Most leaders are so preoccupied with the health/well-being and engagement of their teams, they forget the steps necessary to take care of themselves. Photo via Pexels

Age-old advice for stressed caregivers typically shared by concerned friends and relatives is ‘take care of yourself first or you won’t have anything left for others.’ With or without the advice, many caregivers continue to selflessly do for others at the expense of their own health and well-being because it is in their DNA.

The workplace is no exception, especially for workers in leadership roles who have supported the emotional and physical needs of their staff nonstop for two years. Many leaders, from CEOs to frontline managers, have not only dealt with their own issues as a result of the pandemic, but also those of their teams, leaving them exhausted and suffering from compassion fatigue because they failed to follow their own advice.

Below are four ways leaders can manage compassion fatigue.

Lead by example

Leaders have spent countless time promoting company policies, programs and benefits that help employees deal with increased levels of stress in their professional and personal lives, which can have an impact on mental health and well-being. One of the first things leaders should do is set an example by utilizing the programs themselves to address compassion fatigue. Practicing what they preach not only supports the mental well-being of leaders, but it also demonstrates a culture that cares about mental health issues. Taking the initiative can encourage peers and others to take advantage of a company’s employee-support mechanisms.

Take time off

There are numerous reasons why many leaders are hesitant about taking time off, but the most common reasons are fear of being viewed as dispensable or worry that work will not get completed. It is not unusual for leaders to carry over weeks of PTO, or even lose it completely rather than use it. Disconnecting from work by taking time off is critical for renewal and emotional health that leads to rejuvenated leaders who are highly engaged and more motivated to lead their teams. While taking time off benefits leaders, it also builds confidence in staff because they recognize the trust that has been placed in them while the boss is gone.

Reach out to HR

Based on the widespread occurrence of compassion fatigue, chances are other leaders are experiencing the same feelings. Reaching out to HR can help get the ball rolling for additional programs designed to support leaders. For example, hosting lunch-and-learn sessions with medical professionals for advice, offering training sessions that cover relaxation methods, and creating a buddy system that pairs leaders for increased connections and mutual support. When leaders throughout the company realize they are not alone, they will feel more comfortable seeking help and participating in company-sponsored programs.

Develop a peer-to-peer accountability system

For higher-level executives who report directly to busy CEOs or a board of directors, there are fewer levels of oversight to address compassion fatigue. In fact, these may be the very individuals in most need of support. Executive teams should develop peer-to-peer accountability systems to support each other via biweekly mental health check-up chats, periodic PTO usage updates, quarterly retreats with dedicated downtime to relax, and weekly walking meetings. When executive teams create accountability systems, it helps to support mental health and well-being, build greater trust, and nurture stronger relationships that position leaders to better serve the organization.

It is no surprise that most leaders are so preoccupied with the health/well-being and engagement of their teams, they forget the steps necessary to take care of themselves. Leaders who embrace a popular philosophy – as go the leaders, so goes the culture and the company – should feel compelled to combat compassion fatigue by leading by example, taking time off, reaching out to HR and developing peer-to-peer accountability systems, putting their best selves forward to serve the needs of their teams and organization.

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Sherry Waters is vice president of field operations for Houston-based Insperity, a leading provider of human resources and business performance solutions.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”