A local church is deploying handwashing stations across town. Photo by Nijalon Dunn

When the coronavirus forced the closure of restaurants, stores, and community centers, it disproportionally affected the health of a population of people: The homeless.

Homeless individuals are acutely vulnerable amid the public health and hygiene concerns due to the coronavirus pandemic, says Houstonian Nijalon Dunn. These communities of people have been left without immediate access to soap and clean water, especially with the closure of local businesses whose restrooms sometimes served as individuals' only sources of clean water.

"[Local businesses are] where people were able to use the restroom, wash their hands and have access to soap and water," Dunn says. "Take public restrooms away, now you have an increase in public urination and people using the restroom outside. Not only that, but people aren't washing their hands because of a lack of education and awareness about social distancing and hygiene practices."

Observing this effect of the virus, a group of Houstonians pulled together their skills and resources to provide handwashing stations across the city for Houston's homeless population.

Rise Houston Church, a local organization servicing inner-city Houston, is behind the initiative. Eager to help the community during the coronavirus pandemic, Rise Houston's pastor Stan DePue proposed the idea of building and distributing handwashing stations that would provide clean water and soap to homeless communities.

Dunn paired used his photography and filmmaking skills for a great cause when partnering with Rise Houston: Clean Hands. Dunn, a member of Rise Houston and founder of Black Visa Creative, a Houston company specializing in creative and commercial portraits that help small businesses tell their stories, knew that he could elevate DePue's project's reach and awareness through photojournalism.

"For us to have the impact and raise the support we needed, I knew that we needed to be documenting this [project]. So [Stan] and I partnered," Dunn says.

The idea evolved into an initiative with 10 sinks deployed across the city of Houston. According to Rise Houston's website, the sinks cost $300 to install. The church is looking for support in funding and maintaining the sinks — more information on giving back is available online.

DePue and his congregation are running the project's operation and physically constructing the sinks, and Dunn overseeing the project's documentation and awareness.

"We've been working with boots on the ground, creating partnerships so that we have strategic locations [for sinks] and know that they'll serve the best purpose in the areas where we place them," Dunn says.

After sink locations were identified across Houston, Rise Houston: Clean Hands volunteers delivered and set up the sinks on-site, each complete with a seven-gallon water tank, a water dispenser foot pump, soap and paper towel dispensers, trash bags, and signs that encourage the six-feet-apart social distancing rule.

"In order to stop the spread of coronavirus and flatten the curve, we needed to bring innovation to the way we serve our homeless brothers and sisters during this time," Dunn says.

A striking observation from Dunn's experience with this project, and the individuals he has worked and conversed with, has been how grateful people have been to learn about and be exposed to hygienic resources and practices, Dunn says.

"One of the greatest assets of the storyteller is knowing when to put the camera down. Some of the places we go to are some of the most vulnerable places in the city," Dunn says. "When we go into these homeless camps, I need to know when to put the camera down and live and exist with the person I talk to."

Through these interpersonal encounters, the teamwork of Rise Houston: Clean Hands volunteers and Dunn's innovative approach to communicating about this issue, the initiative has been able to sustain maintenance of the sinks and further spread hygienic awareness to Houstonians.

Letting hygiene sink in

Photo by Nijalon Dunn

Rise Houston: Clean Hands has deployed 10 outdoor sinks across Houston.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”