The Texas Medical Center is buzzing with recent innovation news, from Texas A&M University naming its buildings, Houston Methodist is introducing a new technology, and more. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, Deloitte is looking for tech companies to honor, a few Houston innovators have fresh funds, buildings rising in the Texas Medical Center now have names, and more.

Texas A&M names buildings in Innovation Plaza

Texas A&M University has named the buildings that will be a part of its Innovation Plaza. Photo courtesy of Texas A&M University System

The Texas A&M University System has revealed the names of the three buildings in the Texas A&M Innovation Plaza rising near the Texas Medical Center: Discovery Tower, Life Tower, and Horizon Tower.

Discovery Tower is the future home of A&M's EnMed program and is currently being renovated from an 18-story office building. Life Tower, which is expected to deliver in June 2022, is a 19-story, 714-bed student housing tower for Texas A&M medical students and Prairie View A&M University nursing students. Lastly, the Horizon Tower will be a 17-story, 485,000 square-foot integrated building that will feature a 13-story parking structure at the bottom.

SecurityGate closes series A

Ted Gutierrez, CEO of SecurityGate, announced the closing of his company's series A. Courtesy of Security Gate

SecurityGate.io, a software-as-a-service cybersecurity startup based in Houston, has closed its series A fundraising round. Houston Ventures led the capital raise. The amount raised has not been disclosed.

"It was very attractive to us how tightly tuned SecurityGate.io is to the needs of their customers," says Chip Davis, managing partner at Houston Ventures, in a news release. "Successful enterprise software companies generally know they are instruments of change for their customers."

Davis says the feedback from SecurityGate's customers was what sealed the deal.

"Digital transformation is no easy task in highly dynamic environments, especially when the risk of cyberattacks keeps rising daily. We're excited to partner with Houston Ventures who sees this market growing, and our clients that see our vision of the future," says Ted Gutierrez, CEO of SecurityGate, in the release.

Well Health launches at Houston Methodist

Thanks to tech from the West Coast, a Houston hospital has optimized virtual visits. Courtesy of Methodist Hospital/Facebook

Through a partnership with California-based WELL Health Houston Methodist was able up the ante on virtual visits during the pandemic. According to a news release, WELL enabled Houston Methodist to deliver over 260,000 text messages to patients Houston Methodist. The messages educated them about virtual care, schedule visits, and more.

"The ability to communicate back and forth, assuring patients that we are here for them both virtually and in-person is crucial as we continue to safely provide care in the midst of this pandemic," says Tesha Montgomery, vice president of operations and patient access at Houston Methodist, in the release.

Houston podcast network raises over $1 million

A podcast network with Houston ties has raised a seed round. Pexels

Lemonada Media, a podcast network with Houston roots that launched in September, has raised $1.38 million in a seed funding round led by Blue Collective, an early-stage venture capital firm. The fresh funds will allow for strategic growth for the two co-founders, Jessica Cordova Kramer, CEO, and Houstonian Stephanie Wittels Wachs, chief creative officer. Lemonada also plans to hire several positions including vice presidents across finance, production, and marketing.

"We are slated to be a content and talent incubator, spinning out new audio concepts and hit series that present humanity, unfiltered," says Wittels Wachs in a news release. "Now more than ever, people are hungry for content that addresses their lived experience, those that are mundane, and those that may be painful and isolating. Because our company was built off a mountain of personal grief and loss, Lemonada is well-situated to cut through the noise, create beautiful works of art, and make people laugh and feel less alone along the way."

Deloitte is looking for tech companies for annual competition

For the 26th year, Deloitte is looking for cutting edge tech companies. Photo courtesy of Deloitte

Deloitte has opened applications for its 2020 Technology Fast 500. The application is available online and closes July 17. To be eligible for the award, the startup must be in business for a minimum of four years, have its headquarters in North America, have fiscal year 2016 operating revenues of at least $50,000, a fiscal year 2019 operating revenues of at least $5 million USD with a growth rate of 75 percent or greater, and own proprietary intellectual property or proprietary technology which must be sold to customers in products or services that contribute to a majority of the company's operating revenues, according to the contest's rules.

Companies should also fall within one of the following industry categories: biotechnology/pharmaceutical, communications/networking, digital content/media/entertainment, electronic devices/hardware, energy tech, medical devices, semiconductor, or software/SaaS.

Lazarus 3D delivers PPE to Haiti

A few Houston innovators have helped get Haitians critical PPE. Photo courtesy of Orolait

A few Houston innovators have helped connect health care workers in Haiti to some PPE. Ana Rojas Bastidas, founder of Orolait, and Jacques and Smriti Agrawal Zaneveld of Lazarus 3D, teamed up to ship over 1,000 pieces of PPE to United States Foundation for the Children of Haiti which supported orphanages, schools, and a hospital called Hopital Espoir.

In the middle of April, Bastidas saw the organization's need for PPE and saw how Lazarus 3D was creating materials. The group in Haiti received the supplies by the beginning of June.

"I'm really proud of the collaboration between myself and the Lazarus 3D team," Bastidas says. "Smriti and Jacques are absolute gems and while our businesses are completely separate, we found a common problem we both had the resources to tackle."

CryptoEQ begins offering consulting packages

Need custom cryptocurrency support? CryptoEQ is here to help. Courtesy of CryptoEQ

A cryptocurrency startup based in Houston has expanded its service to include custom-consulting packages.

"With our personalized packages, gain the market insights you need to refine your cryptocurrency investing and trading strategies," writes Spencer Randall, co-founder and principal of CryptoEQ.

The packages come at three levels: the enthusiast, the professional, and the expert. The individualized support begins at $499, and more information can be requested from the startup by emailing team@cryptoeq.io.

This week's set of who's who include a startup founder trying to change the world, a passionate PhD with a story of failure to tell, and a biomedical engineer enhancing health tech in Houston. Courtesy photos

3 Houston female innovators to know this week

who's who

Another set of female innovation leaders are making headlines as we move into another week of innovators to know.

This week's set of who's who include a startup founder trying to change the world, a passionate PhD with a story of failure to tell, and a biomedical engineer enhancing health tech in Houston.

Ana Carolina Rojas Bastidas, founder of Orolait

orolait

A Houston mom is working hard on her startup so that next summer, breastfeeding moms can swim in style and worry free. Courtesy of Orolait

On the surface, it may seem that Houston mom Ana Carolina Rojas Bastidas has a passion for fashion, as she's created and is fundraising for a new-mom specific line of swimwear. But really, she's on a mission to give breastfeeding women back their dignity with her startup, Orolait.

"I decided to build this company to challenge and change the way we depict one's breastfeeding journey," Bastidas says on the website. "I stand on the pillars of advocacy, education, and inclusion. You will see the sizing and advertising featuring all shapes, sizes, and shades because each of us is so different and that is what makes us so incredible and I am going to unapologetically celebrate that in the most ethical way I know how." Read the story.

Brittany Barreto, venture associate at Capital Factory

Brittany Barreto

Brittany Barreto founded the first nationwide DNA-based dating app, and she shares her story of its unexpected, and unavoidable, downfall. Photo courtesy of Pheramor

After dedicating three long years to her startup that began as an idea in college, Brittney Barreto is saying goodbye to Pheramor. Barreto explains how her DNA-based dating app got pulled from the Apple app store following policy changes, and how it left her with no choice but to shutter the operation.

Now, Barreto has big plans for funding femtech, and is learning a lot in her new role at Capital Factory. She's already able to do more for other founders and create a bigger impact.

"I realized that over the past two years, I had already been ad hoc coaching and mentoring founders and loving it," Barreto says. "Now, I was doing it and getting paid for it, on a bigger scale, and with more resources. I knew it was the journey I wanted to continue down." Read the full story.

Emily Reiser, senior manager of innovation community engagement at TMC

Emily Reiser

From robots and accelerator programs to her favorite health tech startups, Emily Reiser of the TMC Innovation Institute joins the Houston Innovators Podcast. Photo courtesy of Emily Reiser

Emily Reiser has known for most of her life that she's wanted to work in health tech — in some capacity. On the Houston Innovators Podcast, she explains how she combined her early interest in health care with her affinity with engineering inspired by her parents.

Now, she continues to check both those boxes at the Texas Medical Center's Innovation Institute, which has evolved a ton over the past year.

"In 2019, we had a lot of big changes around our team and our leadership," she says on the podcast. "That enabled us to take a bigger breath and a bigger pause to say, 'How are we really doing? And how could we be doing better?'" Read the full story and stream the podcast.

A Houston mom is working hard on her startup so that next summer, breastfeeding moms can swim in style and worry free. Courtesy of Orolait

New mom-designed swimwear line makes a splash in Houston

mommy made

Houston mom Ana Carolina Rojas Bastidas feels there's been an oversight in the fashion industry when it comes to women who are in the breastfeeding stage of motherhood. With her new swimwear line, she hopes to spark a movement for women's fashion.

Bastidas, founder and CEO of Orolait, launched the swimwear line in September 2018 specifically for breastfeeding individuals. Orolait, which floats the tagline "by a mama for mamas," aims to give breastfeeding individuals back the dignity they deserve with bathing suit options.

"I decided to build this company to challenge and change the way we depict one's breastfeeding journey," Bastidas says on the website. "I stand on the pillars of advocacy, education, and inclusion. You will see the sizing and advertising featuring all shapes, sizes, and shades because each of us is so different and that is what makes us so incredible and I am going to unapologetically celebrate that in the most ethical way I know how."

Bastidas, originally from Bogota, Colombia, has been blogging about postpartum body positivity on her platform PowerToPrevail since 2015, sharing her personal journey with her children.

"I was spending a lot of time by the pool and water parks with my two older children," her website states. "I had a big fear of public breastfeeding, but I had a life to live and memories to make with my kids."

Orolait currently offers four different types of bathing suits, each designed to make breastfeeding easier. The suits range from $36 per piece to $72 for a full suit. The suits are designed manufactured by MIYH Design Services, a local business owned by adjunct Art Institute of Houston professor David Dang.

Bastidas tells InnovationMap that she noticed the need for specifically designed suits after experiencing discomfort herself, explaining that traditional suits were not accommodating for swollen milk ducts with the cut and wiring. Bastidas surveyed mothers across all walks of life to see what they struggled with when finding a bathing suit and found that the list was endless. She tells InnovationMap that they got 100 responses in three days.

Her survey found that moms worried about body image, functionality, confidence, feeling fashionable, and comfort, all when looking for a bikini. It became clear to Bastidas that the current market was not working for moms and causing even more stress.

"Our goal is not to be modest," says Bastidas. "I don't believe in modesty when it comes to breastfeeding, but I do believe that people are at different levels and we need to meet them where they are at."

This past November, Orolait launched their first-ever equity crowdfunding campaign through LetsLaunch, a platform based out of Houston, with a goal of raising $250,000. The company reached 10 percent of its goal within its first few days of going life.

"Our goal is to help women who decide that breastfeeding is a journey that they would like to take, to be able to take that journey," says Bastidas. "There are so many obstacles that are already in our way biologically, that to have a lack of product be the reason why you become so discouraged is unacceptable."

Bastidas tells InnovationMap that her goal for the company is to eventually expand offerings in addition to bathing suits and move into brick and mortar retail spaces. She hopes that Orolait will be a representation of all varieties of breastfeeding journeys.

"We want to make sure we represent those moms who are never represented," says Bastidas.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”