Houston startup secures bank partnership, energy tech co. wins competition, and more

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CodeLaunch named its winner — and more Houston innovation news. Photo courtesy of Honeycomb

Houston startup founders have been moving and shaking in the local innovation ecosystem — from being recognized for their out-of-this-world innovation to big wins.

In this roundup of Houston startup and innovation news, a Houston company snags a major partnership, an energy tech startup wins big on stage, and more.

The Postage gets a new partner

The Postage platform will be available to AmBank Company's employees, customers, and their families. Photo courtesy of The Postage

A Houston tech platform that streamlines estate and legacy planning has entered into a partnership with AmBank Company — American State Bank, American Investment & Trust, and Perspective Insurance — in Sioux Center, Iowa. The bank will deliver The Postage's services to its employees, customers, and their families.

The Postage unique platform allows users important information organizational tools, as well as state-specific will document creation. The technology also allows users to share meaningful family memories, write future messages, and collaborate with loved ones of their choosing.

"Community is at the core of everything American State Bank does. They exemplify that by supporting their customers through the myriad of choices that arise while navigating their financial lives. The Postage fits right into that, and we are thrilled to share our platform with their employees and customers in their planning and organization efforts," says Emily Cisek, CEO and co-founder of The Postage, in a news release. "We hope to grow awareness of the family-driven digital solution and provide AmBank's customers the opportunity to gain control and safeguard their critical information. We look forward to providing AmBank's customers with the guidance they need to protect their wealth and wisdom now and for generations to come."

The partnership, which rolled out last month, was announced as American State Bank and the family of brands celebrated 50 years of business.

"Our commitment to delivering outstanding service and top-notch products to our customers, colleagues, and community has been unwavering for over half a century," says Joel Westra, AmBank first vice president. "This partnership allows us to extend our digital services while staying true to our core values of connection and community.

"Our team has witnessed the struggles of families coping with losing a loved one, we recognized the need for a service like The Postage," he continues. "Far too often, people are uncertain about the next steps, the whereabouts of important documents, and even their loved one's final wishes. We recognize that to prevent these challenges, families need help navigating difficult conversations and guidance on how to get started with their planning, which The Postage provides."

E360 wins Houston startup competition

E360 and Honeycomb Software share the win at the 2023 Houston CodeLaunch event. Photo by Natalie Harms/InnovationMap

CodeLaunch, a traveling seed-stage accelerator, hosted its second Houston startup pitch competition last week, and a Houston energy efficiency startup emerged victorious.

E360 won the top prize at the event on March 2. The program paired six finalists with consultant development teams to pitch and compete for up to $150,000. The startup's technology is a holistic building solution that monitors both the energy efficiency and indoor air quality of commercial buildings.

“The goal I pursued at CodeLaunch was to meet industry leaders and investors who can help take the product to the next level," says Mat Bonassera, chief enterprise architect at E360, in a news release. “The vast majority of buildings are both incredibly inefficient as well as dangerous to their occupants, due to the dangerous levels of compounds in the air.

"We solve both these complex problems at the same time," he continues. "This is unheard of in our industry. We do this by monitoring vast sums of IOT data and then using Machine Learning and real-time monitoring we adjust the building to optimize its performance. This is a revolutionary way to look at commercial buildings."

E360 shares the win with its partner development team Honeycomb Software, an international custom software development company. The provided hands-on support to E360 scale during a two-day hackathon held February 25 and 26.

“The desire to promote energy efficiency of the buildings and the sustainability in business influenced our decision of whom to work with during the Hackathon," says Oleksandr Semeniuk, CEO of Honeycomb Software, in the release. "Our team worked tirelessly to expand the functionality of E360, and this victory is a testament to their hard work and dedication."

Axiom named among most innovative companies

KBR is one of Axiom Space's partners on its new NASA-sanctioned ISS project. Photo via AxiomSpace.com

Fast Company named it's 50 most innovative companies — and Axiom Space, a Houston-based commercial, full-service orbital mission provider, was named No. 49 on the list. It was also recognized as one of the most innovative space tech companies "for going to space without a chaperone," per the magazine.

The article recognized several of Axiom's accomplishments, including:

  • Managing the first all-private mission to the International Space Station in April of 2022. The mission sent a four-person crew into space for 17 days.
  • Developing plans to expand the international community of space explorers, including Italy, Canada, New Zealand, and others.
  • Building a module to attach to the ISS, which is progress toward the world’s first commercial free-floating space station.

“In the space business, there’s a big focus on the transportation, the rockets,” Michael Suffredini, president and CEO of Axiom, tells Fast Company. “But if you think about the railroads that were built across the U.S., they were built to serve a destination. Without a reason to go somewhere, they wouldn’t exist. We’re building the destination in space—the real estate to allow multiple businesses to operate in low-Earth orbit and take advantage of the microgravity environment.”

NASA also makes the ranking for "showing that a public space program can still do big things," according to the list.

Calling all student-founded startups and businesses

Rice and UH have programs for startup and small business entrepreneurs. Photo via uh.edu

Rice University and the University of Houston have upcoming deadlines for their summer accelerators. The summer programs all operate in coordination with each other and offer support for student, faculty, or staff founders and their startups and small businesses.

The four programs, and their focus and application deadlines, are as follows:

  • Rice's OwlSpark is focused on early-stage startup teams with at least one Rice student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 13.
  • UH's RedLabs is focused on early-stage startup teams with at least one UH student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 31.
  • Rice's BlueLaunch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at Rice. Apply by March 13.
  • UH's Red Launch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at UH. Apply by March 31.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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