It's time to vote for Houston's Startup of the Year. Graphic via Gow Media

We're just two weeks away from the 2025 Houston Innovation Awards, and while our expert panel of judges will determine the winners in most categories, one award is up to you.

Voting is now open for our people's choice award: 2025 Startup of the Year. Six exceptional finalists are in the running for the title, and your votes will determine the winner.

From rugged humanoid robots to next-generation sustainable materials, each of these startups is making an impact on the innovation ecosystem in Houston — and beyond.

Read about our Startup of the Year finalists and their missions below, then cast your vote. You can vote once per day through November 12, so make your voice heard.

The winner, along with winners in all other categories, will be revealed live at our event on November 13 at Greentown Labs. Tickets to the 2025 Houston Innovation Awards are available now — get yours today.

Eclipse Energy

Eclipse Energy, previously known as Gold H2, is a climatetech startup converting end-of-life oil fields into low-cost, sustainable hydrogen sources. The company completed its first field trial this summer, which demonstrated subsurface bio-stimulated hydrogen production. Eclipse Energy says Its technology could yield up to 250 billion kilograms of low-carbon hydrogen.

FlowCare

FlowCare is developing a period health platform that integrates smart dispensers, education, and healthcare into one system to make free, high-quality, organic period products more accessible. FlowCare is live at prominent Houston venues, including Discovery Green, Texas Medical Center, The Ion, and, most recently, Space Center Houston, helping make Houston a “period positivity” city.

MyoStep

MyoStep is a next-generation, lightweight, soft exoskeleton developed at University of Houston for children with cerebral palsy. The soft skeleton aims to address motor impairments that impact their ability to participate in physical activities, self-care, and academics, via an affordable, child-friendly solution that empowers mobility and independence.

Persona AI

Persona AI is a humanoid robotics startup that is creating rugged, autonomous robots for skilled, heavy industry work for various "4D" (dull, dirty, dangerous, and declining) jobs. In May, the company announced a memorandum of understanding with HD Korea Shipbuilding & Offshore Engineering, HD Hyundai Robotic, and Vazil Company to create and deploy humanoid robots for complex welding tasks in shipyards. The project will deliver prototype humanoids by the end of 2026.

Rheom Materials

Rheom Materials is a next-generation startup developing biobased materials for a more sustainable future. Its two flagship offerings are Shorai, a sustainable leather alternative that is usable for apparel, accessories, car interiors, and more, and Benree, an alternative to plastic without the carbon footprint.

Solidec

Solidec is a chemical manufacturing company developing autonomous generators that extract molecules from water and air and convert them into pure chemicals and fuels that are free of carbon emissions. The technology eliminates the need for transport, storage, and permitting.

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Calling all Houstonians — help InnovationMap decide on this year's People's Choice: Startup of the Year winner. Graphic via Gow Media

People's Choice: Pick your startup of the year for the 2024 Houston Innovation Awards

you decide

It's firmly voting season in Houston, and in addition to deciding the nation's next political leaders, the local innovation ecosystem is being called to weigh in on one category for the Houston Innovation Awards.

This year's People's Choice: Startup of the Year voting is officially open online. Read about each company below, then click here to cast your vote. You may vote once per day up until Nov. 8 when the portal closes. The winner will be named at the Nov. 14 event — click here to secure your ticket to see who wins in this and the other dozen categories.

Corrolytics

Founded by CEO Anwar Sadek, this minority-owned startup uses its patented electrochemical technology to detect and monitor corrosion. Unlike others in the market, Corrolytics allows for on-site, real-time, accurate detection of corrosion, helping to safeguard industrial assets and prolong their lifespans.

Last month, Corrolytics, which is also a finalist in the Minority-Founded Business category, was named among the most promising energy tech startups at the Rice Alliance for Technology and Entrepreneurship's Energy Tech Venture Forum and won the People's Choice Award. It was part of the Rice Alliance Clean Energy Accelerator earlier this year.

What significant milestone(s) has your company reached this year?

We launched our comprehensive in-lab services in Q4 of 2023, generating $100,000 in revenue. By 2024, we tripled our revenue, confirming our early product-market fit while serving four major customers in the energy sector. With the ruggedization and scalable design of our test kit now complete, we’re set to begin field trials in the next quarter. Additionally, Corrolytics has secured a Joint Development Agreement with a leading oil and gas service provider, extending our reach across the global energy market.

What advice do you wish you could tell yourself before you started your company?

Embrace the challenges early on, as they are invaluable learning opportunities. Focus on building a strong network, especially with mentors and industry leaders who can guide you through the unknowns. Lastly, be prepared for the unexpected, stay adaptable and never underestimate the importance of a clear mission that inspires both your team and your customers.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

Houston is the energy capital of the world, providing unparalleled access to major industry players, talent and resources. The city's strong focus on innovation and its thriving clean energy ecosystem has been a perfect fit for Corrolytics. Growing the company here has been an amazing experience—Houston’s vibrant startup community, world-class accelerators like the Rice Alliance, and its strategic location have accelerated our growth and opened doors to invaluable partnerships. Houston truly offers the ideal environment for scaling a cleantech startup like ours and advancing the future of sustainable energy.

FlowCare

FlowCare is focused on addressing menstrual inequity by providing flagship dispensers stocked with free, 100 percent organic pads and tampons for schools and businesses, while raising awareness about the issues that impacks millions.

The startup was founded in January and is led by Founder and CEO Tanu Jain.

What significant milestone(s) has your company reached this year?

Here’s a summary of the significant milestones FlowCare has reached this year:

  • Building a supportive community: We’ve established a vibrant community of FlowCare cheerleaders and advisors who are passionate about our mission.
  • Newsletter Success: Our newsletter, launched just two months ago, now reaches 2,000 people each month with an impressive 50 percent to 60 percent open rate. We’ve also been moved by the personal stories of period struggles shared by our readers.
  • Competition Achievements: We secured fourth place in the Houston Community College Business Plan Competition, winning $1,000 and raising awareness about period product accessibility. FlowCare also earned a top four finish out of 200 participants in the TiE Dallas Global Pitch Competition.
  • Successful Pilot at ION: We’ve commenced a paid pilot with ION, receiving heartfelt text messages from women expressing how FlowCare has positively impacted their day and alleviated embarrassment by providing period products in restrooms."

What advice do you wish you could tell yourself before you started your company?

Expect the journey to be challenging and more time-consuming than anticipated. You’ll face financial struggles and setbacks, but remember to stay patient and resilient. Embrace the journey and find joy in the small victories along the way. Build a network of supportive individuals who believe in your mission and can help you navigate the tough times. You’ll experience self-doubt and imposter syndrome, but remember, even high-profile leaders experience these feelings. Stay focused on your mission and trust in your ability to make a difference.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

I chose Houston for FlowCare’s headquarters because it’s home to me—having grown up here, it felt natural to build my company in a place I know and love. My experience growing the company here has been incredibly positive. Houston boasts a strong and supportive community with a robust network of individuals who are always willing to help. As an entrepreneur, having access to people who are willing to spend time with you, offer guidance, and introduce you to the right connections is invaluable. The local support has been a key factor in keeping us going towards the mission of period equity.

InnoVent Renewables

InnoVent Renewables is a circular economy business that has developed a proprietary net-zero process that converts waste tires, plastics, and biomass into fuels and chemicals. It estimates that it will reduce emissions by 80 million pounds when its production facility is operating.

InnoVent was founded by chemical-engineer-turned-CEO Vibhu Sharma in 2023. It has plans for aggressive growth across North America and Latin America.

What significant milestone(s) has your company reached this year?

We started our business in July 2023, raised a "friends and family" round, which was oversubscribed, and we carry no debt. We went from concept to the commissioning stage in 14 months and will start full commercial operations in Q4 2024.

What advice do you wish you could tell yourself before you started your company?

Always raise more cash than you think you will need. We raised a friends and family round and then had to tap that network again to get some additional funds to account for some add-ons and escalations.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

Houston is a remarkably affordable city with exceptional talent and expertise in engineering, design, renewables, and oil and gas processes. In addition, we were able to tap an excellent and experienced advisory board that has been guiding us. Houston is well connected with the rest of the world, as well as easy access to Monterrey, Mexico, where our tire facility is located.

MendIt

MendIt Inc. was founded in 2019 to help quickly and easily connect users with small businesses and non-profits that can mend and repair clothing sustainably.

It is led by CEO and founder Kaitlyn Allen and was a member of the gBETA Houston accelerator in 2023.

What significant milestone(s) has your company reached this year?

We are finally in the feasibility phase of our (stealth) B2B offering for brands and are excited that the initial results are positive and are pointing to scalability. We are currently in the process of contracting to provide our solution for two initial B2B customers.

What advice do you wish you could tell yourself before you started your company?

Seek product-market fit from the beginning (rather than product-problem fit), and don’t invest so much before that is demonstrated.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

We founded MendIt in Houston because it is our hometown and where we lived. It’s been interesting growing a non-energy-related company because so many of the resources are focused on that sector, and at the same time we get to stand out as the only “tech” startup focused on fashion and textile sustainability.

Passport Journeys

Passport Journeys is a teletherapy app that's specifically designed for mother-daughter pairs. The app launched on Mother's Day 2023 and provides users with personalized therapies, journal opportunities, interactive worksheets and intentional bonding activities.

The company is led by founder and CEO Lacey Tezino.

What significant milestone(s) has your company reached this year?

This year, we’ve achieved several significant milestones: We filed for a trademark to protect our brand, applied for our first NIH SBIR grant to secure funding for our innovative teletherapy app, and launched a nonprofit arm to provide free therapy to those in need, demonstrating our commitment to both innovation and community support.

What advice do you wish you could tell yourself before you started your company?

I would advise myself to secure funding and the sustainability plan for the first five years before leaving the big corporate job.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

We chose Houston for our company’s headquarters due to its vibrant and diverse community, robust health care and tech sectors, and supportive entrepreneurial ecosystem. Growing our company here has been a rewarding experience, marked by strong local partnerships, access to a large talent pool, and a dynamic business environment that fosters innovation and collaboration. The city’s emphasis on healthcare and technology aligns well with our mission, providing a solid foundation for our growth and impact.

TrueLeap

Ed-tech startup TrueLeap Inc. aims to address the global education gap by providing affordable, scalable digital tools to educators in emerging markets through its e-learning platform.

Founded in 2022, it raised $610,000 in a pre-seed round earlier this year, which was over its target of $500,000. It's led by co-founders Sandip Bordoloi, who serves as CEO, and Sunny Zhang, the company's Chief Evangelist. Dario Calogero, founder and CEO of Maya Investments Limited, which led the round, was recently named to the company's board of directors.

True Leap is being developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology, of which Zhang is a founding partner. It serves educators in schools in the United States, India, the Democratic Republic of Congo and other countries.

What significant milestone(s) has your company reached this year?

Advancing our mission to make education accessible to underserved communities worldwide, we have reached the following milestones:

1. New country entry into Ghana by partnering with International Business and Opportunity Network (IBON)
2. Expanded implementation in the DRC by partnering with the Catholic School Association
3. New product launch enabled global educators and institutions to create and distribute high-quality content to prepare global talents for success.

What advice do you wish you could tell yourself before you started your company?

Just do it.

Why did you choose Houston for your company's headquarters and how has your experience been growing a company here?

We chose Houston for its diversity and international connections, which align with our mission to expand access to education worldwide. The city's supportive startup scene, access to top talent, and thriving innovation ecosystem have made it an ideal place to grow TrueLeap.

Pick your 2024 Houston Startup of the Year.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”