The future of resilience innovation will require all hands on deck. Photo via Getty Images

As Houstonians know more than most, a natural disaster can set a thriving city back millions. And, as it seems, these natural disasters aren't going anywhere. The question innovators, governments, insurance companies, and affected citizens keep asking is "what can be done?"

"Over the past decade we've been in and out of several disasters in the billions of dollars of impact," says Richard Seline, managing partner at ResilientH2O Partners. "But it's not without response."

Governments are deploying billions into fixing infrastructure, and Seline gathered risk mitigation experts for a conversation and startup pitch session as a part of Houston Tech Rodeo to discuss the future of this field. The experts weighed in on how risk mitigation and disaster prevention is going to need to be supported by both local and national governments.

Pamela Williams, executive director at BuildStrong Coalition, says she's been in the industry for decades now and has observed new financial support opportunities coming in at a federal level. These entities are looking for cost effective, risk reducing technologies. Innovators can think of these resources as seed funds — with a very high return on investment.

"Investments pre-disaster to draw down risk will save us … up to $11 for every $1 invested," she says on the panel. "Pre-disaster mitigation is where it's at."

And the solutions can't just come from one office within the national government — it needs to be a collaborative effort, she adds.

"We have got to provide flexibility, consistency — and truly be able to leverage all of these resources together so that we can do these transformational unthought of projects," Williams says.

Local governments are also tasked with increasing focus and funding on disaster prevention — maybe even more so than federal agencies, says Ron Prater, executive director at Big City Offices of Emergency Management.

"All disasters are local," he explains. "Locals have to be ready. ...Feds have money and resources but they aren't going to come in and save the day."

Governmental support is going to be needed to advance risk mitigation technology and innovation, but entrepreneurs might also have to seek aid elsewhere.

"While there are funds available for entrepreneurs and innovators, the fact is it will not always come from the government," Seline says. "There are billions of dollars of insurance, reinsurance, and non-traditional financing beginning to emerge — most of it centered around insuratech."

Williams says companies have a unique role to play in the continued conversation of driving these types of inventions.

"Our private sector partners have the ability to convene people," she says, "and bring perspectives to the table that have never before been there to come up with creative solutions."

Cultivating diverse thought leadership is crucial to the equation, says panel moderator Landi Spearman, generational and change management consultant at Organized Shift, who explains that Houston is an especially strategic place for this innovation to occur, since it's the most diverse big city in the country.

"When we think about resilience and people, we get to leverage our diversity of perspective. You get to bring yourself to the solution and you get to include others," she says.

There are a few types of exciting technologies emerging in resilience innovation — from finding ways to optimize and assist brokers and carriers as well as the equipment, technology, and data that's coming out of the public-private sector. One that interests Prater in particular is the opportunity to collect data.

"AI and machine learning are going to improve how (emergency managers) get situation awareness — how accurate it is and how timely it is," he says. "One of their main goals is to share as much information as possible."

The panel concluded with three startup pitches from NanoTech, a fireproofing and insulation product; IVPAir, a device that kills COVID-19 germs right from the air; and Climaguard, a weatherproofing invention to protect cars.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.