3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Ryan Sitton of Pinnacle, Julia P. Clarke of Raba Kistner Inc., and Phillip Yates of Equiliberty. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data analysis to fintech — recently making headlines in Houston innovation.

Ryan Sitton, CEO of Pinnacle

Ryan Sitton joins the Houston Innovators Podcast to discuss his career in data and reliability. Photo courtesy of Ryan Sitton

Data analysis for big industry came first — before the technology that can support this analysis even entered the scene. Ryan Sitton, CEO and founder of Pinnacle, a Houston company that offers its clients streamline data management, joined the Houston Innovators Podcast to discuss his passion is using data to drive better decision making to drive more sustainable and reliable operations.

"I was basically doing data analytics in the mid 2000s before it was sexy. I was pulling together data in chemical plants and refineries and trying to predict how these plants would behave with the data I had," Sitton says. "I realized early on how there was so much opportunity here — but we don't have the technologies or the methodology to do it."

But over the years, the technology has caught up and now Sitton is able to provide clients with even more data-driven solutions. Click here to read more.

Julia P. Clarke, senior geotechnical manager in Houston at Raba Kistner Inc.

Julia P. Clarke knows what it's like to be the only woman in a room. Photo courtesy of Raba Kistner

Women in STEM are in Houston, writes Julia P. Clarke, an engineer at a local firm in town, but there's work to be done to making them stay. Supporting women across the science, technology, engineering, and mathematics fields begins in the classroom, she writes in a guest column for InnovationMap.

"I grew up in Jamaica and then immigrated to the United States. It wasn't until I was recognized by my high school teacher, Mrs. Owens, for my natural ability to excel in subjects like science and math that I fell in love with the basis of engineering," she explains. "Without the mentorship and investment of teachers and professionals throughout my career, I would not be where I am today." Click here to read more.

Phillip Yates, founder of Equiliberty

This founder is bridging the wealth gap for Black Houstonians. Photo courtesy of Equiliberty

Phillip Yates, a Houston-area attorney, envisioned a company that could solve the societal problems that perpetuate poverty. He started Equiliberty, a technology company that's part financial resource and part social network, to help provide underrepresented individuals with educational resources to secure financial success and a space to use their talents to create community-driven wealth.

The platform provides business development services, educational resources, access to capital, and mentorship to help users find financial independence.

"When I created Equiliberty, I envisioned a world where everybody has access to mentors," said Yates in a press release. "I know firsthand the importance of having a supportive network and community dedicated to your success." Click here to read more.

Ryan Sitton joins the Houston Innovators Podcast to discuss his career in data and reliability. Photo courtesy of Ryan Sitton

This Houston innovator is using data to power industrial reliability and sustainability

HOUSTON INNOVATORS PODCAST EPISODE 92

Ryan Sitton has had a varied career so far. Formerly working in oil and gas, he started his own company in 2006 to help companies to better utilize their data. Now, still leading Houston-based Pinnacle as CEO, Sitton works with the world's largest companies to solve their problems with data. He also served as Texas Railroad Commissioner and has written two books about decision-making and leadership.

Sitton joined the Houston Innovators Podcast to discuss how, despite the multiple hats he wears, at the core of his passion is using data to drive better decision making to drive more sustainable and reliable operations.

"I was basically doing data analytics in the mid 2000s before it was sexy. I was pulling together data in chemical plants and refineries and trying to predict how these plants would behave with the data I had," Sitton says. "I realized early on how there was so much opportunity here — but we don't have the technologies or the methodology to do it."

But over the years, the technology has caught up and now Sitton is able to provide clients with even more data-driven solutions.

"We go into the biggest companies of the world that are trying to have more reliability at the same time as lowering cost," Sitton explains. "We build models that pull together literally millions of pieces of data and we do a combination of engineering analysis and data analysis and data science to give them better predictions — better ways to run their facilities so that they are more sustainable and more profitable."

Sitton's two books — Crucial Decisions, which is out now, and the Myth of Status, which is coming later this year — also center around decision making and leadership.

He shares more about his time at the Texas Railroad Commision and shares how COVID-19 affected business — as well as shares his advice for startups tapping into data-driven solutions — on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Ryan Sitton's new book, "Crucial Decisions," touches on an array of topics and how data is the key to making the positive and impactful decisions. Photo via Getty Images

Houston energy expert on how big data yields more reliable results

Guest column

Abraham Maslow's hierarchy of need tells us that at our core, humans crave safety and sustenance. When you turn on the light each morning while getting ready for work, or when you check your bank account and see your paycheck arrived on schedule, we expect every aspect of our daily lives to work.

In today's world, we often take these things for granted, until reliability is threatened. Our dependency is revealed in the frenzy over a potential toilet paper shortage and in the panic buying of gasoline in a hurricane. When things in society are consistent, economies thrive. However, when you introduce fear and uncertainty, things begin to spiral. It is in these times that the decisions we make can have the biggest impact on the world around us.

The link between impactful decisions and reliability has brought our society to a pivotal moment in history. We have created a society so reliable and developed that even during the coronavirus lockdown, the basic needs of Americans could be met with only 25 percent of our workforce actively working. By increasing productivity using machines and systems, we have been able to improve our overall quality of life, but not without a price. As a result of such high improvement, we as a society have come to not only expect, but demand, reliability at all times.

When dependability waivers and anxiety rises, those in key decision-making positions are faced with unprecedented situations. Due to distress and a lack of understanding of certain situations, those in decision making positions are often times forced to make decisions based on rapid response and emotion. Because of this, consistency and reliability suffer.

A prime example of an emotional response is the coronavirus shutdown that occurred earlier this year. As a response to the growing fear and panic over the virus, major portions of our economy were shut down; schools were closed; and citizens were confined to their homes.

What followed was the bankruptcy of thousands of businesses, an unprecedented wave of fear throughout society and a disruption to the consistency of our daily lives. We have yet to know what lasting impacts this decision will have on our future economy or livelihood, but we now understand that rapid decision making is often met with long-term consequences.

While there will continue to be disagreements on all sides regarding the handling of the shutdown, what is undisputable is that we as a society have gained an opportunity to learn. We now have the unique advantage of using data in ways that has never been used before in order to make consistently better decisions, allowing us the opportunity to perform at levels we have never thought possible.

Whether it be data advancements in sports (think Billy Beane and the Oakland Athletics), or the progression of technology (continuous iPhone updates), we are able to study the improvements of data on society in order to make more reliable decisions. With more powerful data analytics and innovations in data sciences, we are able to positively impact the most vital components of our society in order to make decisions that will drive evolution and reliability.

As the world continues to progress, the decisions we are forced to make have become more complex. With each complicated decision comes the potential for lasting positive or negative impact on society. In shifting from emotional, rapid reactions towards more data and quantitative focused methods, we have the unique and unprecedented opportunity to make our world a more reliable, stable and creative place.

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Ryan Sitton is the founder of Pinnacle and the author of "Crucial Decisions."

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”
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