After the floods from Hurricane Harvey totaled her car, Rahel Abraham wanted to find a solution. ClimaGuard/Facebook

Floodwaters from Hurricane Harvey seriously damaged about 600,000 vehicles in the Houston area, driving millions upon millions of dollars in auto insurance claims. Rahel Abraham's 2008 Infiniti G35 was among them.

Rather than merely moving on from the hurricane, though, Abraham — drawing upon her experience as an engineer in Houston's petrochemical industry — invented something that she foresaw shielding cars from the economic wrath of flooding.

Now, Abraham's brainchild forms the backbone of her Houston-based startup, ClimaGuard LLC. The next several weeks promise to be momentous for the business — Abraham will enter the 12-week DivInc business accelerator program in Austin in late August, and the company's first product is set to hit the market in early September.

ClimaGuard's waterproof, temperature-resistant, portable Temporary Protective Enclosure (TPE) can entirely cover a compact car, sedan, or midsize SUV. It comes in three sizes; the cost ranges from $349 to $499.

To protect a vehicle, someone sets a TPE on the ground, a driveway, or another flat surface, then drives the vehicle onto the bottom part of the product, and connects the bottom and top parts with the zipper. Abraham likens it to a clamshell preserving a pearl.

Once the vehicle is inside the TPE, it can be anchored with straps to a sturdy fixture. It's designed to withstand up to three feet of water and keep the vehicle from floating away.

One person can set up a TPE in less than five minutes, Abraham says.

She hopes to team up with auto insurers to offer discounts for policyholders that have a TPE. This, Abraham says, would spur more people to buy the product.

"My goal is not to make it to where it's an exclusive product — available only to those who can afford it — but I want to be able to help those who it would make even more of an economic impact for," Abraham says.

Among potential customers for the TPE are car owners, homeowners, small businesses, first-responder organizations, and nonprofit agencies, Abraham says. Other than vehicles, the product could protect valuables like antique pianos and restaurant gear, according to Abraham.

The sense of "helplessness and vulnerability" Abraham felt after her car was lost in Hurricane Harvey propelled her to devise ClimaGuard's TPE, she says, so that others might avoid enduring the sort of "stressful and traumatic" ordeal that she did.

Another catalyst: After hatching the idea for the TPE, Abraham learned that more than 41 million Americans live in federally designated flood zones, and that flooding is the costliest type of natural disaster in the U.S. and is forecast to occur more frequently. That research "validated my gut feeling," she says.

Abraham, a first-time entrepreneur, founded the bootstrapped startup in 2018, just a year after Harvey. Today, she's the only full-time employee of ClimaGuard. She holds a bachelor's in chemical engineering from the University of Texas at Austin and a master's degree in environmental engineering from the University of Houston.

Abraham says she hopes participating in the 12-week DivInc accelerator program in Austin will broaden her business network and hone her marketing skills. ClimaGuard was among 13 companies selected for this fall's DivInc group, which is sponsored by JPMorgan Chase.

DivInc aims to diversify the startup environment by offering workshops, mentoring, and business-strategy assistance to underrepresented entrepreneurs — people of color and women. The Austin-based nonprofit organization chooses participants through an application process that its program director, Brooke Turner, describes as being "extremely competitive" this year.

"It's tough being a developer or entrepreneur when no one looks like you when you walk into a room of other developers or entrepreneurs," DivInc co-founder Ashley Jennings told Crunchbase in 2017. "How can they feel that they fit in? So what we have now is an opportunity to create role models with this generation."
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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.