Silicon Valley fintech company officially opens its second headquarters in Houston

New to town

Bill.com's new Houston office is in West Houston and has space for 125 employees. Natalie Harms/InnovationMap

Only 18 months ago, a growing Palo Alto, Calif.-based fintech company was weighing its options for its first out-of-state expansion. And yesterday, Bill.com opened its second headquarters in Houston.

"When we set out to find a second headquarters in Houston, we had three criteria we were looking for," says René Lacerte, CEO of Bill.com.

Those three things were a good education foundation, vibrant business economy, and diversity, which "Houston has that in spades," Lacerte adds.

Lacerte, who is based in Palo Alto, celebrated the opening of the office on September 18 at a reception that included Mayor Sylvester Turner, Susan Davenport, president of the Greater Houston Partnership, and others who were involved in the process of bring Bill.com to Houston. Mayor Turner even celebrated the office opening by proclaiming September 18th as Bill.com Day in Houston.

"We've worked very hard the past few years to strengthen Houston's digital tech innovation ecosystem," says Davenport. "Today, I think solidifies the momentum we've been building."

The new office is located on the west side of town at the CityWest office development. Bill.com has 25,000 square feet and can have up to 125 employees. Lacerte says he wants to have every department represented in the Houston office, from sales to programming.

"There are two reasons I founded the company," Lacerte says to the crowd. "One was to make a difference in the lives of our customers, and the other was to make a difference in the lives of our employees. Having this second office is a huge opportunity in the lives of people in our communities."

Lacerte founded Bill.com in 2006, and the company has raised over $259 million in funding. The software-as-a-service company has over 3 million members, according to Bill.com, and processes $60 billion in payments annually.

California-based Bill.com is opening its second office in Houston. Photo via Bill.com

Expanding fintech company bets on Houston for second office

Bills, bills, bills

Usually, getting stuck with the bill isn't a good situation to be in, but this is different. Houston just scored the second office of Bill.com, a Palo Alto, Calif.-based business software company. The company decided on Houston because of what the city has to offer both the business and its employees.

"We conducted an extensive national search to select our first location outside the San Francisco Bay Area," says René Lacerte, CEO of Bill.com, in a release from the Greater Houston Partnership. "We're growing at a high speed and it's critical to find the right mix of talent, quality of life and business-friendliness in our next office location. We found all this and more in Houston and are delighted the city can support our next phase of growth."

Planned to open this spring, Bill.com's Houston office will be located on the west side of town at the CityWest development, where it will occupy 25,000 square feet, per the release, and employ 125 people.

"The City of Houston is thrilled to welcome the Bill.com team," says Houston Mayor Sylvester Turner in the release. "We've always been a global and innovative city and the Bill.com announcement is another great example of Houston's building momentum as a leading digital tech hub. We offer a great place to live, work and grow a business, especially for startups and entrepreneurs."

Bill.com was founded in 2006 by René Lacerte and has raised over $259 million in funding. The software-as-a-service company has over 3 million members, according to Bill.com, and processes $60 billion in payments annually.

The Greater Houston Partnership was instrumental in bringing the second Bill.com office to town.

"Houston has always been at the cutting edge of technology — we put a person on the moon and created the first artificial heart, and we continue to build on that legacy," says Susan Davenport, the Greater Houston Partnership's chief economic development officer. "We've been working hard over the last couple of years to develop our community as a hub for digital tech, and the Bill.com expansion here is a validation and confirmation that we've made great progress."

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Houston college joins inaugural workforce accelerator supported by Google

hands-on training

Houston City College (HCC) is one of 15 community colleges from around the country to be selected for the first-ever Workforce Futures Accelerator.

The three-year effort is supported by Google.org, the tech company’s philanthropic arm, and led by the Association of Community College Trustees (ACCT), a non-profit educational organization that represents over 500 community, junior, and technical colleges. The accelerator focuses on helping colleges embed virtual, employer-sponsored training opportunities into short-term workforce training programs, giving participants access to opportunities that they might otherwise receive through internships or other "work-based learning" stints.

"The Workforce Futures Accelerator reflects the Houston City College mission of offering a high-quality, affordable education for workforce training and career development," Pretta VanDible Stallworth, HCC trustee and chair-elect of the ACCT board of directors, said in a news release. "Advancing student success and creating pathways to opportunities ensures that our students are well equipped to succeed and build a secure future in today's economy.”

Through the accelerator, HCC is tasked with fusing online project-based learning opportunities with its workforce education programs. The idea is to give students hands-on experiences working on projects sponsored by employers, allowing them to gain real-world knowledge in the process.

HCC will select two workforce programs that meet the accelerator’s criteria and insert into them into coursework. In the second and third year of the accelerator, the selected colleges are expected to scale the programs by adding instructors and programs to develop a network of to support their continued implementation.

“Participation by HCC will strengthen how we provide students with career-connected learning experiences that complement their classroom education and align with the needs of employers,” HCC Chancellor Margaret Ford Fisher added in the news release. “We are focused on ‘future forward’ strategies to meet the present and future needs of our region’s businesses.”

Two other Texas colleges were chosen to participate in the accelerator: Lamar Institute of Technology in Beaumont and Grayson College in Denison.

The remaining cohort includes:

Bergen Community College in Paramus, New Jersey
Central Louisiana Community College in Alexandria, Louisiana
Clark State College in Springfield, Ohio
Great Basin College in Elko, Nevada
Heartland Community College in Normal, Illinois
Hudson County Community College in Jersey City, New Jersey
Manchester Community College in Manchester, New Hampshire
Mesa Community College in Mesa, Arizona
Mohave College in Kingman, Arizona
San Joaquin Delta Community College in Stockton, California
San Juan College in Farmington, New Mexico
West Virginia University Parkersburg in Parkersburg, West Virginia

New report ranks Texas among top 10 states where AI could disrupt jobs

AI Workforce

A new nationwide report examining where AI could "reshape" the most jobs has ranked Texas No. 9 among the most at-risk states for AI job disruption.

The new SmartAsset report compared all 50 states and the District of Columbia to calculate the estimated percent of the workforce employed in the 26 occupations with the highest AI exposure, as determined by June 2026 research by the Virginia Economic Information and Analytics Division.

The findings revealed that 500,000 Texas workers, or 3.55 percent of the total workforce, are employed in occupations with "high exposure to potential AI disruption."

This also places the Lone Star State as the 9th most at-risk state in the U.S. where AI exposure can lead to "declining hiring demand, wage pressure, task automation, and other forms of disruption."

"States with larger concentrations of highly exposed occupations could experience more pronounced labor-market changes, particularly in roles where core tasks are more vulnerable to AI-driven restructuring," the report's author wrote.

Texas' biggest cities, like Houston and Austin, are known for their thriving tech and business industries, and the study noted that many of the occupations within those sectors are the most at risk. The Virginia Economic Information and Analytics Division said the top five most AI-exposed occupations in the U.S. are: mathematicians, proofreaders, correspondence clerks, court reporters, and media and communication workers. Additionally, computer programmers, database administrators, web developers, telephone operators, and communications equipment operators round out the top 10 most at-risk positions.

These are the 16 remaining occupations most exposed to AI disruption, in order:

Data Entry Keyers
Statistical Assistants
Office Support Workers
Interpreters and Translators
Database Architects
Software Quality Assurance Analysts
Medical Transcriptionists
Software Developers
Writers and Authors
Payroll Clerks
Web Designers
Miscellaneous Computer Occupations
Insurance Claims Processors
Telemarketers
Computer Numerically Controlled Tool Programmers
Bookkeeping and Accounting Clerks

A separate SmartAsset report from April 2026 found about 20.5 percent of Texas workers use AI to do their jobs in some capacity. That trend will continue to shift further as employers and employees choose to adopt — or reject — AI implementation.

Across the U.S., Washington topped the list as the state with the highest concentration of AI-exposed jobs, with nearly 5.7 percent of the state's workforce employed in the 26 most at-risk positions. SmartAsset said Washington's high prevalence of technology companies is a significant factor that skyrocketed the state to the top of the list.

"Home to major technology companies including Microsoft, Amazon, T-Mobile and Expedia, the state has large numbers of computer programmers and software developers, two occupations with high exposure," the report said.

Meanwhile, Mississippi ranked No. 51 with the lowest concentration of AI-exposed jobs in the nation. About 22,500 workers in Mississippi, or 1.93 percent of its workforce, are at risk for AI disruption.

The top 10 states where AI could reshape the most jobs are:

No. 1 – Washington
No. 2 – Virginia
No. 3 – District of Columbia
No. 4 – California
No. 5 – Utah
No. 6 – Maryland
No. 7 – Colorado
No. 8 – New Hampshire
No. 9 – Texas
No. 10 – North Carolina

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This article originally appeared on CultureMap.com.

UH lands $1.2M NIH grant to fight superbugs using AI, quantum sensing

drug defense

The fight against antibiotic-resistant bacteria like MRSA is getting science fiction-like upgrades at the University of Houston thanks to a new four-year, $1.26 million grant from the National Institutes of Health.

The university says the recent funding brings total federal support up to $3.5 million for 11 years for the project, which uses AI and quantum-sensing technology to better understand how bacterial proteins develop resistance to drugs.

Any medical professional will tell you that one of the worst things that can happen is almost killing an infection. Bacteria that survive attacks from conventional antibiotic treatments emerge tougher, more resistant and more aggressive than before–making them much harder to treat. A good example is the superbug methicillin-resistant Staphylococcus aureus (MRSA).

UH chemistry professors Yuhong Wang and Shoujun Xu are working on this issue. They know full well that fighting superbugs requires new technology and new approaches, which is what they aim to pioneer with their new grant.

“Drug-resistant bacterial infections such as MRSA are becoming harder to treat, creating an urgent need for faster ways to understand how antibiotics and other small molecules interact with bacterial proteins,” Wang said in a news release.

Wang and Xu’s work centers around GTP, a cellular fuel that can cause tiny changes to a cell's structure when it mutates. Sometimes, those shape changes make it easier for drugs to breach the wall and attack the cells.

The UH scientists are employing AlphaFold, an AI-powered tool that can scan large molecular libraries in seconds. From these models, they can see promising drug combinations for future testing.

Once identified, the team uses their invention, super-resolution force spectroscopy, to monitor the cells. Tiny magnetic beads are attached to genetic material, then magnified to see how strong that material is when pulled. They can measure this incredible microscopic process through an atomic magnetometer, typically used in quantum physics. Combined, all these tools allow a high-definition look at how each molecule might respond to new chemical approaches.

“We're the only chemists in the world that use an atomic magnetometer for biological research,” Xu said. “It's a technique developed by physicists, and there is usually a gap between techniques developed by physicists and biological applications. Yuhong and I have been bridging that gap together for the past 10 years.”

Eventually, Wang and Xu hope to develop powerful software that can be used by drug manufacturers to model cellular responses. With enough predictive data, the software could even get ahead of superbugs’ own mutation, allowing drugs to be developed before new strains arrive.

"We want an algorithm where you input a protein sequence, score the mutation hotspots, and develop new inhibitors before a drug-resistant species even emerges," Wang added.

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