3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Ryan Sitton of Pinnacle, Julia P. Clarke of Raba Kistner Inc., and Phillip Yates of Equiliberty. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data analysis to fintech — recently making headlines in Houston innovation.

Ryan Sitton, CEO of Pinnacle

Ryan Sitton joins the Houston Innovators Podcast to discuss his career in data and reliability. Photo courtesy of Ryan Sitton

Data analysis for big industry came first — before the technology that can support this analysis even entered the scene. Ryan Sitton, CEO and founder of Pinnacle, a Houston company that offers its clients streamline data management, joined the Houston Innovators Podcast to discuss his passion is using data to drive better decision making to drive more sustainable and reliable operations.

"I was basically doing data analytics in the mid 2000s before it was sexy. I was pulling together data in chemical plants and refineries and trying to predict how these plants would behave with the data I had," Sitton says. "I realized early on how there was so much opportunity here — but we don't have the technologies or the methodology to do it."

But over the years, the technology has caught up and now Sitton is able to provide clients with even more data-driven solutions. Click here to read more.

Julia P. Clarke, senior geotechnical manager in Houston at Raba Kistner Inc.

Julia P. Clarke knows what it's like to be the only woman in a room. Photo courtesy of Raba Kistner

Women in STEM are in Houston, writes Julia P. Clarke, an engineer at a local firm in town, but there's work to be done to making them stay. Supporting women across the science, technology, engineering, and mathematics fields begins in the classroom, she writes in a guest column for InnovationMap.

"I grew up in Jamaica and then immigrated to the United States. It wasn't until I was recognized by my high school teacher, Mrs. Owens, for my natural ability to excel in subjects like science and math that I fell in love with the basis of engineering," she explains. "Without the mentorship and investment of teachers and professionals throughout my career, I would not be where I am today." Click here to read more.

Phillip Yates, founder of Equiliberty

This founder is bridging the wealth gap for Black Houstonians. Photo courtesy of Equiliberty

Phillip Yates, a Houston-area attorney, envisioned a company that could solve the societal problems that perpetuate poverty. He started Equiliberty, a technology company that's part financial resource and part social network, to help provide underrepresented individuals with educational resources to secure financial success and a space to use their talents to create community-driven wealth.

The platform provides business development services, educational resources, access to capital, and mentorship to help users find financial independence.

"When I created Equiliberty, I envisioned a world where everybody has access to mentors," said Yates in a press release. "I know firsthand the importance of having a supportive network and community dedicated to your success." Click here to read more.

Female engineers are here in Houston, but let's work together to ensure they are here to stay. Photo via Christina Morillo/Pexels

How to attract and retain female engineers for the Houston workforce

guest column

As Houston continues to invest in resiliency for our growing city, a well-equipped workforce is needed to meet the demand for critical infrastructure. It is also important that in a city as diverse as Houston, the engineering and construction talent that encompasses our workforce is reflective of the city itself, aligning with our ever-changing demographics.

While women continue to make strides in the STEM field, according to Pew Research Center, women's shares in the field of engineering have inched up only slightly, from 12% in 1990 to 15% today. And while women now earn a majority of all undergraduate and advanced degrees, they remain a small share of degree earners in fields like engineering and computer science — areas where they are significantly underrepresented in the workforce.

Diversity yields creativity, and women bring a valuable and unique perspective to problem solving and innovation. I grew up in Jamaica and then immigrated to the United States. It wasn't until I was recognized by my high school teacher, Mrs. Owens, for my natural ability to excel in subjects like science and math that I fell in love with the basis of engineering. Without the mentorship and investment of teachers and professionals throughout my career, I would not be where I am today.

In Houston, it is not a question of talent — we have plenty of diverse talent, and many young women entering the engineering workforce. The issue we run into is keeping them here and elevating them to reach the pinnacle of their discipline.

If we want to inspire young women to join the field, and ensure more women remain in it, we need to invest in mentor relationships and create space and opportunities for successful women to grow into positions of leadership.

Invest

Many would agree that mentorship plays a key role in career growth and development, but we need to be specific about what that means and how to do it effectively. For a mentor relationship to be impactful, it needs to be continuous and personal. When girls are in grade school, they are impressionable and open to inspiration. We have the opportunity to help them build confidence and make a difference in their futures.

It is important to remember that women will need several mentors throughout their lives. Obtaining an engineering degree is not easy, and upon graduation, young professionals come to the realization that what was taught in school can be different from what a job requires. New mentors are needed throughout the many seasons of personal and professional growth, and it is the responsibility of successful women engineers to take the time to develop true, lasting relationships with the next generation. We need more individuals who are willing to reach out to young women at a relatable level and establish that personal touch.

Inspire

Once we have women committed to a career in engineering, how do we foster them to go further in the field? We need more females in leadership roles. The high school teacher I mentioned was female and African American. Being able to relate to her eliminated barriers for me. I told myself that if she can do this, and she believes in me and looks like me, then I can do this, too. Young women and professionals need to be able to look at a company or professional organization's board members and executives and see faces that look like their own.

Listen

Last year, over 20 million Americans were out of work due to COVID-19, yet as the pandemic eases, millions of women have yet to return to the workplace. While this may be due to a complex mix of factors, I am left wondering if business leaders are actually asking women why they haven't returned. Many companies make assumptions regarding women's priorities, needs and expectations, without having a conversation. We are left with a shortage in our workforce, which will impact Houston sooner than most cities, and there needs to be an open dialogue between businesses and women to discover what they need to be successful.

Lastly, as women, it is our responsibility to use our voice. If I were to have let the assumptions of others guide my life and career path, I would not be where I am today. If you can persist and you are resilient, you will succeed. Women are here, but let's work together to ensure they are here to stay.

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Julia P. Clarke is senior geotechnical manager in Houston at Raba Kistner, Inc., an engineering consulting and program management firm based in San Antonio.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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