This week's roundup of Houston innovators includes Ryan Sitton of Pinnacle, Julia P. Clarke of Raba Kistner Inc., and Phillip Yates of Equiliberty. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data analysis to fintech — recently making headlines in Houston innovation.

Ryan Sitton, CEO of Pinnacle

Ryan Sitton joins the Houston Innovators Podcast to discuss his career in data and reliability. Photo courtesy of Ryan Sitton

Data analysis for big industry came first — before the technology that can support this analysis even entered the scene. Ryan Sitton, CEO and founder of Pinnacle, a Houston company that offers its clients streamline data management, joined the Houston Innovators Podcast to discuss his passion is using data to drive better decision making to drive more sustainable and reliable operations.

"I was basically doing data analytics in the mid 2000s before it was sexy. I was pulling together data in chemical plants and refineries and trying to predict how these plants would behave with the data I had," Sitton says. "I realized early on how there was so much opportunity here — but we don't have the technologies or the methodology to do it."

But over the years, the technology has caught up and now Sitton is able to provide clients with even more data-driven solutions. Click here to read more.

Julia P. Clarke, senior geotechnical manager in Houston at Raba Kistner Inc.

Julia P. Clarke knows what it's like to be the only woman in a room. Photo courtesy of Raba Kistner

Women in STEM are in Houston, writes Julia P. Clarke, an engineer at a local firm in town, but there's work to be done to making them stay. Supporting women across the science, technology, engineering, and mathematics fields begins in the classroom, she writes in a guest column for InnovationMap.

"I grew up in Jamaica and then immigrated to the United States. It wasn't until I was recognized by my high school teacher, Mrs. Owens, for my natural ability to excel in subjects like science and math that I fell in love with the basis of engineering," she explains. "Without the mentorship and investment of teachers and professionals throughout my career, I would not be where I am today." Click here to read more.

Phillip Yates, founder of Equiliberty

This founder is bridging the wealth gap for Black Houstonians. Photo courtesy of Equiliberty

Phillip Yates, a Houston-area attorney, envisioned a company that could solve the societal problems that perpetuate poverty. He started Equiliberty, a technology company that's part financial resource and part social network, to help provide underrepresented individuals with educational resources to secure financial success and a space to use their talents to create community-driven wealth.

The platform provides business development services, educational resources, access to capital, and mentorship to help users find financial independence.

"When I created Equiliberty, I envisioned a world where everybody has access to mentors," said Yates in a press release. "I know firsthand the importance of having a supportive network and community dedicated to your success." Click here to read more.

Female engineers are here in Houston, but let's work together to ensure they are here to stay. Photo via Christina Morillo/Pexels

How to attract and retain female engineers for the Houston workforce

guest column

As Houston continues to invest in resiliency for our growing city, a well-equipped workforce is needed to meet the demand for critical infrastructure. It is also important that in a city as diverse as Houston, the engineering and construction talent that encompasses our workforce is reflective of the city itself, aligning with our ever-changing demographics.

While women continue to make strides in the STEM field, according to Pew Research Center, women's shares in the field of engineering have inched up only slightly, from 12% in 1990 to 15% today. And while women now earn a majority of all undergraduate and advanced degrees, they remain a small share of degree earners in fields like engineering and computer science — areas where they are significantly underrepresented in the workforce.

Diversity yields creativity, and women bring a valuable and unique perspective to problem solving and innovation. I grew up in Jamaica and then immigrated to the United States. It wasn't until I was recognized by my high school teacher, Mrs. Owens, for my natural ability to excel in subjects like science and math that I fell in love with the basis of engineering. Without the mentorship and investment of teachers and professionals throughout my career, I would not be where I am today.

In Houston, it is not a question of talent — we have plenty of diverse talent, and many young women entering the engineering workforce. The issue we run into is keeping them here and elevating them to reach the pinnacle of their discipline.

If we want to inspire young women to join the field, and ensure more women remain in it, we need to invest in mentor relationships and create space and opportunities for successful women to grow into positions of leadership.

Invest

Many would agree that mentorship plays a key role in career growth and development, but we need to be specific about what that means and how to do it effectively. For a mentor relationship to be impactful, it needs to be continuous and personal. When girls are in grade school, they are impressionable and open to inspiration. We have the opportunity to help them build confidence and make a difference in their futures.

It is important to remember that women will need several mentors throughout their lives. Obtaining an engineering degree is not easy, and upon graduation, young professionals come to the realization that what was taught in school can be different from what a job requires. New mentors are needed throughout the many seasons of personal and professional growth, and it is the responsibility of successful women engineers to take the time to develop true, lasting relationships with the next generation. We need more individuals who are willing to reach out to young women at a relatable level and establish that personal touch.

Inspire

Once we have women committed to a career in engineering, how do we foster them to go further in the field? We need more females in leadership roles. The high school teacher I mentioned was female and African American. Being able to relate to her eliminated barriers for me. I told myself that if she can do this, and she believes in me and looks like me, then I can do this, too. Young women and professionals need to be able to look at a company or professional organization's board members and executives and see faces that look like their own.

Listen

Last year, over 20 million Americans were out of work due to COVID-19, yet as the pandemic eases, millions of women have yet to return to the workplace. While this may be due to a complex mix of factors, I am left wondering if business leaders are actually asking women why they haven't returned. Many companies make assumptions regarding women's priorities, needs and expectations, without having a conversation. We are left with a shortage in our workforce, which will impact Houston sooner than most cities, and there needs to be an open dialogue between businesses and women to discover what they need to be successful.

Lastly, as women, it is our responsibility to use our voice. If I were to have let the assumptions of others guide my life and career path, I would not be where I am today. If you can persist and you are resilient, you will succeed. Women are here, but let's work together to ensure they are here to stay.

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Julia P. Clarke is senior geotechnical manager in Houston at Raba Kistner, Inc., an engineering consulting and program management firm based in San Antonio.

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Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

Houston quantum energy chip startup emerges from stealth with $12M round

seed funding

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip.

The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target, according to a news release.

Casimir’s semiconductor chips can generate power from quantum vacuum fields without the need for batteries or charging. The company plans to commercialize its first-generation MicroSparc chip by 2028.

The MicroSparc chip measures 5 millimeters by 5 millimeters and is designed to produce 1.5 volts at 25 microamps, comparable to a small rechargeable battery, without degradation and no replacement cycle.

“Casimir represents exactly the kind of breakthrough dual-use technology Scout Ventures was built to back,” Brad Harrison, founder and managing partner at Scout Ventures, said in the release. “This is based on 100 years of science and we’re finally approaching a commercial product … We’re proud to lead this round and support Casimir’s journey from applied science to deployed technology.”

Casimir says it aims to scale its technology across the ”full power spectrum,” including large-scale energy systems that can power homes, commercial infrastructures and electric vehicles.

Casimir's scientific work has been supported by DARPA-funded nanofabrication research and its technology was incubated at the Limitless Space Institute (LSI). LSI is a nonprofit that works to innovate interstellar travel and was founded by Kam Ghaffarian. Technology investor and serial entrepreneur Ghaffarian has been behind companies like X-energy, Intuitive Machines, Axiom Space and Quantum Space.

Harold “Sonny” White, founder and CEO of Casimir, believes the technology can power devices for years without replacements.

“Millions of devices will operate for years without a battery ever needing to be replaced or recharged because we have engineered a customized Casimir cavity into hardware capable of producing persistent electrical power,” White added in the release. “I spent nearly two decades at NASA studying how we power humanity’s future. That work led me to the Casimir effect and the quantum vacuum, where new tools have allowed us to build on a century of scientific knowledge and bring abundant power to the world.”