Breaker19 is an Uber-like truck booking platform founded by two Houstonians. Photo via Getty Images

In a world where ”the customer is always right," two Houston founders have followed that rule right to their next venture.

Breaker19 — a groundbreaking mobile application built in late 2023 to be an efficient oilfield trucking and hotshot marketplace — was co-founded by Rodney Giles and Tyler Cherry. The native Houstonians also co-founded BidOut, a leading Oil & Gas procurement platform in 2021.

“About a year ago, one of our BidOut clients, a large operator, came to us and basically said that the biggest problem they have in the oil field is ordering trucks,” remembers Giles. “From there, they asked would we be willing to build something similar to Uber, but for oilfield logistics and trucking? So, we built Breaker19.”

After their customer presented a challenge, Giles and Cherry got to work. They envisioned the technical architecture almost immediately and assembled a team of software engineers to build an in-house application in less than a year.

“We launched Breaker19 in November 2023, and my goodness, it has taken off like crazy,” says Giles. “It is growing incredibly fast. We’re doing hundreds of truckloads a day now, all throughout West Texas, South Texas, North Dakota, really all over the U.S.”

Now, armed with such large publicly traded companies as British Petroleum, Breakout19 has a network of more than 1,500 trucks similar to transportation companies like Uber, where drivers make themselves available to be dispatched according to their health, safety and environmental requirements.

Breaker19 is doing so well, in fact, that it’s sped past Giles and Cherry’s original collaboration, BidOut.

“Breaker 19's probably, you know, growing ten times of where BidOut even was in its early days,” says Giles. “So, we'll always explore options that make sense for our shareholders. Fortunately, my co-founder and I have previous companies that we built and sold and have experience in scaling and have experiences in multiple departments, whether it be finance or sales or marketing or operations.

“So, currently, we do operate BidOut and Breaker19 separately, but they are, you know, through common operating structures. And, you know, we're able to maintain the scale and maintain the growth right now. And right now, the company is doing great financially and has cash flow positives. So, for us, you know, our goal is just to continue. I feel like we've kind of solved an archaic problem and did it in a really simple way, and it's working out pretty well.”

And it all started with a simple question from a customer — "Hey, can you guys come up with something like this?"

“It all came together just by listening to our customer’s needs,” says Giles. “And we always try to go into our clients and help them with a lot of what they do. But we always want to know about what their other pain points are. You know, there's still people, you know, that are operating with very archaic processes, very, you know, manual back-office processes. And our job is to speed them up with software. And so Breaker19 was able to do that.”

Practically speaking, Breaker19 is more than a software solution. It also closes the gap between qualified drivers and end clients by vetting participants for the platform in an efficient and pragmatic fashion.

“We have a very rigorous vetting process for the drivers,” Giles explains. “I mean, that's really what makes the oil and gas trucking industry so unique. Insurance requirements have to be significantly higher than most carriers. They have to go through very well-funded safety trainings where they are familiar with the oil field. And then number three, these drivers have to have personal protective equipment. They have to have flame-retardant clothing, they have to have slo-mo boots and they have to have hard hats.”

Procedure is important, but professionalism is equally important to Breaker19.

“You know, we do not allow the carrier to show up on a customer's locations in shorts and flip-flops or Crocs and, you know, be protected,” says Giles. “And so, for what we're dealing with is very mission critical, but also very, you know, very high-risk.

“For example, we are checking insurance statuses four times a day. If a carrier were to cancel their insurance, we're aware of it immediately because we want to make sure that we always have active insurance in place. So, we have a process that these carriers go through. Again, we've got over 1,500 of them now that are well-vetted and well-qualified.”

As Breaker19 continues to scale, Giles and Cherry hope their burgeoning app becomes the go-to ordering platform for the entire oil and gas industry for all of their trucking, hot shot and transportation needs.

“We're bringing on some significant, large enterprise clients right now that make up 10% of the U.S. market share for each customer,” says Giles “So I think when we start to compound those, I think we easily see the trajectory there as really being something that's taking off pretty fast. So, I think at the end of the day, we just hope to keep delivering a great experience for our clients, make their ordering process easy.”

With both BidOut and Breaker19 doing great financially, proud Klein Oak High School alums Giles and Cherry have purchased a steer to support Texas youth and agricultural causes. Additionally, moving forward, the duo pledges to give away a full steer each month to a customer of their Breaker19 platform.

"We are passionate about giving back to our community and nurturing the next generation of leaders in Texas," says Cherry. "Having personally experienced the transformative impact of FFA, we saw this initiative as a meaningful way to both support local agriculture and provide our clients with a taste of authentic Texas beef.”

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."