Tilman Fertitta's new book, "Shut Up and Listen!" is on its way to being a bestseller. Photo by J. Thomas Ford

Tilman Fertitta can't lose. Sitting in his palatial office nestled in the towering Post Oak Hotel in Uptown, the sole owner of Fertitta Entertainment, the restaurant giant Landry's, the Golden Nugget Casinos and Hotels, and the NBA's Houston Rockets — not to mention the star of the TV reality show Billion Dollar Buyer — is taking a quick moment to bask in his success.

And why not? On top of being the world's richest restauranteur and Houston's most recognizable billionaire, Fertitta currently boasts a best seller with his new business book, Shut Up and Listen! As CultureMap reported, he just acquired Del Frisco's luxury steakhouse chain, adding to his impressive and extensive restaurant empire. And speaking of acquisitions: Soon, his Houston Rockets will unleash the powerhouse duo of James Harden and new teammate Russell Westbrook, who came to Houston in a massive trade with Oklahoma City.

Fertitta has just made the national media rounds promoting Shut Up and Listen! and looked quite comfortable doing so. "A lot of owners don't talk to the media and they don't know how to do it," he tells CultureMap, "but I've been doing it for 30 years and it just doesn't phase me."

Shut Up and Listen! is a Tilman tell-all. But rather than a life story, the book is a how-to for the business-minded. No-nonsense nuggets such as the "Tilmanisms" teach principles such as the 95/5 rule (focus on the 5 percent of the operation that isn't perfect and fix it) and offer hardcore reminders such as "when things are bad, eat the weak and grow your business." Doubters, take note: Shut Up has landed on the Publishers Weekly's and USA Today's Best Sellers lists.

CultureMap sat down with Fertitta during a rare break to talk books, business, and his beloved Bayou City.

CultureMap: You're a Texan titan of industry, a major local benefactor, you own one of the most buzzworthy teams in all of pro sports, and you're the star of your own reality TV show. Can we now say — in Houston — that you're way bigger than Mark Cuban?

Tilman Fertitta: [Laughs] Oh, I don't know about that. Mark is a special guy and we're lucky to have him in Texas.

CM: You've been actively involved with the Rockets and the University of Houston sports programs. Using your 95/5 rule, can you share any of the 5 percent of what you found wrong with the Rockets and UH?

TF: At UH, the 5 percent was we wanted to have good coaches and we wanted to improve our facilities. That's the 5 percent we realized that if we wanted to compete at the highest level of basketball and football, that's what we'd have to do.

For the Rockets, we're gonna make sure we can put the basketball team we can on the court with the best coaches every single year. I'm not a sit-on-my-hands guy — it's let's keep getting better.

CM: Why is giving back to your hometown important to you?

TF: This is where I grew up and Houston's been very good to me. I've been around a long time and I've watched people come and go in the '80s, the '90s, the 2000s, and the 2010s. It's fun to have lasted this long and been a player through so many decades.

CM: There's an old adage that says, 'Do one thing and do it well.' But you're doing a lot of things well. When do you know, as a business owner, to diversify?

TF: Systems and operations are very important. Everybody wants to do more deals. If you understand the Big Box Theory, you make more out of a bigger box. In the beginning, I knew I always wanted to be successful. Today, I know what I know and I know — and what I don't know.

CM: Are there some industries outside your wheelhouse that are on your radar?

TF: I've never done egotistical businesses; I've always had to make the numbers work — because I never use anyone else's money. A lot of times, people who do egotistical businesses are using somebody else's money.

The only egotistical business I've done is probably the Post Oak Hotel here. But I did it because I got tired of people saying, 'Houston doesn't have an unbelievable hotel.' It's truly one of the finest hotels in the country.

CM: How important is it to find a mentor for success?

TF: I never had that one mentor. I looked at a lot of different people and said, 'Gosh, I like what they're doing.' I remember seeing George Mitchell and what he was doing in Galveston and The Woodlands. I would watch different people doing different things, but I never had that one mentor. I studied a lot of different people.
I'll never win an Emmy or a Grammy, but to me, if you can get on the Forbes 400, that's very special, because that's how you're measured.

CM: You've got this new book out that will hopefully inspire a generation of entrepreneurs. Are there any books that inspired you?

TF: Outliers inspired me. I do believe that different people are blessed with different abilities and you've got to find the ability that God gave you and seize on it.

I thought that I would always write a life story book, but Harper Collins approached me and said they wanted a business management book. I can't tell you how many times we sat around with my close group and edited this book at the end and went through it five times and read it. If we found a paragraph that was boring, we got rid of it or rewrote it.

CM: What about people who may never be an entrepreneur or owner — how can they become more successful with your book?

TF: Whether you're trying to go up the corporate ladder or you want to be an entrepreneur, it just tells you that you can separate yourself from anybody else. And it's easy to separate yourself from anybody else — I was never the smartest guy in the room or the best student. But the people who want to be successful are successful.

CM: There's a Tilmanism that teaches hiring people who are stronger than you. What are some key traits of a real leader?

TF: Anybody is a good leader in great times. First off, it's somebody who everybody in the room respects. And it somebody who knows what they know and what they don't know. Work is battle and being successful is a battle, and everybody wants to go into battle with a strong leader.

I can tell you this: You could talk to everybody who works for me and they'd tell you, 'He's a really hard person to work for, but I wouldn't want to work for anybody else.'

CM: With your travel schedule and empire, do you ever feel that you have more in common with a president of a country than a CEO?

TF: You know, it's funny, I told [Bill] Clinton once, 'I'm gonna still have these jets and helicopters when you're trying to hitch a ride.' I'm a very political person — on both sides — because I'm in business and I never know who's gonna be in power.

I would have no fear of being president tomorrow because it's about making hard decisions. I think a lot of presidents have never been in business and they don't even know how to make decisions. I make a tough decision every single day.

But, you know, I'm probably too honest to be a politician — I like to tell the truth. And I don't want to be beholden to anybody.

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This article originally ran on CultureMap.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”