The Welch Foundation has announced a $100 million gift to Rice University to establish The Welch Institute focused on materials science. Photo courtesy of Rice

A private foundation that funds chemical research within the state of Texas is dedicating funds to a new venture — an institute focused on advanced materials at Rice University.

The Welch Foundation announced today a $100 million gift to Rice University to establish The Welch Institute. The institute will foster the study of matter, the design and discovery of new materials, and nanotechnology, and it will be led by an independent board of directors and scientific advisory board.

"The Welch Institute will focus on the development of advanced materials for the good of society and to advance the vision of Robert A. Welch, who believed in basic chemical research as a powerful force for transformative breakthroughs and improving the quality of life," says Welch Foundation Chair and Director Carin Barth in a news release. "It will bring together top minds across all disciplines to catalyze innovation and center leadership in the field right here in the Houston area."

Material science has an impact across industries — from energy, water, space, telecommunications, manufacturing, transportation, and more.

"Innovation is the foundation of progress. More than ever, the discovery of new knowledge is in turn the precursor of innovation. That is why universities and the work we do are key components of the innovation ecosystem," said Rice University President David Leebron at the press conference. "We expect the Welch Institute to serve the needs of all mankind, but we also expect it will secure a stronger future for the people of Houston."

The institute has a huge opportunity to lead the way in material science in the United States — as most of the current research and innovation within this field is happening on foreign land.

"While [material science] is fundamental to every conceivable aspect of our lives, the United States may be falling behind in terms of advancement in this field," says Gina Luna, board member of The Welch Foundation and acting president of The Welch Institute, at the press conference. "Of the top 10 material science institutes in the world today, not one of them is in the U.S. We believe the Welch Institute can change that."

Luna adds that the organization will bring together experts together in Houston, "where we just know how to get things done," she adds.

Rice is an ideal home for the initiative, says Pulickel M. Ajayan, chair of Rice's department of materials science and nanoengineering, and Houston stands to benefit from the program as well.

"This new institute will serve as an international hub for materials research, so that people from all around the world can come here and spend time and see Houston and Rice as a destination for materials research," he adds.The Welch Foundation has granted over $1 billion in funds and has endowed 48 chairs at 21 Texas universities, says Peter Dervan, chairman of the Scientific Advisory Board of The Welch Foundation and Bren Professor of Chemistry at the California Institute of Technology.

"We want to develop the Institute while maintaining all of our legacy grant programs and awards, which have served Texas scientists so well over the years," he adds,

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Houston digital health platform Koda lands strategic investment

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Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

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Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”