Hannah Le founded RE.STATEMENT to provide a much-needed platform for sustainable fashion finds. Photo courtesy of RE.STATEMENT

When shopping online one day, Hannah Le saw a need for a platform that allowed transactions between upcycling fashion designers and shoppers looking for unique, sustainable pieces.

Le created RE.STATEMENT, an online shopping marketplace for upcycled clothing. Before RE.STATEMENT, designers were limited to Etsy, which is focused on handmade pieces, or Poshmark and Depop, which are dedicated to thrift finds. Upcycle fashion designers didn't have their own, unique platform to sell on — and, likewise, shoppers were scattered across sites too.

"These marketplaces are really good for what they do," Le says on this week's episode of the Houston Innovators Podcast, "but, whenever I think of someone looking for something unique and sustainable, it's hard for me to imagine finding that on these marketplaces."

The platform soft launched in December with 25 upcycling designers and over 1,200 buyers that had been on the company's waitlist for almost nine months. Now that the site is live, Le hopes to give both buyers and sellers quick access to transactions.

"Most designers give up if they haven't sold an item within three months," Le explains. "That's something RE.STATEMENT has dedicated its business model to — making sure that items sell faster and at a higher value than any other marketplace."

Le says that she started with buyers to see what exactly they were looking for, then she searched and found the designers looking to sell their pieces, and the current platform is dynamic and flexible to the needs of users within her community.

"Even today, it changes every single day depending on how users are interacting with the website and what sellers are saying that they need — really communicating with buyers and sellers is how the marketplace is evolving," she says.

RE.STATEMENT's ability to quickly evolve has been due to its early stage, Le explains on the show. She's not yet taken on institutional funding or hired anyone else other than tech support. She says this allows her to quickly make changes or try out new things for users.

"For me, there are still so many things I want to prove to myself before I bring others involved," she says. "To start, it's coming up with new opportunities for buyers to interact with the website so that we can keep learning from them."

Le has already proven some success to herself. Last year, she took home one of three prizes offered at the city's Liftoff Houston competition. The contest, which gives Houston entrepreneurs pitch practice and mentorship, awarded RE.STATEMENT $10,000 for winning in the product category.

"I wanted to see how far I could go," Le says of the competition where she got to introduce her business to Mayor Sylvester Turner and a whole new audience of people. "I had pitched before, but this was the first time that I was onstage and I just felt like I belonged there."

Le shares more about her vision for RE.STATEMENT and the integral role Houston plays in her success on the show.


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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Luxury transportation startup connects Houston with Austin and San Antonio

On The Road Again

Houston business and leisure travelers have a luxe new way to hop between Texas cities. Transportation startup Shutto has launched luxury van service connecting San Antonio, Austin, and Houston, offering travelers a comfortable alternative to flying or long-haul rideshare.

Bookings are now available Monday through Saturday with departure times in the morning and evening. One-way fares range from $47-$87, putting Shutto in a similar lane to Dallas-based Vonlane, which also offers routes from Houston to Austin and San Antonio.

Shutto enters the market at a time when highway congestion is a hotter topic than ever. With high-speed rail still years in the future, its model aims to provide fast, predictable service at commuter prices.

The startup touts an on-time departure guarantee and a relaxed, intimate ride. Only 12 passengers fit inside each Mercedes Sprinter van, equipped with Wi-Fi and leather seating. And each route includes a pit stop at roadside favorite Buc-ee's.

In announcing the launch, founder and CEO Alberto Salcedo called the company a new category in Texas mobility.

“We are bringing true disruptive mobility to Texas: faster and more convenient than flying (no security lines, no delays), more comfortable and exclusive than the bus or train, and up to 70 percent cheaper than private transfers or Uber Black,” Salcedo said in a release.

“Whether you’re commuting for business, visiting family, exploring Texas wineries, or doing a taco tour in San Antonio, Shutto makes traveling between these cities as easy and affordable as riding inside the city."

Beyond the scheduled routes, Shutto offers private, customizable trips anywhere in the country, a service it expects will appeal to corporate retreat planners, party planners, and tourists alike.

In Houston, the service picks up and drops off near the Galleria at the Foam Coffee & Kitchen parking lot, 5819 Richmond Ave.. In San Antonio, it is located at La Panadería Bakery’s parking lot at 8305 Broadway. In Austin, the location is the Pershing East Café parking lot at 2501 E. Fifth St.

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This article originally appeared on CultureMap.com.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”