Photo courtesy of Greentown Labs

An accelerator focused on supporting BIPOC-led climatetech startups and addressing inequities in the climatetech industry is accepting applications for its second cohort.

Greentown Labs, the largest climatetech incubator in North America, and Browning the Green Space (BGS), a nonprofit dedicated to making clean energy and other climate-related fields more diverse, equitable, and inclusive, lead the Advancing Climatetech and Clean Energy Leaders Program (ACCEL), which offers access to funding, networking connections, resources, and opportunities that structural inequities put out of reach.

“Opening applications for Year 2 of ACCEL is an important milestone in strengthening critical support for traditionally excluded entrepreneurs in our communities,” says Kerry Bowie, executive director and president of Browning the Green Space.

Benefits for startups accepted into the ACCEL program include:

  • gaining access to extensive mentorship from industry experts
  • $25k in non-dilutive grant funding
  • a curated curriculum of workshops led by experts — including from VentureWell — covering various essential topics for early-stage climatetech founders, such as customer discovery, design-thinking, startup finance, storytelling, and more

“Through our partnership with Greentown and VentureWell, we are able to put our respective strengths together to create an ambitious program to bolster founders of color in climatetech and propel innovations that benefit communities most impacted by climate change,” Bowie says.

For Year 2 of ACCEL, Greentown and BGS are seeking applications from startups at Technology Readiness Levels (TRL) 1-4 that are developing climate solutions for the electricity, transportation, buildings, manufacturing, agriculture, and resiliency and adaptation sectors. Applications are due January 5, 2024.

The Year 2 request for applications comes as a successful inaugural year of ACCEL winds to a close.

ACCEL Year 1 featured six startups working on innovations as diverse as sneakers made from food waste, ultracapacitors built with hemp sourced from Black and Indigenous farmers, and ultra-light solar panels.

Their accomplishments during the accelerator included raising equity funding, earning acceptances into additional accelerators, winning grants, executing customer discovery, and more. Check out more results from Year 1 of ACCEL here.

“ACCEL is one of the most impactful, meaningful programs we’ve run to date,” says Greentown Labs CEO and president Kevin Knobloch. “We are eager to expand upon the great success and momentum of Year 1, and to welcome another incredible cohort of BIPOC-led startups that are developing much-needed climatetech solutions. We’re equally committed to helping these companies accelerate and deploy their solutions, while also helping to build a more diverse, inclusive climatetech workforce — ACCEL sits at the nexus of those two critical efforts.”

Apply for ACCEL Year 2 here and sign up for program updates here.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”