The University of Houston has transformed its Energy Research Park into the Technology Bridge to better connect research-based startups to the market. Natalie Harms/InnovationMap

A few years ago, the University of Houston renamed its Energy Research Park to the Technology Bridge. They wanted to create a program and workspace for companies inside the university to enter into the Houston innovation ecosystem. Turns out, the program also created a bridge for innovative companies entering the Houston market.

Two companies announced that they will open operations in the Technology Bridge — the first Houston offices for both, according to a news release.

Chemicals company Oleon is a subsidiary of France-based Avril, a financial and industrial company. Before the UH location, Oleon's only United States operation was a sales office in South Carolina. The other company is California-based Saratech, an engineering, software, services, and 3D printer sales company. Saratech has offices across the country, including an Austin office. The Houston office will focus on 3D printing.

According to Tom Campbell, executive director of the UH Office of Technology Transfer and Innovation, choosing a university to open a new office in a new market makes a lot of sense. There's a ready-made network of professors and students ripe with talent for internships and new and developing research.

Saratech's senior vice president, Rick Murphy, agrees that the new office can be mutually beneficial to UH and his company. Saratech already has a relationship similar to this with the University of California-Irvine.

"We are looking at universities to help with that, so industry can start educating their engineers to take advantage of this technology," Murphy says in the release.

Oleon also has previous relationships with universities in Europe and Asia. The company, which specializes in natural chemistry — specifically using fats and oils in various applications from cosmetics to automotive, plans on sustaining a lot of growth in Houston. The move represents the first of many instances of growth in the market.

"It is baby steps here, but the U.S. is a huge market," Dave Jacobs, general manager of operations for Oleon Americas, says in the release. "About 50 percent of the oil and gas market is here."

The Technology Bridge houses 23 startups and has 30,000 square feet of incubator space and over 700,000 square feet of space suited for laboratories, pilot-scale facilities, and light manufacturing. The bridge sits on the former Schlumberger campus just south of UH.

To Campbell, the bridge adds its own niche of research and lab space to the Houston innovation ecosystem as a whole, and both these companies' new offices are on par with the greater goals of the bridge.

"It's about economic development," Campbell says in the release. "A strong innovation economy is a rising tide that floats all boats."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

---

This article first appeared on EnergyCapitalHTX.com.