Tech entrepreneur and Houston native shares why flexibility is the future of work

distributed work

Houston-born Matt Mullenweg joined the Greater Houston Partnership for a fireside chat on his tech company Automattic's success of distributed work. Photo via ma.tt

The pandemic and the measures companies have taken to prevent the spread of COVID-19 have opened employers eyes to non-traditional ways of working. An increased percentage of the workforce pivoted to remote working this year — in some cases, this was the first time employees were allowed to work from home.

But not having a traditional office setup is far from new to Houston native Matt Mullenweg, founder of WordPress. He started his company with remote team members basically from day one. In a virtual fireside chat with Scott McClelland, president of H-E-B Food & Drug, for Greater Houston Partnership's Houston NEXT: An ERG Summit last month, Mullenweg describes why he feels confident that a remote — or distributed, has he defines it — workforce is the future.

"Words are really important, and when I hear the word 'remote,' I think there's a central office and then there's someone who's not part of it," Mullenweg says during the chat. "So, we were trying to think of something that captured the fact that we were close to each other in our work — we're just not physically in the same place most of the time. 'Distributed' is what we came up with."

For Mullenweg, this way of running his business was advantageous for the company at its founding in 2000. Since those early days, Automattic, WordPress's parent company, has raised around $700 million in venture funding and made around 20 acquisitions. This success, Mullenweg says, is in part due to distributed work.

"All of this is designed to create a really robust network so that the work can continue regardless of location or anything," Mullenweg says on his workforce structure. "This especially during the early days, allowed us to work two or three times faster than our competitors because when they were doing five days of work a week, we were doing 15 days of work a week."

Mullenweg's plan for distributed work has been the subject a series of blogs, a podcast, and even a TED Talk. As passionate as he is that it is the future of the workforce, he realizes there's a process to getting there, and it's going to take time. He explains a five-tiered process that focuses on strategic culture changes and tech optimization.

"I think you need to have a culture and a way of working that allows people who aren't physical co-present with their colleagues to be productive," Mullenweg says. "The truth is not every company is there yet."

While Mullenweg always believed the rise of distributed work would reach milestones throughout his lifetime, the pandemic might be accelerating crucial steps toward the growth of this type of workforce. Especially since, as Mullenweg explains, this isn't the last major event that's going to occur and prevent in-person work.

"We're all hoping COVID to be gone as soon as possible, but this isn't the last thing like this. I'm sure there are going to be other issues that require us to be more decentralized in the future," Mullenweg says. "If you can get good at that as an organization, you'll be primed to succeed in the coming decades as a business."

Ultimately, distributed work has a lot of potential in the modern workforce, and the structure can do wonders for business advancement as well as employee moral.

"One thing we've found is that when people are really happy and fulfilled, they bring their best selves to work — they're more creative and have more energy," Mullenweg says.

Houston NEXT: An ERG Summit - Fireside Chat with Matt Mullenwegwww.youtube.com

Mayor Sylvester Turner talked parks, innovation, firefighter salaries, and more at the Greater Houston Partnership's State of the City. Natalie Harms/InnovationMap

5 things Mayor Turner promised Houston in his State of the City Address

Looking forward

In the 2019 State of the City Address hosted by the Greater Houston Partnership on May 20, Mayor Sylvester Turner took the stage at the Marriott Marquis in front of over 1,500 Houstonians.

Some of the obvious topics were of course on the table — pension reform, hurricane recovery, job growth — but Mayor Turner surprised attendees with the announcement of a public-private parks program and again alluded to the re-envisioned of Astroworld.

Here's what all the mayor promised in his address.

Public-private partnerships for Houston parks

Houston's major parks have undergone major transformations lately backed by private investments — Buffalo Bayou Park, Memorial Park Conservancy, and Bayou Greenways 2020, to name a few — but the city would like to shift focus to smaller, neighborhood parks across the city. To do this, Mayor Turner called for 50 companies to sponsor 50 parks.

"Today, I am asking the Greater Houston Partnership, the Houston Parks Board, and the Parks Department, to help me bring together 50 companies to form a citywide coalition for our neighborhood parks — primarily in underserved communities," Mayor Turner says.

Scott McClelland, president of HEB Food and Drug and board chair of the GHP, offered up HEB as a corporate partner for the program on the spot, despite the formal details of the program not yet being disclosed. Mayor Turner did specify that the park sponsorship would be a commitment over a few years.

"The 50 for 50 effort will touch every district in the city. All Houstonians should have easy access to welcoming, well-maintained, safe, and fun parks," he says.

A developed innovation corridor and a resurgence of AstroWorld

In both in his introductory address and fireside chat with McClelland, Mayor Turner talked about the emergence of Houston's innovation ecosystem. He cites the 140 percent increase in technology jobs as well as the 3,000 reported startups that call Houston their home. He mentions that Silicon Valley-based accelerator program Plug and Play is preparing to enter the market and another 25 million investment from the Houston Exponential fund of funds is expected.

"We're not walking; we're sprinting," Mayor Turner says. "There is no better place for an [innovation] ecosystem to take place than Houston."

Mayor Turner also credited Rice University's The Ion project as a major source of growth for the city's innovation ecosystem.

"We are building an innovation hub and corridor — in collaboration with academia, thank you, Rice, for loaning us the Sears building on South Main, and the energy and tech companies."

When discussing the innovation district, the mayor also gave a shout out to Travis Scott for being the "instigator" of a new AstroWorld-like theme park the city has in the works, but no details were disclosed in the address.

Rethinking Houston's transportation system

As Houston's population continues to grow, Houstonians spend more and more time in their cars fighting traffic. The mayor called for action to reimagine Houston's transportation.

"Our city has changed, the region is changing, and our transportation, transit, and mobility must change," he says. "People want options, and we must give them options."

Mayor Turner alluded to the Metro Next plan that will be on the ballot this November. While he didn't go into much detail, he encouraged support for the plan.

A raise for the Houston Fire Department

McClelland started the fireside chat with a question about the state of things after Proposition B's repeal following being deemed unconstitutional. The proposition, which originally passed last fall, would have matched Houston firefighters' salaries with police officers.

The mayor says that with the repeal, no layoffs or job cuts will be made within the Houston Fire Department. He recognizes that firefighters are in need of a raise, but it must be one the city can afford.

"Our firefighters are deserving of a pay raise," Mayor Turner says. "What I've put forth is 9.5 percent over three years, but look, my door is open."

The best is yet to come

Mayor Turner wrapped up his address on a positive note, saying that the city's growth will continue.

"The state of our city is strong, resilient, and sustainable," he says. "The best for us as a city has yet to come."

All of these initiatives on the mayor's agenda are working for toward uniting and enhancing Houston.

"We are building one complete city," he says. "And we work together, we win."

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

5 must-read innovation headlines: Pharma giant considers Houston hub + more

Trending news

Editor's note: With May coming to a close, it's time to look back at the biggest innovation headlines for the second half of the month. Major moves were made in May, with NuScale Power entering the market, Persona AI inking a deal with Under Armour, and a pharma giant considering Houston for its next manufacturing hub. Here are the most-read InnovationMap stories published May 15-29, 2026:

1. Pharma giant considers Houston for $1 billion manufacturing campus

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub. According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

2. Modular nuclear reactor co. NuScale Power moves into Houston market

The nuclear energy renaissance continues in Texas with an announcement by NuScale Power. The Oregon-based provider of proprietary and innovative advanced small modular reactor (SMR) nuclear technology announced in April it would be opening office space in Houston’s CityCentre.

3. Persona AI teams with Under Armour to protect next-gen robots

Houston-based Persona AI has cemented a partnership with sportswear manufacturer Under Armour to provide materials to protect future robots operating in dangerous conditions. Through the partnership, Persona AI and Under Armour will launch a research initiative to explore whether advanced performance textiles can improve the durability and resilience of humanoid robots operating in harsh industrial environments.

4. Houston quantum energy chip startup emerges from stealth with $12M round

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip. The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target.

5. Global summit spotlights Houston's growing role in brain health, innovation

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. The summit, held June 9-10 at the Texas Medical Center's Helix Park, will bring together more than 500 executives, researchers, policymakers and innovators from around the world to discuss the global brain economy.

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