – Tucson, Arizona
No. 9 – Jacksonville, Florida
No. 10 – Indianapolis, Indiana

In the study's analysis of the top 10 most expensive cities for six-figure earners, New York City took the crown as the city where residents are left "in the red" by the end of the year. Following close behind is San Francisco, California (No. 2); San Jose, California (No. 3); San Diego, California (No. 4); Boston, Massachusetts (No. 5); Oakland, California (No. 6); Los Angeles, California (No. 7); Washington, D.C. (No. 8); Miami, Florida (No. 9); and Long Beach, California (No. 10).

The report analyzed the average expense costs in 50 of the most populous American cities, and subtracted those costs from each city's annual net annual pay after taxes on a $100,000 salary. Rankings were determined based on the amount of annual income leftover. Data was pulled from the U.S. Census American Community Survey, the Bureau of Labor Statistics Consumer Expenditure Survey, the Zillow Observed Rental Index, and more.The report and its methodology can be found on gobankingrates.com.

------

This article originally ran on CultureMap.

Ad Placement 300x100

Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

Trending News

Editor's note: The Houston innovation scene is buzzing with big news this month, from a new accelerator joining the fold at the Ion to pre-IPO funding and national expansion plans. Below are the five most-read InnovationMap stories from Feb. 1-15, 2026:

New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

View All Listings

INNOVATIONMAP EMAILS ARE AWESOME