Introducing the Rice Nexus. Rendering courtesy of Rice University

Rice University is going beyond the hedges with its hub at the Ion, for which the school has just details and renderings.

For over a year, Rice has been planning its Rice Nexus, a collaborative hub for the university's innovation efforts located in the Ion District, Rice Management Company's 16-acre district in Midtown. Expected to open this fall, the new space will be located across 10,000 square feet on two floors of the Ion.

“We believe in the power of innovation to transform lives and shape the future,” Rice President Reginald DesRoches says in a news release. “With the launch of the Rice Nexus at the Ion, we are embarking on a journey to unleash the full potential of Houston’s innovation ecosystem, driving positive change and rapid economic growth.”

Rendering courtesy of Rice University

The Rice Nexus will provide the university's community with prototyping tools, access to venture capital opportunities, and entrepreneurial support.

“We are thrilled to introduce the Nexus so that our faculty and students can rapidly develop, derisk and deploy solutions into the world by harnessing the full resources and capabilities of the Ion District,” Paul Cherukuri, Rice’s chief innovation officer, adds. “Houston is a grand city of innovation, and the Nexus at the Ion further amplifies Rice as a global leader in inventing and commercializing world-changing technology at both speed and scale.”

Rice reports that three startups founded by faculty — Solidec, Coflux Purification, and DirectH2 — will be located in the facility.

“The critical support provided through the Nexus highlights Rice’s leadership in pioneering essential hard tech development in the middle of the world’s energy capital, revolutionizing the country’s next-generation clean energy and chemical manufacturing technologies while fostering the next generation of innovators in energy sustainability,” says DirectH2 Co-Founder Aditya Mohite, professor of chemical and biomolecular engineering, electrical and computer engineering and materials science and nanoengineering.

Rendering courtesy of Rice University

Rice University is in the process of restructuring operations at the Ion. Photo courtesy of the Ion

Houston innovation hub restructures, pulls in more Rice resources

cha-cha-changes

Rice University is leaning in on the Ion by restructuring the innovation hub's team and increasing the university's presence at the hub.

Paul Cherukuri, vice president for innovation, tells InnovationMap that the changes being made at the Ion — Rice's Midtown innovation hub — are a reflection of Rice President Reginald DesRoches's vision for the hub and for the university as a leader of innovation.

"We're embracing the community even further by what we've done with this restructuring," Cherukuri says. "The restructuring is really a result of Reggie's vision of us wanting to move forward with helping the community to grow innovation across Houston, throughout Texas, if not the world."

He adds that the university is "putting resources from Rice Alliance and amping up what's happening at the Ion."

Earlier this month, Rice announced that Brad Burke, executive director of the Rice Alliance for Technology and Entrepreneurship, has been named associate vice president for industry and new ventures reporting to Cherukuri's Office of Innovation.

Cherukuri confirms that the Rice Alliance will take over programming at the Ion, and that he too will have an increased presence at the hub. The restructuring includes elimination of positions at the Ion; however, Rice declined to comment on matters of personnel.

"We have members of the Ion staff who are going to be integrated to the Rice Alliance," Cherukuri says. "The direction of this is really so that we can no longer stay behind the hedges and do more for the Houston community."

Cherukuri says the university has already made a concerted effort on this, and soon will deliver on the Rice Nexus, a hub within the Ion for showcasing and connecting Rice innovation. Additionally, Rice announced last month that it's partnering with Woodside Energy, which committed $12.5 million over the next five years to create the Woodside Rice Decarbonization Accelerator.

Last year, Cherukuri joined the Houston Innovators Podcast to expound upon his vision for the Ion in his role as the inaugural vice president for innovation, which he was named to in 2022.


In his new role, Adrian Trömel will oversee the creation of the Rice Nexus, an innovation hub within the Ion that aims to bridge the gap between the university and Houston's innovation ecosystem. Photo courtesy of Rice

University names Houston founder to leadership role to oversee new innovation hub

next up for the rice nexus

Rice University’s Office of Innovation has named Houston materials scientist-turned-entrepreneur Adrian Trömel as its new assistant vice president for strategy and investments.

Trömel founded non-invasive neurostimulation medical device company CNX Medical at the Texas Medical Innovation Institute in 2019 and most recently served as chief growth officer for Hamilton Health Box, which brings an on-site care team to company offices.

In his new role, Trömel will oversee the creation of the Rice Nexus, an innovation hub within the Ion that aims to bridge the gap between the university and Houston's innovation ecosystem. He will also lead the creation of a translational research grant fund and a university-affiliated venture fund for Rice-affiliated entrepreneurs, according to the release.

“Adrian brings a broad, multidisciplinary background to the team at the Office of Innovation,” Paul Cherukuri, chief innovation officer at Rice, says in a statement. “As a materials scientist and entrepreneur, his experience can be brought to bear to help faculty and students spin out new technologies and start new ventures.”

Trömel holds a bachelor’s and master’s in materials sciences from the École polytechnique fédérale de Lausanne (EPFL) and the Netherlands and an MBA from Rice. He is also an angel investor and a lead lecturer for Rice's New Enterprise MBA ELab.

In addition to his professional work, he serves as the foreign trade advisor to the Ministry of Economy of Luxembourg.

Rice has been building up its Office of Innovation in the last few years. In August 2022, the university named Cherukuri as the inaugural vice president for innovation. According to Rice President Reginald DesRoches, the Office of Innovation and the Cherukuri's position were created to ensure Rice is a leader within Houston and the global innovation ecosystem.

This past March, Cherukuri announced plans to develop the Rice Nexus.

"We've got so much technology in our labs that we've never shared with the world," he said at the time. "We're going to demonstrate that in the Ion."

Click here to listen to a full interview with Cherukuri about thought leadership in Houston, Rice University, and the challenges of advancing research and technology to address society's greatest needs on the Houston Innovators Podcast.

Rice University announced a new partnership between two tech companies to allow for the community to have access to prototyping tools. Photo via Rice

Rice University taps 2 partners to increase access to prototyping technology

3d printing upgrade

A Houston university has entered into partnerships with two businesses to provide on-site prototyping and additive manufacturing services and equipment.

Rice University’s Office of Innovation announced its partnerships with Redwood City, California-based Carbon and Austin, Texas-based manufacturer TyRex Group today. The arrangement includes making additive manufacturing equipment, prototyping, and design facilities and services available on campus.

“Collaboration is the fastest way to get technology out of the lab and into the real world,” says Paul Cherukuri, vice president of innovation at Rice, in a news release, adding that 3D printing "allows you to create things you couldn't otherwise make, and it lets you go very quickly from an idea to a prototype and downstream to a product.”

Carbon's platform — which includes end-use materials, software, and 3D printers — allows users to rapidly design and develop products quickly. At the same time, TyRex’s expertise with manufacturing complements Carbon's technology. Together, the two entities provide the support for turning “proof-of-principle” ideas into viable prototypes.

Cherukuri has first-hand experience with these two businesses, per the release. In 2021, he pitched an idea for 3D-printable smart helmets to the Office of Naval Research. The Rice Smart Helmet reimagines a military helmet that has both protective equipment and a wearable technology platform. The Navy's funding allowed Cherukuri to purchase "two of Carbon’s industrial-grade 3D printers, an M2 model that was installed at Rice for smaller prints and a top-of-the-line, large-format L1 that was installed at TyRex’s Austin facility almost 170 miles from the Rice campus," reads the release.

Cherukuri says the technology allowed the project to “go seamlessly from idea to production,” and he wants to replicate that experience for other labs at Rice. “If I design on the L1, I can hit print and print 1,000 of them, and that is a capability we did not have before,” Cherukuri says in the release.

The technology will be available at the Rice Nexus, based in the Ion and expected to open this summer. Cherukuri recently shared more details on and the potential of the hub on the Houston Innovators Podcast.

"We've got so much technology in our labs that we've never shared with the world," Cherukuri says. "We're going to demonstrate that in the Ion."

The Rice Smart Helmet is an example of the work that can be done through this 3D printing partnership. Photo via Rice.edu

Paul Cherukuri, vice president of innovation at Rice University, joins the Houston Innovators Podcast. Photo via Rice.edu

This Houston innovator is set on bringing more innovation off campus and into the world

houston innovators podcast episode 180

Rice University was founded on a mission of an "unfettered pursuit of knowledge," says Paul Cherukuri, the inaugural vice president for innovation at Rice University. And that goal is specifically designed to be "for the greater good of society," — especially in Houston.

"Rice is right in the middle of one of the greatest cities in the world," Cherukuri says on this week's episode of the Houston Innovators Podcast. "Houston is special on so many levels that it's ridiculous that no one outside of Houston seems to get that. ... We have a moral responsibility as Rice to do more for this city and the country."

Among the top action items on this overarching mission Rice is on is ensuring that the Rice University's inventions and research that have the potential to make the world a better place are able to commercialize to deliver on that impact.

For decades, university research that made it out into the world did so in two ways: papers and patents. While those two avenues are reliable and on going, they take a while. And, as Cherukuri says, the world needs innovative solutions quicker than ever. Cherukuri is focused on expanding those pathways so that more of this innovation — which he describes as invention and commercialization — to come to fruition.

One of the ways Cherukuri is hoping Rice innovators get "beyond the hedges" of the university, as he describes it, is through the Rice Nexus, a hub within the Ion that Cherukuri announced last month. He says Rice is leasing space in the hub, which is owned and operated by Rice Management Company.

"It's a two-way street," Cherukuri says. "We're going to solve problems out in the real world and get those solutions to scale, and we'll be able to find new problems in the real world and bring them inside of Rice and create that new tech. We want to be able to make solutions."

The idea is to create a bridge between the university and the Ion so that more innovation and research can be shared between the campus and Houston's innovation ecosystem.

"We've got so much technology in our labs that we've never shared with the world," Cherukuri says. "We're going to demonstrate that in the Ion."

Also important to Cherukuri is that other universities have a seat at the table, too.

"The Ion represents this catalyst — it's an aggregator and concentrator of excellence for around the city," Cherukuri says. "We're designing the place so that we can connect to the world better."

Hear more of Cherukuri's thought leadership on Houston, Rice University, and the challenges of advancing research and technology to address society's greatest needs on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Rice research breakthrough paves the way for advanced disease therapies

study up

Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”

Greentown Labs names new CEO to lead pioneering climate tech incubator

Transition News

Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

---

This article originally appeared on our sister site, EnergyCapital.

Houston firm invests $150M in leading 'lab on a chip' medical diagnostics co.

fresh funds

Houston-based health technology investment firm Hamershlag Private Capital Management Limited (HPCM) announced a $150.15 million venture investment in Patho Care LLC.

Patho Care is a “lab on a chip” medical diagnostics company known for its noninvasive point-of-care testing platforms, such as its Raman spectroscopy-based platform.

Its digital point-of-care testing devices are programmable, mobile, and reusable and can detect current or future respiratory bacterial or viral infections. The company says the technology is more cost-effective and provides results faster than traditional diagnostic methods.

“Patho Care LLC is a distinguished leader in healthcare diagnostics through the utilization of a novel approach with spectroscopy and this investment aligns with HPCM’s strategy of partnering with high-potential companies in dynamic industries,” L. Mychal Jefferson, Chairman of Hamershlag, said in a news release.

The transaction was structured as an acquisition and recapitalization using newly issued common stock and cash, which will work through a newly formed entity, PathoCare Holdings Inc. The deal will also facilitate the repayment of Patho Care LLC's existing financial obligations and settle Patho Care’s outstanding notes, helping ensure the company’s financial readiness, according to the release.

The investment will help Patho Care LLC improve operational efficiencies, broaden its service offerings and continue to innovate in the diagnostic testing space. The companies hope the collaboration will help “unlock new growth opportunities while maintaining the company’s legacy of excellence in an emerging technology,” according to a news release.

“Our commitment to delivering transformative value through innovative investments underscores our confidence in Patho Care’s vision and capabilities,” Jefferson added.