Houston investors, mentors name 9 most promising energy startups at Rice Alliance event

best of the rest

Here are the most promising energy tech startups in the market today. Natalie Harms/InnovationMap

This week, 39 energy startup companies from all over the world pitched in Houston — and nine were recognized as being the most promising of the batch.

The Rice Alliance for Technology and Entrepreneurship returned its Offshore Technology Conference pitch event to its in-person capacity and host the annual event at the Ion Houston for the first time. The event featured three-minute pitches from the companies, and a select group of corporate and venture investors decided on the top nine to honor.

"We asked investors and corporates to look at the companies here today and help us determine the companies most promising — based on those that have an innovative technology that is solving a large problem, has customers willing to pay for it, and has the right team to build and grow their company," Brad Burke, managing director of the Rice Alliance says to the crowd at the event on May 3.

Here's which energy tech companies stood out to investors.

EarthEn

EarthEn, a Chandler, Arizona-based company, is a grid-scale energy storage solution. The technology can provide short-term — 6 to 8 hours — and long-term — over 100 hours — storage. The EarthEn pods provide a cheaper alternative and are built using 3D printing.

Echogen Power Systems

Based in Akron, Ohio, Echogen Power Systems has created a technology that captures heat that would otherwise be lost and converts it to a useable power source. The solution allows for any customer that operates at significant levels of heat to have a cost-effective energy option.

FuelX Innovation

Based in Aiken, South Carolina, FuelX Innovation is manufacturing solid-state hydrogen products and power systems, impacting mobile hydrogen fuel cell-powered applications. The company is focused on producing the lowest cost Alane, or aluminum hydride, for the fuel cell.

Lillianah Technologies

Lillianah Technologies, based in the Houston area in Spring, uses algae to remove carbon dioxide from the atmosphere. The company sells carbon offsets to corporations.

oPRO.ai

​oPRO.ai — which is based in Los Altos, California — is providing its customers with deep learning optimization software for process and responsible operations for oil and gas, petrochemical, chemicals, and metal industries.

Proteum Energy

Phoenix, Arizona-based Proteum Energy provides its customers low-cost, clean hydrogen by reforming renewable ethanol into renewable hydrogen.

Sync Power Solutions

Embracing a clean sheet approach, Sync Power Solutions, based in Abilene, Texas, created a solution involving a redesign of electric motors and generators to increase energy efficiency, save on costs, and more.

Utility Global

Houston-based Utility Global is using high temperature electrolysis without the use of electricity to produce hydrogen from waste gases.

ZL Innovations

Based in Portland, Oregon, ZL Innovations is focused on eliminating greenhouse gas emissions from failed industrial valves. The company's solution is a magnetic actuation assembly that can be better sealed to prevent emissions.

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Texas universities develop innovative open-source platform for cell analysis

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What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.

Texas ranks among the 5 best states to start a business in 2025

Best for Biz

As one of the largest states in the U.S., it's no surprise Texas is big on business and entrepreneurship. Now the state is earning new praise among WalletHub's 2025 list of "Best & Worst States to Start a Business."

The Lone Star State claimed the No. 4 spot in the report's rankings, proving that Texas is in a much better business shape than it was last year when it earned No. 8 in WalletHub's annual report.

The study compared all 50 states across 25 metrics to determine the best places to start, grow, and find success with a new business. Factors that were considered include the number of startups per capita, job growth rates, financing accessibility measures, labor costs and corporate tax rates.

The three states to outperform Texas in the 2025 report are Florida (No. 1), Georgia (No. 2), and Utah (No. 3). Idaho rounded out the top five.

Across the study's three main categories, Texas performed the best in the "business environment" category, earning No. 1 nationally. This section compares the states based on five-year business survival rates, average business revenues growth and more.

Texas ranked No. 12 in the nationwide comparison of "access to resources" – which covers working age population growth, venture investment amounts per capita and other means – and earned a fair No. 34 in the report's "business costs" ranking.

But Texas can still do better with its business friendliness to reclaim a top-three overall ranking, which the state last earned in 2023.

WalletHub analyst Chip Lupo said in the report that it is imperative for potential new business owners to establish their enterprise in a place that can maximize their ability to succeed.

"Around half of all new businesses don’t survive five years, so the idea of becoming a business owner can be daunting, especially with the current high cost of living," Lupo said. "The best states have low corporate tax rates, strong economies, an abundance of reliable workers, easy access to financing and affordable real estate. On top of that, you’ll need to make sure you start in a place with an engaged customer base, if you’re operating locally."

Houston has also proven to be at the top of the destination list for entrepreneurs who are looking for their next venture.

The top 10 best states to start a new business in 2025 are:

  • No. 1 – Florida
  • No. 2 – Georgia
  • No. 3 – Utah
  • No. 4 – Texas
  • No. 5 – Idaho
  • No. 6 – Oklahoma
  • No. 7 – Nevada
  • No. 8 – Colorado
  • No. 9 – Arizona
  • No. 10 – Kentucky
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This story originally appeared on our sister site, CultureMap.

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