When approaching prototype creation, you must make a series of decisions. This expert weighs in with her expertise. Photo courtesy

When embarking on the journey of developing and bringing a new product to the market, you as an inventor have to consider a multitude of aspects that add to the overall market success of your final product. And prototyping is one of the key product development stages that helps you achieve that.

Whether you're going to launch a hardware or a software product, or the combination of both — you need to have a prototype made. First, it allows you to validate your idea and see if it's worth investing time and money into. Second, it creates opportunities for product improvement, detection and elimination of design flaws, and cost reduction, especially during manufacturing.

Therefore, you will need to make a set of choices before you actually build a prototype to ensure that it results in a viable, cost-effective, and quality market-ready product. Let's look at major choice points and their implications that will help you navigate the process in the most efficient way.

To begin, let's look at the various options you have.

The success of any process lies in its foundation. Hence, before anything else you need to decide on the product development approach you're going to follow. Some inexperienced inventors, for instance, choose to go from product idea straight to having a prototype made. They skip three initial steps that are crucial for building a sound road map of the development process and creating a product with a maximum market potential.

In most cases, those inventors end up coming to companies that build prototypes to start from scratch. Usually, it's because they hit a dead end with their prototype or a product was manufactured with many defects. The latter is always a result of improperly optimized pre-production prototype, if optimized at all.

The extensive experience of our product development team shows that a methodological approach to the entire process, prototyping in particular, yields the most effective results. That's why we always recommend it to those inventors who choose to DIY their prototype. If you're one of them, here is a short version of the approach with steps it implies that you can use prior to prototyping. You can find the in-depth version here.

1. Product discovery

To set the path for the development of your idea you need to identify your product's strengths, weaknesses, opportunities, and threats. In other words, you need to conduct a SWOT analysis, which will help you learn about:

  • intellectual property opportunities
  • your competition and target market
  • features your product should have
  • time and cost of your idea development.

2. Concept design

Based on the results of the SWOT analysis, you can establish the road map of the development of your product and get to creating a concept or industrial design. Concept design is a virtual representation of your idea translated into 2D renderings and 3D CAD models that show you a rough look and functions your product will have. These should be built in accordance with preferences of your target audience to ensure the product's market fit. Concept design is usually made by a professional Industrial Designer. But if you have a basic knowledge of how to use industrial design software applications, then you can make it yourself.

3. Market and prior art research 

Another important step before prototyping is gathering and analyzing feedback from potential consumers. This is done through market research. With a concept design developed, you can conduct focus groups and consumer surveys to understand if the audience likes your idea. The information you get will give you more opportunities to improve your idea and add necessary changes to the design before prototyping, thus reducing the cost of the process and increasing market potential.

Prior Art Search, or research of existing patents, provides some of the benefits as market research. But its main purpose is to identify similar product ideas that have already been patented, so that you can make your product stand out by adding unique features to the design, as well as avoid a conflict of patent rights.

In a follow up article next week, we will discuss more decisions you must make during the prototype process. I have also previously contributed to guest columns on the following:

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Onega Ulanova is the founder of OKGlobal.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.