This week's roundup of Houston innovators includes Michael Torres of CrossBridge Bio, Aileen Allen of Mercury, and Ryan Reisner of SeekerPitch. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes three innovators across therapeutics, venture capital, and HR software.

Michael Torres, CEO of CrossBridge Bio

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and CE-Ventures. Photo via crossbridgebio.com

A Houston biotech company based off research out of UTHealth Houston has raised seed funding to continue developing its cancer-fighting therapeutic.

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and Crescent Enterprises' VC arm, CE-Ventures. The round also included participation from Portal Innovations, Alexandria Venture Investments, Linden Lake Labs, and several pre-seed investors.

“We are thrilled to have the support of such experienced investors who share our vision of bringing transformative cancer therapies to patients in need,” Michael Torres, CEO of CrossBridge Bio, says in a news release. Torres served as an entrepreneur in residence of ACT. Continue reading.

Aileen Allen, venture partner at Mercury

Aileen Allen joined Mercury as venture partner and is on the board of the Houston Angel Network. Photo courtesy of Mercury

When Aileen Allen was contemplating a big career move — swapping sides of the table from tech company to venture investor — she was motivated by driving gender and experience diversity amongst decision makers.

"I've worked for VC-backed companies for most of my career and had the opportunity as an executive to be in the boardroom during that time," she says on the Houston Innovators Podcast. "One of my takeaways was that very few of my board members looked like me. I had one or two women on any of my boards at a time in totality, and very few of my board members had been operators."

"I'd really like to change that, and I'd like there to be better representation and diversification in the boardroom," she adds. Continue reading.

Ryan Reisner, president and founder of SeekerPitch

Ryan Reisner is the\u00a0president and founder of SeekerPitch and The Reisner Group. Photo via LinkedIn

Confident job seekers have mostly been of the mindset that if they can just get in front of an employer, they can sell themselves into an offer for the open position. The obstacle then, is getting through the screening process to get an actual interview.

Until recently, the price of admission for starting or progressing in a desired career was a resume and cover letter stellar enough to catch the eye of the human resources and recruiting team. Outside of being buried in the immense pile of resumes recruiters do not have the bandwidth to get to, standing out in the sea of candidates can be daunting.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed. So, what’s the solution?

It is a multi-layered problem, which requires a multi-layered solution, but one of the options gaining steam in the recruitment space is provided by SeekerPitch, a Houston-based HR technology platform utilizing generative AI to make hiring and interviewing more efficient.

“I've noticed that there's a ton of people that slip through the cracks,” says Ryan Reisner, president and founder of SeekerPitch and The Reisner Group. “And we spend all our time interviewing people to see if they have the soft skills. Resumes are hard skills. And now with AI, anybody can build the same exact resume. Everybody can say they have communication skills, leadership skills, and a lot of people say they have those." Continue reading.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed, but this Houston startup has a solution. Photo via Getty Images

Houston startup to transform hiring process with AI, video-optimized platform

cha-cha-changes

Confident job seekers have mostly been of the mindset that if they can just get in front of an employer, they can sell themselves into an offer for the open position. The obstacle then, is getting through the screening process to get an actual interview.

Until recently, the price of admission for starting or progressing in a desired career was a resume and cover letter stellar enough to catch the eye of the human resources and recruiting team. Outside of being buried in the immense pile of resumes recruiters do not have the bandwidth to get to, standing out in the sea of candidates can be daunting.

Resumes do not tell the full story as it is and it’s almost impossible for applicants to put their potential, soft skills and work personality into a document to be reviewed. So, what’s the solution?

It is a multi-layered problem, which requires a multi-layered solution, but one of the options gaining steam in the recruitment space is provided by SeekerPitch, a Houston-based HR technology platform utilizing generative AI to make hiring and interviewing more efficient.

“I've noticed that there's a ton of people that slip through the cracks,” says Ryan Reisner, president and founder of SeekerPitch and The Reisner Group. “And we spend all our time interviewing people to see if they have the soft skills. Resumes are hard skills. And now with AI, anybody can build the same exact resume. Everybody can say they have communication skills, leadership skills, and a lot of people say they have those.

“But when it's all said and done, you interview those people to find out if they truly have them, and many of them don't have them. So, the resume is just a door opener. The door closer is the soft skills. So, with me being an underdog and growing up in underserved communities and just hoping to be found and applying to a bunch of places, I asked, what do I need to do to stand out from the crowd?”

Creating a solution

In addition to adding value during the actual interview, SeekerPitch solves the problem of feedback for applicants. Photo via SeekerPitch

That thought sparked the idea for the SeekerPitch platform and its signature feature that enables candidates to create video cover letters and skill-specific videos, allowing them to showcase their soft skills and personality.

In short, static candidate profiles come to life via SeekerPitch’s Pitch Sessions feature, which is purpose-built for job seekers to flesh out their full self and for employers to host multiple rounds of interviews with actionable insights from the platform’s generative AI to facilitate well-informed hiring decisions.

“Our product gives the employer a 30-second elevator pitch of an individual so they can interview people that are better fits for the jobs they are trying to fill,” says Reisner. “Unlike our competitors, we are normalizing ‘speed interviewing’ to maintain a more personal, holistic approach to the virtual interview.

“While the employer is interviewing the candidate in real time, the platform is transcribing the interview so the built-in AI model can give feedback such as culture fit, other mechanisms such as specific skills for a sales position and a total summary on that candidate’s ability to succeed in the role, which is enabling employers to make better hiring decisions and is vastly increasing the quality of the talent pool.”

In addition to adding value during the actual interview, SeekerPitch solves the problem of feedback for applicants.

“After the interview is completed, the employer has three choices: interested, still deciding and not interested,” adds Reisner. “And then if the employer is still deciding, it gives them a 72-hour countdown to make a decision and once that 72-hour window is over, that candidate is automatically rejected.

“What we have found is that job seekers, whether they're in the running or not, they just want to know, if they are moving forward or not. With our platform, they’re not stranded in feedback limbo for two plus weeks, so they love that part. They also like the holistic part where they're being judged off of who they are, their authenticity, and also their personality traits.”

Benefiting both sides of the equation

Ryan Reisner is the president and founder of SeekerPitch and The Reisner Group. Photo via LinkedIn

Another prime feature for employers is the video job description, which is expanding its reach with its intended audience: job seekers.

With everyone, including those in the candidate pool, now watching short-form videos on TikTok, Instagram, Snapchat, and YouTube as a lifestyle, employers can reach the next generation of the workforce using video job postings via the platform.

“Statistics show that 90 percent of job seekers don't even read job descriptions,” says Reisner. ”So, employers are automatically getting a poor candidate pool because it's easy to apply for job seekers and they just apply because it’s a numbers game. But what we have found is that the video job descriptions are an engaging medium that has vastly increased the quality candidate pool, as opposed to quantity.”

Another facet of SeekerPitch’s goal to streamline hiring is the automated scheduling process, whereby the platform uses chatbots to chat in real time with job seekers to get the best availability for interview time slots.

“We’ve also implemented an AI feature that helps the interviewer prepare for the interview based on the candidate’s profile, application and resume,” says Reisner. “It will provide questions to the interviewer that they might not have otherwise thought to ask to dive deeper into the candidate’s overall fit for the role. And based on the candidate's answers, more questions will populate tailored to that candidate.

“Then, after that interview is completed, and the employer is interested in moving the candidate forward in the interview process, it queues up the next interviewer in line to schedule that second or next round interview and so on. This automatically synchs with the employer’s applicant tracking system to get the employer all the way through the hiring process.”

Leveling the playing field

SeekerPitch won the third annual CodeLaunch Houston. Photo by Natalie Harms/InnovationMap

SeekerPitch’s goal is to also raise awareness about unconscious bias in the hiring process and point it out so that an employer can review any biases their team may have and improve upon them for their process moving forward.

Thanks to the platform’s unprecedented growth and innovation, SeekerPitch won over the crowd at the third annual CodeLaunch Houston event in March. The company has now moved on to CodeLaunch “World Championship” event in Dallas latter this month. The competition brings together the 8 best and the fastest-growing startups to compete for $50,000 in deployed investments and showcase their potential to venture capitalists and angel investors from across the country.

Whether or not SeekerPitch wins the competition, they’ll continue to make strides in the hiring vertical.

“Video is powerful,” says Reisner. “It can tell a story, so our platform makes it a better experience for the job seeker, giving them a competitive edge and helps them stand out from the crowd. We’ve only been in business for six months, but we will continue to disrupt the industry with this platform, especially with the proliferation of AI.”

SeekerPitch won the third annual CodeLaunch Houston. Photo by Natalie Harms/InnovationMap

2 Houston workforce solutions startups win at annual software pitch competition

winner, winner

The third annual CodeLaunch Houston event resulted in two winners — one chosen by the audience, the other by judges — both tackling separate issues in the future of work.

SeekerPitch, a next-generation hiring platform that provides artificial intelligence-enhanced and video technology tools to both job hunters and hiring teams, took the grant prize, which was voted on by the audience of the February 28 event. The team was supported by Honeycomb Software, which won last year's competition too with its startup partner, E360.

"In Gen Z right now, landing an interview is like winning the lottery," Ryan Reisner, president and founder of SeekerPitch, says in his pitch at the event. "And employers have their own set of problems — they're having a hard time connecting with the next generation."

iShiftX, supported by Houston-based Blue People, secured the judges' award with a tie-breaking vote. The company, founded by Landi Spearman, uses digital twin technology to provide 24/7 leadership coaching at a scalable level.

"Leaders have the biggest impact on our teams, our children, on the future, and on the next generation," Spearman says in her final appeal to judges and the audience. She called out the burnout and stress of leadership and coaching, and she pitched her tech enabled solution.

In addition to SeekerPitch and iShiftX, four other startups with their development support partners pitched, including:

The competition consisted of three rounds where two startups went head-to-head, and attendees were asked to vote for their favorite pitch. SeekerPitch, iShiftX, and Allonge Financial made it to the final round before the two winners were announced based on a final round of voting.
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CultureMap Emails are Awesome

Houston cleantech, space startups named to World Economic Forum cohort

top honor

Two Houston-based startups have been selected to join the World Economic Forum's Technology Pioneers community.

The two-year program aims to help mission-driven, early-stage start-ups scale their innovations through multi-stakeholder initiatives, co-creating partnerships and other gatherings for community members. One-hundred startups are selected each year from around the globe, this year hailing from 23 countries and working in AI, energy, space, biotech markets and more.

Cleantech startup Vaulted Deep was one of 11 energy and climate companies to be named to the cohort. Julia Reichelstein and Omar Abou-Sayed founded the company in 2023. Its technology injects excess organic waste underground to remove carbon dioxide from the atmosphere.

Last year, Vaulted Deep inked a 12-year deal with Microsoft to remove up to 4.9 million metric tons of carbon dioxide from the environment.

The startup has earned several accolades in recent years, including a No. 3 spot on Fast Company’s list of the World’s Most Innovative Companies of 2026. It was also recently named to market intelligence and advisory firm Cleantech Group's annual Global Cleantech 100 list for a second year in a row.

"Waste management is one of the world's great invisible infrastructure systems ... The need for new infrastructure is growing as disposal challenges become more complex and regulations evolve. Vaulted is building the first new disposal pathway for organic waste in decades by putting it deep underground, permanently," the company shared in a LinkedIn post. "This year, we're joining the World Economic Forum's 2026 Tech Pioneers alongside innovators working on the many interconnected challenges shaping our future."

Houston-based Venus Aerospace was also selected to join the cohort, along with six other spacetech companies. The company was founded in 2020 by Sassie and Andrew Duggleby.

The startup specializes in next-generation rocket engine propulsion as a cleaner alternative to traditional combustion engines. The company's rotating detonation rocket engine (RDRE) burns fuel more efficiently and completed a successful high-thrust test flight last year. Venus says it’s the only company in the world that makes a flight-proven, high-thrust RDRE with a “clear path to scaled production.”

"Frontier technologies matter most when they expand what people, industries, and nations can do," Sassie Duggleby, co-founder and CEO of Venus, said in a news release. "For Venus, RDRE does not just represent a more efficient engine. It is a foundation for faster movement, more capable space systems, and new forms of connectivity across the planet. Being named a Technology Pioneer validates the potential of this technology to help shape a future where distance is less limiting."

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston Methodist receives record $110M gift, names future tower

historic gift

Houston Methodist has received the largest gift in the health system's history to establish new funds for neurological, neuroscience, and women’s health research and treatment.

The $110 million gift comes from Houston-based The Brockman Medical Research Foundation, which supports education and research in the science, medicine and healthcare fields. In response, Houston Methodist announced that it will name its forthcoming 26-story hospital facility the Brockman Centennial Tower.

The tower’s entrance will be named the Anna Margaret Bellows Centennial Hall to honor Anna Margaret Bellows, a young camper who died during the Camp Mystic flooding last summer.

“This extraordinary gift accelerates discovery and transforms how care is delivered,” Dr. Marc Boom, president and CEO of Houston Methodist, said in a news release. “We are grateful to The Brockman Medical Research Foundation for its incredible generosity and vision that will help change the lives of generations of patients. Naming Centennial Tower in recognition of this gift reflects the scale of this commitment and its impact on the future of neuroscience, neurological care and women’s health.”

The gift will be divided into two parts:

  • $100 million will go toward creating an innovation fund within the Houston Methodist Academic Institute and the Houston Methodist Neurological Institute
  • $10 million will be devoted to Houston Methodist's Department of Obstetrics and Gynecology

“This tremendous gift will accelerate translational research that broadens our understanding of neurological and other diseases,” Dr. Jenny Chang, president and CEO of the Houston Methodist Academic Institute, added in the release. “It will allow us to leverage state-of-the-art platforms to detect, diagnose and deliver therapeutics, keeping patient care at the center of our mission.”

The Brockman Centennial Tower is expected to open next year in the Texas Medical Center. Spanning more than 1 million square feet, it will house 400 patient beds, an expanded emergency department, new operating rooms and a rooftop garden. It will be connected to Houston Methodist's flagship Paula and Joseph C. “Rusty” Walter III Tower, which opened in 2018. The Centennial Tower was estimated to cost $1.4 billion when announced in 2022.

In addition to the news of the Brockman gift, Houston Methodist also announced this month that it has launched the Houston Methodist Center for Cell and Gene Therapy and tapped an internationally recognized scientist as its leader.

The new center is focused on discovering and developing innovative and cost-effective therapies for a variety of congenital and acquired diseases, including cancer, HIV and cardiovascular disease.

Dr. Malcolm Brenner has been named as the center's inaugural leader and will assume the role starting in October. He will work alongside scientists and support staff from Baylor College of Medicine and Texas Children's Hospital.

Brenner is a professor of pediatrics, medicine, molecular and human genetics and translational biology at Baylor College of Medicine. He is known for making early advances in using bone marrow transplantation as a form of cell therapy and in engineered immune-cell treatments for cancer and infections, according to a release from Houston Methodist.

“Malcolm Brenner is a pioneer in the field of cell and gene therapy and is uniquely qualified to lead Houston Methodist’s research efforts in this field,” Chang added. “His vision and leadership will play a pivotal role in advancing our work in this space.”