This week's roundup of Houston innovators includes Michael Torres of CrossBridge Bio, Aileen Allen of Mercury, and Ryan Reisner of SeekerPitch. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes three innovators across therapeutics, venture capital, and HR software.

Michael Torres, CEO of CrossBridge Bio

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and CE-Ventures. Photo via crossbridgebio.com

A Houston biotech company based off research out of UTHealth Houston has raised seed funding to continue developing its cancer-fighting therapeutic.

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and Crescent Enterprises' VC arm, CE-Ventures. The round also included participation from Portal Innovations, Alexandria Venture Investments, Linden Lake Labs, and several pre-seed investors.

“We are thrilled to have the support of such experienced investors who share our vision of bringing transformative cancer therapies to patients in need,” Michael Torres, CEO of CrossBridge Bio, says in a news release. Torres served as an entrepreneur in residence of ACT. Continue reading.

Aileen Allen, venture partner at Mercury

Aileen Allen joined Mercury as venture partner and is on the board of the Houston Angel Network. Photo courtesy of Mercury

When Aileen Allen was contemplating a big career move — swapping sides of the table from tech company to venture investor — she was motivated by driving gender and experience diversity amongst decision makers.

"I've worked for VC-backed companies for most of my career and had the opportunity as an executive to be in the boardroom during that time," she says on the Houston Innovators Podcast. "One of my takeaways was that very few of my board members looked like me. I had one or two women on any of my boards at a time in totality, and very few of my board members had been operators."

"I'd really like to change that, and I'd like there to be better representation and diversification in the boardroom," she adds. Continue reading.

Ryan Reisner, president and founder of SeekerPitch

Ryan Reisner is the\u00a0president and founder of SeekerPitch and The Reisner Group. Photo via LinkedIn

Confident job seekers have mostly been of the mindset that if they can just get in front of an employer, they can sell themselves into an offer for the open position. The obstacle then, is getting through the screening process to get an actual interview.

Until recently, the price of admission for starting or progressing in a desired career was a resume and cover letter stellar enough to catch the eye of the human resources and recruiting team. Outside of being buried in the immense pile of resumes recruiters do not have the bandwidth to get to, standing out in the sea of candidates can be daunting.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed. So, what’s the solution?

It is a multi-layered problem, which requires a multi-layered solution, but one of the options gaining steam in the recruitment space is provided by SeekerPitch, a Houston-based HR technology platform utilizing generative AI to make hiring and interviewing more efficient.

“I've noticed that there's a ton of people that slip through the cracks,” says Ryan Reisner, president and founder of SeekerPitch and The Reisner Group. “And we spend all our time interviewing people to see if they have the soft skills. Resumes are hard skills. And now with AI, anybody can build the same exact resume. Everybody can say they have communication skills, leadership skills, and a lot of people say they have those." Continue reading.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed, but this Houston startup has a solution. Photo via Getty Images

Houston startup to transform hiring process with AI, video-optimized platform

cha-cha-changes

Confident job seekers have mostly been of the mindset that if they can just get in front of an employer, they can sell themselves into an offer for the open position. The obstacle then, is getting through the screening process to get an actual interview.

Until recently, the price of admission for starting or progressing in a desired career was a resume and cover letter stellar enough to catch the eye of the human resources and recruiting team. Outside of being buried in the immense pile of resumes recruiters do not have the bandwidth to get to, standing out in the sea of candidates can be daunting.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed. So, what’s the solution?

It is a multi-layered problem, which requires a multi-layered solution, but one of the options gaining steam in the recruitment space is provided by SeekerPitch, a Houston-based HR technology platform utilizing generative AI to make hiring and interviewing more efficient.

“I've noticed that there's a ton of people that slip through the cracks,” says Ryan Reisner, president and founder of SeekerPitch and The Reisner Group. “And we spend all our time interviewing people to see if they have the soft skills. Resumes are hard skills. And now with AI, anybody can build the same exact resume. Everybody can say they have communication skills, leadership skills, and a lot of people say they have those.

“But when it's all said and done, you interview those people to find out if they truly have them, and many of them don't have them. So, the resume is just a door opener. The door closer is the soft skills. So, with me being an underdog and growing up in underserved communities and just hoping to be found and applying to a bunch of places, I asked, what do I need to do to stand out from the crowd?”

Creating a solution

In addition to adding value during the actual interview, SeekerPitch solves the problem of feedback for applicants. Photo via SeekerPitch

That thought sparked the idea for the SeekerPitch platform and its signature feature that enables candidates to create video cover letters and skill-specific videos, allowing them to showcase their soft skills and personality.

In short, static candidate profiles come to life via SeekerPitch’s Pitch Sessions feature, which is purpose-built for job seekers to flesh out their full self and for employers to host multiple rounds of interviews with actionable insights from the platform’s generative AI to facilitate well-informed hiring decisions.

“Our product gives the employer a 30-second elevator pitch of an individual so they can interview people that are better fits for the jobs they are trying to fill,” says Reisner. “Unlike our competitors, we are normalizing ‘speed interviewing’ to maintain a more personal, holistic approach to the virtual interview.

“While the employer is interviewing the candidate in real time, the platform is transcribing the interview so the built-in AI model can give feedback such as culture fit, other mechanisms such as specific skills for a sales position and a total summary on that candidate’s ability to succeed in the role, which is enabling employers to make better hiring decisions and is vastly increasing the quality of the talent pool.”

In addition to adding value during the actual interview, SeekerPitch solves the problem of feedback for applicants.

“After the interview is completed, the employer has three choices: interested, still deciding and not interested,” adds Reisner. “And then if the employer is still deciding, it gives them a 72-hour countdown to make a decision and once that 72-hour window is over, that candidate is automatically rejected.

“What we have found is that job seekers, whether they're in the running or not, they just want to know, if they are moving forward or not. With our platform, they’re not stranded in feedback limbo for two plus weeks, so they love that part. They also like the holistic part where they're being judged off of who they are, their authenticity, and also their personality traits.”

Benefiting both sides of the equation

Ryan Reisner is the president and founder of SeekerPitch and The Reisner Group. Photo via LinkedIn

Another prime feature for employers is the video job description, which is expanding its reach with its intended audience: job seekers.

With everyone, including those in the candidate pool, now watching short-form videos on TikTok, Instagram, Snapchat, and YouTube as a lifestyle, employers can reach the next generation of the workforce using video job postings via the platform.

“Statistics show that 90 percent of job seekers don't even read job descriptions,” says Reisner. ”So, employers are automatically getting a poor candidate pool because it's easy to apply for job seekers and they just apply because it’s a numbers game. But what we have found is that the video job descriptions are an engaging medium that has vastly increased the quality candidate pool, as opposed to quantity.”

Another facet of SeekerPitch’s goal to streamline hiring is the automated scheduling process, whereby the platform uses chatbots to chat in real time with job seekers to get the best availability for interview time slots.

“We’ve also implemented an AI feature that helps the interviewer prepare for the interview based on the candidate’s profile, application and resume,” says Reisner. “It will provide questions to the interviewer that they might not have otherwise thought to ask to dive deeper into the candidate’s overall fit for the role. And based on the candidate's answers, more questions will populate tailored to that candidate.

“Then, after that interview is completed, and the employer is interested in moving the candidate forward in the interview process, it queues up the next interviewer in line to schedule that second or next round interview and so on. This automatically synchs with the employer’s applicant tracking system to get the employer all the way through the hiring process.”

Leveling the playing field

SeekerPitch won the third annual CodeLaunch Houston. Photo by Natalie Harms/InnovationMap

SeekerPitch’s goal is to also raise awareness about unconscious bias in the hiring process and point it out so that an employer can review any biases their team may have and improve upon them for their process moving forward.

Thanks to the platform’s unprecedented growth and innovation, SeekerPitch won over the crowd at the third annual CodeLaunch Houston event in March. The company has now moved on to CodeLaunch “World Championship” event in Dallas latter this month. The competition brings together the 8 best and the fastest-growing startups to compete for $50,000 in deployed investments and showcase their potential to venture capitalists and angel investors from across the country.

Whether or not SeekerPitch wins the competition, they’ll continue to make strides in the hiring vertical.

“Video is powerful,” says Reisner. “It can tell a story, so our platform makes it a better experience for the job seeker, giving them a competitive edge and helps them stand out from the crowd. We’ve only been in business for six months, but we will continue to disrupt the industry with this platform, especially with the proliferation of AI.”

SeekerPitch won the third annual CodeLaunch Houston. Photo by Natalie Harms/InnovationMap

2 Houston workforce solutions startups win at annual software pitch competition

winner, winner

The third annual CodeLaunch Houston event resulted in two winners — one chosen by the audience, the other by judges — both tackling separate issues in the future of work.

SeekerPitch, a next-generation hiring platform that provides artificial intelligence-enhanced and video technology tools to both job hunters and hiring teams, took the grant prize, which was voted on by the audience of the February 28 event. The team was supported by Honeycomb Software, which won last year's competition too with its startup partner, E360.

"In Gen Z right now, landing an interview is like winning the lottery," Ryan Reisner, president and founder of SeekerPitch, says in his pitch at the event. "And employers have their own set of problems — they're having a hard time connecting with the next generation."

iShiftX, supported by Houston-based Blue People, secured the judges' award with a tie-breaking vote. The company, founded by Landi Spearman, uses digital twin technology to provide 24/7 leadership coaching at a scalable level.

"Leaders have the biggest impact on our teams, our children, on the future, and on the next generation," Spearman says in her final appeal to judges and the audience. She called out the burnout and stress of leadership and coaching, and she pitched her tech enabled solution.

In addition to SeekerPitch and iShiftX, four other startups with their development support partners pitched, including:

The competition consisted of three rounds where two startups went head-to-head, and attendees were asked to vote for their favorite pitch. SeekerPitch, iShiftX, and Allonge Financial made it to the final round before the two winners were announced based on a final round of voting.
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CultureMap Emails are Awesome

Texas booms as No. 3 best state to start a business right now

Innovation Starts Here

High employment growth and advantageous entrepreneurship rates have led Texas into a triumphant No. 3 spot in WalletHub's ranking of "Best and Worst States to Start a Business" for 2026.

Texas bounced back into the No. 3 spot nationally for the first time since 2023. After dropping into 8th place in 2024, the state hustled into No. 4 last year.

Ever year, WalletHub compares all 50 states based on their business environment, costs, and access to financial resources to determine the best places for starting a business. The study analyzes 25 relevant metrics to determine the rankings, such as labor costs, office space affordability, financial accessibility, the number of startups per capita, and more.

When about half of all new businesses don't last more than five years, finding the right environment for a startup is vital for long-term success, the report says.

Here's how Texas ranked across the three main categories in the study:

  • No. 1 – Business environment
  • No. 11 – Access to resources
  • No. 34 – Business costs

The state boasts the 10th highest entrepreneurship rates nationwide, and it has the 11th-highest share of fast-growing firms. WalletHub also noted that more than half (53 percent) of all Texas businesses are located in "strong clusters," which suggests they are more likely to be successful long-term.

"Clusters are interconnected businesses that specialize in the same field, and 'strong clusters' are ones that are in the top 25 percent of all regions for their particular specialization," the report said. "If businesses fit into one of these clusters, they will have an easier time getting the materials they need, and can tap into an existing customer base. To some degree, it might mean more competition, though."

Texas business owners should also keep their eye on Houston, which was recently ranked the 7th best U.S. city for starting a new business, and it was dubbed one of the top-10 tech hubs in North America. Workers in Texas are the "third-most engaged" in the country, the study added, a promising attribute for employers searching for the right place to begin their next business venture.

"Business owners in Texas benefit from favorable conditions, as the state has the third-highest growth in working-age population and the third-highest employment growth in the country, too," the report said.

The top 10 best states for starting a business in 2026 are:

  • No. 1 – Florida
  • No. 2 – Utah
  • No. 3 – Texas
  • No. 4 – Oklahoma
  • No. 5 – Idaho
  • No. 6 – Mississippi
  • No. 7 – Georgia
  • No. 8 – Indiana
  • No. 9 – Nevada
  • No. 10 – California
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This article originally appeared on CultureMap.com.

Houston lab-test startup seeks $1M for nationwide expansion

Testing Access

Health care industry veteran Jim Gebhart knew there had to be a better way for patients to access lab services, especially those with high health insurance deductibles or no insurance at all.

“This challenge became deeply personal when a close family member developed a serious illness, and we struggled to secure prompt appointments,” Gebhart tells InnovationMap. “It’s incredibly frustrating when a loved one cannot receive timely care simply because of provider shortages or the limited capacity of traditional clinics.”

Driven by the desire to knock down lab-test barriers, Gebhart founded Houston-based TheLabCafe.com in 2024. The platform provides access to low-cost medical tests without requiring patients to carry health insurance. TheLabCafe serves patients in six states: Texas, Georgia, Louisiana, Nevada, New Mexico and Oklahoma. Gebhart, the startup’s CEO, says that by the end of March, LabCafe will be offering services in 20 more states and the District of Columbia.

Gebhart has spent more than 30 years in the lab industry. His career includes stints at Austin-based Clinical Pathology Laboratories, Ohio’s Cleveland Clinic Laboratories and Secaucus, New Jersey-based Quest Diagnostics.

“Since nearly 80 percent of disease diagnoses rely on laboratory testing, I decided to leverage my background to create a more accessible, self-directed process for individuals to order blood and urine tests on their own terms — when and where they need them,” says Gebhart.

So far, Gebhart is self-funding the startup. But he plans to seek $700,000 to $1 million in outside investments in late 2026 to support the nationwide expansion and the introduction of more services.

TheLabCafe contracts with labs for an array of tests, such as cholesterol, hepatitis, metabolic, testosterone, thyroid and sexually transmitted infection (STI) tests. A cholesterol test obtained through TheLabCafe might cost $29, compared with a typical cost of perhaps $39 to $59 without insurance.

A health care professional reviews every test, both when the test is ordered and when the results are delivered, often within 24 hours. After receiving test results, a patient can schedule a virtual visit with a health care professional to go over the findings and learn potential treatment options.

Gebhart says TheLabCafe particularly benefits uninsured patients, including those in Texas. Among the states, Texas has the highest rate of uninsured residents. U.S. Census Bureau data shows 21.6 percent of adults and 13.6 percent of children in Texas lacked health insurance in 2024.

“Uninsured patients often pay the highest prices in the health care system,” Gebhart explains. “We address this by offering straightforward pricing and convenient access to testing without requiring insurance.”

“Our rates are intentionally set to remain affordable, helping individuals take a proactive approach to their health,” he adds. “Regular testing enables people to identify potential health issues early and track their progress as they make lifestyle changes. Ultimately, you can’t measure improvement without data — and laboratory results provide that data.”

Houston geothermal startup secures $97M Series B for next-gen power

fresh funding

Houston-based geothermal energy startup Sage Geosystems has closed its Series B fundraising round and plans to use the money to launch its first commercial next-generation geothermal power generation facility.

Ormat Technologies and Carbon Direct Capital co-led the $97 million round, according to a press release from Sage. Existing investors Exa, Nabors, alfa8, Arch Meredith, Abilene Partners, Cubit Capital and Ignis H2 Energy also participated, as well as new investors SiteGround Capital and The UC Berkeley Foundation’s Climate Solutions Fund.

The new geothermal power generation facility will be located at one of Ormat Technologies' existing power plants. The Nevada-based company has geothermal power projects in the U.S. and numerous other countries around the world. The facility will use Sage’s proprietary pressure geothermal technology, which extracts geothermal heat energy from hot dry rock, an abundant geothermal resource.

“Pressure geothermal is designed to be commercial, scalable and deployable almost anywhere,” Cindy Taff, CEO of Sage Geosystems, said in the news release. “This Series B allows us to prove that at commercial scale, reflecting strong conviction from partners who understand both the urgency of energy demand and the criticality of firm power.”

Sage reports that partnering with the Ormat facility will allow it to market and scale up its pressure geothermal technology at a faster rate.

“This investment builds on the strong foundation we’ve established through our commercial agreement and reinforces Ormat’s commitment to accelerating geothermal development,” Doron Blachar, CEO of Ormat Technologies, added in the release. “Sage’s technical expertise and innovative approach are well aligned with Ormat’s strategy to move faster from concept to commercialization. We’re pleased to take this natural next step in a partnership we believe strongly in.”

In 2024, Sage agreed to deliver up to 150 megawatts of new geothermal baseload power to Meta, the parent company of Facebook. At the time, the companies reported that the project's first phase would aim to be operating in 2027.

The company also raised a $17 million Series A, led by Chesapeake Energy Corp., in 2024.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.