From robotics to artificial intelligence, here's how Amazon gets its products to Houstonians in record time. Photo by Natalie Harms/InnovationMap

Last summer, Amazon opened the doors to its North Houston distribution center — one of the company's 50 centers worldwide that uses automation and robotics to fulfill online orders.

The Pinto Business Park facility has millions of products in inventory across four floors. Products that are 25 pounds or less (nothing heavier is stocked at this location) pass through 20 miles of conveyor belts, 1,500 employees, and hundreds of robots.

The center also has daily tours open to the public. We recently visited to see for ourselves the process a product goes through at this Houston plant. From stowing to shipping, here's how packages go from your shopping cart to your front porch.

Starting with stowing 

Natalie Harms/InnovationMap

A product's first step in an Amazon facility is stowing. There's no categorization of the products — it's not like there's one floor for one type of item or anything.

"It's completely randomly stowed," says Donna Beadle, PR specialist for Amazon. "She could be stowing cat food on this floor, and so could somebody on floor two."

An Amazon employee would scan an item and stow it into an empty bin of her choosing — sort of. To prevent confusion, a light projected indicates bins that are off limits to stow the item. The light identifies bins that have similar products. Keeping similar products apart helps prevents mistakes for the employee who later pulls those items once its ordered.

The system also sees where the employee is putting each item, rather than having to scan each item and the bin as well. This is a newer feature — the facility originally opened with hand-held scanners.

"Our next generation workstation is that they don't have to hold that scanner — they have hands free," says Brenda Alford, regional communications manager at Amazon.

Robots on the move

Once the bins are fully stocked, the robot — which is the orange device on the bottom of the yellow bins — moves about the facility by scanning QR codes on the floor.

Should a product fall out, an employee wearing a special vest can enter to retrieve it. That vest will send off a signal to the robots, which will then decrease their speeds and come to a stop when the employee comes close.

"It's an extra measure of safety so that people can interact with the robots and feel safe," says Beadle.

Picking before packing

Natalie Harms/InnovationMap

Once an item is ordered, the bin with that item appears in the pick process at the center. The system tells the Amazon employee which item to grab and which bin to put it in. The bins will have products for multiple different orders — another employee later will separate it out later.

"Often we describe it as a symphony — our technology and our associates working together," Alford says, noting that sometimes the company might receive criticism about using robots over humans. "We can't do this without these humans.

Amazon employees receive their benefits from day one on the job, Beadle says, and they work four, 10-hour days a week.

"We feel like that way they have more time with their families — they get three days off versus two days off. And that gives them time to heal and rest up," she says.

Bin to bin and back again

Natalie Harms/InnovationMap

Once full, the Amazon associate will push the bin onto a series of conveyor belts. The whole facility has 20 miles of conveyor belts — much of which happens overhead.

The bins then zigzag toward the pack process, which is separated to different stations. There are single-product stations and multiple package stations. The system determines where the bin should go, and some stations pack products that are determined to need packing materials, while others do not.

Single-product packaging

Natalie Harms/InnovationMap

At the packing process, the Amazon employee is told which size box to assemble — he or she can grab a bigger box, but they can't select a smaller one. The tape dispenser doles out the correct size of tape for that box automatically.

Once packaged up, a sticker with a barcode is placed on the box. This code will later be used to print the label for shipping. At this point in the process, no personal information has been revealed to anyone. In fact, most packages leave the facility without any personal information being viewed by employees.

In an effort to reduce packing materials, some products are shipped in the container they came in. In that instance, the packer would just place the barcode sticker on the package before sending it on the conveyor belt.

"If we don't need another box for that product, we don't use one," Beadle says. "We work with companies to make that happen, so we don't have to use more boxes if we don't have to."

SLAM 


While the robotics aren't slamming labels on packages, the SLAM process (short for scan, label, apply and manifest) is the first step in the process that includes a customer's personal information. During this process, the barcode is scanned, the package is weighed, and the label is printed and affixed to the package using a puff of air.

A package might be automatically pulled from the line if something seems to be off in the package's weight.

"Say you bought toothpaste, and it says that toothpaste weighs 20 pounds, we know something's wrong," Beadle says. "Like maybe that it was a pack that didn't get separated."

If the package is kicked off, an Amazon associate, called a problem solver, will assess the situation and make it right before returning it to the conveyor belt.

Kicked into gear

Once labeled, all the packages are sent on their final conveyor belt ride. Using a scanning process, the packages are kicked by an automated foot that sends them into a line to be loaded into an Amazon truck.

If a package misses its chute the first time around, it makes the loop again. The system can tell if a package is caught in the loop for whatever reason, and a problem solver might be called to assess the situation.

Down the slide

Natalie Harms/InnovationMap

After being kicked off the belt, the package then slides down a spiral chute that, despite looking like a playground slide, is off limits to any humans wanting to keep their job.

"People ask if you can go down the slide, and we always say that on your last day of work," Beadle jokes.

On to the shipping process

Natalie Harms/InnovationMap

The packages leave the facility in Amazon trucks and head to one more pit stop before making it to the customer.

"They don't go directly to your house after this process," Beadle says. "They go to a sortation center."

This could mean a USPS or UPS stop, but it depends on where the customer lives.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.