CodeLaunch named its winner — and more Houston innovation news. Photo courtesy of Honeycomb

Houston startup founders have been moving and shaking in the local innovation ecosystem — from being recognized for their out-of-this-world innovation to big wins.

In this roundup of Houston startup and innovation news, a Houston company snags a major partnership, an energy tech startup wins big on stage, and more.

The Postage gets a new partner

The Postage platform will be available to AmBank Company's employees, customers, and their families. Photo courtesy of The Postage

A Houston tech platform that streamlines estate and legacy planning has entered into a partnership with AmBank Company — American State Bank, American Investment & Trust, and Perspective Insurance — in Sioux Center, Iowa. The bank will deliver The Postage's services to its employees, customers, and their families.

The Postage unique platform allows users important information organizational tools, as well as state-specific will document creation. The technology also allows users to share meaningful family memories, write future messages, and collaborate with loved ones of their choosing.

"Community is at the core of everything American State Bank does. They exemplify that by supporting their customers through the myriad of choices that arise while navigating their financial lives. The Postage fits right into that, and we are thrilled to share our platform with their employees and customers in their planning and organization efforts," says Emily Cisek, CEO and co-founder of The Postage, in a news release. "We hope to grow awareness of the family-driven digital solution and provide AmBank's customers the opportunity to gain control and safeguard their critical information. We look forward to providing AmBank's customers with the guidance they need to protect their wealth and wisdom now and for generations to come."

The partnership, which rolled out last month, was announced as American State Bank and the family of brands celebrated 50 years of business.

"Our commitment to delivering outstanding service and top-notch products to our customers, colleagues, and community has been unwavering for over half a century," says Joel Westra, AmBank first vice president. "This partnership allows us to extend our digital services while staying true to our core values of connection and community.

"Our team has witnessed the struggles of families coping with losing a loved one, we recognized the need for a service like The Postage," he continues. "Far too often, people are uncertain about the next steps, the whereabouts of important documents, and even their loved one's final wishes. We recognize that to prevent these challenges, families need help navigating difficult conversations and guidance on how to get started with their planning, which The Postage provides."

E360 wins Houston startup competition

E360 and Honeycomb Software share the win at the 2023 Houston CodeLaunch event. Photo by Natalie Harms/InnovationMap

CodeLaunch, a traveling seed-stage accelerator, hosted its second Houston startup pitch competition last week, and a Houston energy efficiency startup emerged victorious.

E360 won the top prize at the event on March 2. The program paired six finalists with consultant development teams to pitch and compete for up to $150,000. The startup's technology is a holistic building solution that monitors both the energy efficiency and indoor air quality of commercial buildings.

“The goal I pursued at CodeLaunch was to meet industry leaders and investors who can help take the product to the next level," says Mat Bonassera, chief enterprise architect at E360, in a news release. “The vast majority of buildings are both incredibly inefficient as well as dangerous to their occupants, due to the dangerous levels of compounds in the air.

"We solve both these complex problems at the same time," he continues. "This is unheard of in our industry. We do this by monitoring vast sums of IOT data and then using Machine Learning and real-time monitoring we adjust the building to optimize its performance. This is a revolutionary way to look at commercial buildings."

E360 shares the win with its partner development team Honeycomb Software, an international custom software development company. The provided hands-on support to E360 scale during a two-day hackathon held February 25 and 26.

“The desire to promote energy efficiency of the buildings and the sustainability in business influenced our decision of whom to work with during the Hackathon," says Oleksandr Semeniuk, CEO of Honeycomb Software, in the release. "Our team worked tirelessly to expand the functionality of E360, and this victory is a testament to their hard work and dedication."

Axiom named among most innovative companies

KBR is one of Axiom Space's partners on its new NASA-sanctioned ISS project. Photo via AxiomSpace.com

Fast Company named it's 50 most innovative companies — and Axiom Space, a Houston-based commercial, full-service orbital mission provider, was named No. 49 on the list. It was also recognized as one of the most innovative space tech companies "for going to space without a chaperone," per the magazine.

The article recognized several of Axiom's accomplishments, including:

  • Managing the first all-private mission to the International Space Station in April of 2022. The mission sent a four-person crew into space for 17 days.
  • Developing plans to expand the international community of space explorers, including Italy, Canada, New Zealand, and others.
  • Building a module to attach to the ISS, which is progress toward the world’s first commercial free-floating space station.

“In the space business, there’s a big focus on the transportation, the rockets,” Michael Suffredini, president and CEO of Axiom, tells Fast Company. “But if you think about the railroads that were built across the U.S., they were built to serve a destination. Without a reason to go somewhere, they wouldn’t exist. We’re building the destination in space—the real estate to allow multiple businesses to operate in low-Earth orbit and take advantage of the microgravity environment.”

NASA also makes the ranking for "showing that a public space program can still do big things," according to the list.

Calling all student-founded startups and businesses

Rice and UH have programs for startup and small business entrepreneurs. Photo via uh.edu

Rice University and the University of Houston have upcoming deadlines for their summer accelerators. The summer programs all operate in coordination with each other and offer support for student, faculty, or staff founders and their startups and small businesses.

The four programs, and their focus and application deadlines, are as follows:

  • Rice's OwlSpark is focused on early-stage startup teams with at least one Rice student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 13.
  • UH's RedLabs is focused on early-stage startup teams with at least one UH student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 31.
  • Rice's BlueLaunch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at Rice. Apply by March 13.
  • UH's Red Launch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at UH. Apply by March 31.

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CultureMap Emails are Awesome

6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston Community College, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

Texas-based energy startup raises $1 billion on heels of Houston expansion

Powering Up

Austin-based startup Base Power, which offers battery-supported energy in the Houston area and other regions, has raised $1 billion in series C funding—making it one of the largest venture capital deals this year in the U.S.

VC firm Addition led the $1 billion round. All of Base Power’s existing major investors also participated, including Trust Ventures, Valor Equity Partners, Thrive Capital, Lightspeed Venture Partners, Andreessen Horowitz (a16z), Altimeter, StepStone Group, 137 Ventures, Terrain, Waybury Capital, and entrepreneur Elad Gil. New investors include Ribbit Capital, Google-backed CapitalG, Spark Capital, Bond, Lowercarbon Capital, Avenir Growth Capital, Glade Brook Capital Partners, Positive Sum and 1789 Capital Management.

Coupled with the new $1 billion round, Base Power has hauled in more than $1.27 billion in funding since it was founded in 2023.

Base Power supplies power to homeowners and the electric grid through a distributed storage network.

“The chance to reinvent our power system comes once in a generation,” Zach Dell, co-founder and CEO of Base Power, said in a news release. “The challenge ahead requires the best engineers and operators to solve it, and we’re scaling the team to make our abundant energy future a reality.”

Zach Dell is the son of Austin billionaire and Houston native Michael Dell, chairman and CEO of Round Rock-based Dell Technologies.

In less than two years, Base Power has developed more than 100 megawatt-hours of battery-enabled storage capacity. One megawatt-hour represents one hour of energy use at a rate of one million watts.

Base Power recently expanded its service to the city of Houston. It already was delivering energy to several other communities in the Houston area. To serve the Houston region, the startup has opened an office in Katy.

The startup also serves the Dallas-Fort Worth and Austin markets. At some point, Base Power plans to launch a nationwide expansion.

To meet current and future demand, Base Power is building its first energy storage and power electronics factory at the former downtown Austin site of the Austin American-Statesman’s printing presses.

“We’re building domestic manufacturing capacity for fixing the grid,” Justin Lopas, co-founder and chief operating officer of Base Power, added in the release. “The only way to add capacity to the grid is [by] physically deploying hardware, and we need to make that here in the U.S. ... This factory in Austin is our first, and we’re already planning for our second.”

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This article originally appeared on EnergyCapitalHTX.com.