Everest will sell products from more than 1,000 U.S. manufacturers. Photo courtesy of Everest

Houston businessman Bill Voss has forever found his zen through his lifelong passion for the great outdoors, but there’s one aspect that was making him positively furious: the shopping.

Burned out with driving to brick-and-mortar stores, standing in long lines, and dealing with dreaded returns, Voss turned his necessity into invention and launched Everest.com, a new shopping/lifestyle marketplace and community platform that links active-minded customers to more than 1,000 U.S.-based merchants and retailers.

By utilizing what it describes as “state of the art” artificial intelligence, the company aims to create the largest marketplace on earth for the outdoor recreation community, covering activities such as hiking, camping, biking, rock climbing, winter sports, water sports, team sports, fishing, hunting, kayaking, rafting, and road and trail running.

Voss’ timing is sound: Current industry estimates suggest consumers spend $700 billion in outdoor recreation, with less than 20 percent of those sales transacted online. Towards that end, Voss plans to increase his sellers to 10,000 by 2023.

Everest members can also enjoy perks through a program dubbed Caliber, which provides its members with several exclusive benefits including free shipping, advance sales, travel benefits, big discounts on gear, and — a plus these days — discounts on fuel. Voss notes that the site’s core values are pushing U.S.-made products and giving back; Everest will have nonprofit and conservation partners.

CultureMap caught up with the active Voss on the heels of his Everest launch.

CultureMap: Congratulations on the launch. Essentially, have you created an Amazon for the outdoors crowd — but with a sense of community, too?

Bill Voss: We started Everest.com to create the first online marketplace with the sole focus of offering outdoor enthusiasts retail goods for purchase from merchants across the country who offer domestically made goods.

In our experience, people who love the outdoors also appreciate the concept of community. At Everest, we want to bolster that community by giving local businesses a wider sales reach, contributing to local and national charitable organizations, and asking everyone in our community to share the story of their “Everest.”

We’re taking a fairly segmented market and bringing it together into one community-focused ecosystem. We call that ecosystem Everest.


CM: What Houston spots have most inspired you? And have you visited Everest yet?

BV: I’m a fisherman at heart. I have been fishing the Gulf of Mexico since I could hold a fishing rod. There is nothing I’d rather do than spend a whole day on the water casting, trolling, or remembering many epic fights reeling in a big one.

So naturally, I love Galveston, Kemah, etc. and being so close to the Gulf is a huge reason why I love Houston. The city itself may be a major metropolitan area, but it is full of so many parks and recreation areas that are great to walk through when you need to escape the sounds of the city for a bit— which Houston really doesn’t get enough credit or exposure for.

Houston has an amazing outdoor community with so many choices to support it — it’s hard to pick just one activity that ranks number one.

I do have plans to visit Everest actually! I am arranging a trip with two brothers that have made it to the top more than anyone else and they assure me it will be an amazing trip.

CM: Clearly, you’re an avid outdoorsman. Is it correct to say that Everest was inspired by frustration and hassle of bouncing to other sites and stores?

BV: Exactly! I found myself doing just that and it’s infuriating. I’d be visiting multiple stores, going through multiple checkouts, and waiting on multiple boxes to arrive — and sometimes dealing with multiple return scenarios. So, I set out to fix it — for all of us.

I grew up fishing, spending hours on the water with my dad. To me that’s one of the best parts of any outdoor activity, the quality time spent with the people you love. I don’t think you get the same experience if you’re sitting around a tv screen together, and you certainly don’t get it if you’re spending hours on your computer trying to track down the perfect beginner fishing rod for your daughter. Time is precious, and the endless toil of gear compilation eats into those few available hours we have to spend together.

By aggregating thousands of outdoor brands and gear retailers and centralizing them into one marketplace, we’re allowing our users to hop on, find everything they need, and check out easily. We’re just getting started but, within the next two years, we hope to add even more sellers and products along with more community offerings.

Being out on the water showing my kids how to bait a hook or how to find a school of fish, those are the memories I hope they take with them. With Everest, it has been important to me to help make those kinds of experiences easily attainable for everyone and the people they love.

CM: Speaking of other stores, do you plan to go head-to-head with the REIs and Sun and Skis of the world? Or Amazon?

BV: I get this question all the time and I love it. As to the first two, definitely not. We’re a marketplace, we’re here to help companies like REI and Sun and Ski, who can participate as sellers and reach new customers.

The difference is that our members can pick up everything they need, from multiple retailers, in one cart, with one easy checkout option. Many of the big names already spotlight and sell products on Amazon — they can do the same with Everest. We are a community of like-minded outdoor loving enthusiasts that have been looking for a niche marketplace to serve all of us.

Think of what Chewy did in the pet industry — we are doing the same thing for those that love the outdoors. Amazon has to be everything to everybody. We don’t, and we don’t want to.

CM: Do you see Everest ever creating brick-and-mortar stores?

BV: Wonderful question. The beauty of Everest is we are still a young company with options to consider. But remember, one of the main tenets of Everest is supporting our sellers. We are not looking to get into a situation where we are competing directly with them.

However, we’d love to one day open a shop selling Everest sweatshirts and swag in downtown Houston. It would be so fulfilling to see the outdoor community wearing Everest branded clothing and putting Everest stickers on their gear in the future.

The bottom line is, we are sprinting as hard as we can in hopes of waking up one day as a true disruptor, household name, and eternal brand.

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This article originally ran on CultureMap.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”