Grace Rodriguez, CEO and executive director of Impact Hub Houston, has a few weeks ahead of her. Courtesy of Grace Rodriguez

Impact Hub Houston — the local chapter of a nonprofit focused on supporting startups in the social impact space — has a lot on its plate this month.

Not only is next week The Houston Innovation Summit — the fourth annual week of entrepreneurship programming — as well as the second annual Climathon, but the organization has also just launched a new business incubator program.

Accelerate is a program that Impact Hub has offered across 17 international markets. Houston's new chapter already has a few Houston startups involved — including Potentia Workforce and McMac CX. Structured as an ongoing accelerator with mentorship, education, and support, the program is currently accepting new members.

"We actually sit down with each new Accelerate member and then go through a diagnostic interview to help them understand what stage they're at," says Grace Rodriquez, CEO and executive director of Houston Impact Hub. "And then we create a development strategy with them."

Whether the Accelerate member needs one-on-one mentorship, specialized education, or more, the program match makes each member's needs. EY is a network partner and — since everything is virtual — member companies have access to international experts through Impact Hub and its partners' networks.

"The ideal entrepreneur for the Accelerate membership is somebody who has already developed a solution — at least an MVP — for their social venture, whether it's a product or a service," Rodriguez says.

She cites Potentia as an example. The startup helps find jobs for adults with special needs, as well as educate corporations on how to work with and collaborate with these individuals. The company already has data and momentum, and the Accelerate program is helping the company to get to it's next stage.

"The idea is that we help people ladder up — no matter what stage you're at," Rodriguez says.

While growing the new program's membership — Rodriguez says it's her goal to get to 10 member companies my early next year — she's also focused on The Houston Innovation Summit and Impact Hub's Climathon.

The second annual Climathon, which begins Friday, November 13, has evolved since last year in a number of ways. First of all, it's completely virtual — which poses its own set of challenges and opportunities. Additionally, the event has several new partners — most of which didn't even exist in Houston last year, like Greentown Houston and Evolve Houston.

One of the biggest, most exciting changes for Rodriguez is the structure. While last year's event functioned as a hackathon, this year attendees can expect thought-provoking programming and collaboration.

"Last year, [Climathon] was directed at people who were more tech savvy," Rodriguez says. "What we found is people who are interested in climate action are a lot of times policy oriented or community activists and they don't know how they can plug into the tech space. It's more of an idea-a-thon. You don't have to develop a tech solution, but we can think about how we can activate more people for climate change."

Last year's Climathon took place during October. WIth it moving to November this year, it coincides with THIS, adding even more events to the week-long, impact-focused summit. THIS, which was designed to run alongside Global Entrepreneurship Week, also considers that week's themes, which are: education, ecosystems, inclusion, and policy.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions."

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European spacecraft developer expands to Houston with U.S. business, new lab

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European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.