Rice Alliance names the 10 most promising startups at Houston's Offshore Technology Conference

Best of the rest

Startups from across the world pitched at the Rice Alliance Startup Roundup at the Offshore Technology Conference. Getty Images

Over 50 different startups from across the globe gathered at the Offshore Technology Conference for the fifth annual Rice Alliance Startup Roundup event. The full day of speed pitching and presentations, hosted by Rice Alliance Managing Director Brad Burke, took place at NRG Arena on Monday, May 6.

After interacting with all the various startups, the Rice Alliance's panel of experts voted on the 10 most promising startups. Half of the companies that were recognized are based in Houston — and even more have an office or some sort of operations in town. Here's which technologies the offshore oil and gas industry has its eye on.

Oliasoft AS

Oliasoft provides solutions for digitizing well planning operations. Photo via oliasoft.com

Oslo, Norway-based Oliasoft kicked off the presentations at OTC and walked away with an award 2.5 hours later. The cloud-based technology allows for enhanced well planning, casing and other drilling engineering processes.

Syzygy Plasmonics

Syzygy Plasmonics is a chemicals company in Houston lead by Trevor Best. Best presented his company's hydrogen as a fuel alternative technology. According to best, Syzegy's technology is a lower cost solution to gasoline that doesn't put out any chemical waste.

Toku Systems Inc.

Canadian IIoT company, Toku Systems Inc., has a inexpensive monitoring device. Photo via tokuindustry.com

When it comes to monitoring operations, it can be pricey and inaccurate. Edmonton, Alberta-based Toku Systems Inc. has designed a solution. Toku's device is durable and uses IIoT technology to allow for oil and gas companies to monitor their operations remotely.

Ingu Solutions

Ingu Solutions' Pipers technology might look small — but it's able to save a whole lot of cash for oil companies and prevent leaks. Photo via ingu.co

Another Canadian company, Ingu Solutions from Calgary, Alberta, took home an award from Rice. The company's pipeline detection technology can access pipes' conditions and prevent leaks and damage from causing major, costly events. Ingu's Pipers technology works off a subscription model, so clients have access to support and supplies with their monthly fees to the company.

LaserStream

LaserStream uses its imaging technology to track the wear and tear on pipes. Photo via laserstreamlp.com

Humble-based LaserStream provides laser-based scans of pipeline. The technology can evaluate damage and corrosion as well as calculate measurements of various equipment. The company has inspected over 350,000 feet of materials , including tubing, casing, drilling risers, production risers, and more, according to the website.

Ondaka

Ondaka's technology allows you to visualize your infrastructure before you act. Photo via ondaka.com

Ondaka isn't your typical Bay Area startup. The company uses an alphabet soup of buzzword technologies — IoT, AI, VR — and allows oil and gas companies to really visualize their infrastructure. The Palo Alto-based startup is a StartX company and a member at Station Houston for its local office.

Dark Vision Technologies Inc.

Canada-based Dark Vision has created a tool that can take ultrasound images of wells. Photo via darkvisiontech.com

North Vancouver, British Columbia-based Dark Vision has spent years developing its ultrasound technology that can get a 360-degree view of oil wells. According to the website, Dark Vision can find a number of downhole issues, such as tubing defects, casing corrosion, obstructions, and more.

Cemvita Factory

The Karimi siblings have created a way to synthetically convert CO2 into glucose, and they are targeting the energy and aerospace industries for their technology. Courtesy of Cemvita Factory

Houston-based Cemvita Factory didn't present its CO2-to-glucose conversion technology at the roundup, but the company's presence earlier in the day was enough for the judges. Co-founder Moji Karimi tells InnovationMap in a previous story about how the technology has many applications in oil and gas, but also in space operations,

Lift Etc.

Even though Lift ETC didn't present in the roundup, the Houston-based company walked away with an award for its artificial lift technology that is more efficient and cheaper for companies to use. According to the website, Lift ETC has a technology that's proven to lower the surface compressor requirements up to 75 percent and increase production.

SensorField

Houston-based SensorField didn't present, but still walked away with recognition from Rice. Photo via sensorfield.com

When it comes to using IoT for remote oilfield site monitoring, Houston-based SensorField is ahead of the curve. The company's device — so small it can fit in the palm of your hand — is powerful enough to provide complete monitoring capabilities from fluid level and pressure to rotating machinery health and location security, according to the website.

Wafik Beydoun has served on the board of OTC for almost a decade. Courtesy of Beydoun

Houston OTC chairman sees an increasing effect of digital tech ahead of the 50th anniversary

Featured Innovator

Wafik Beydoun has been on the board of the Houston Offshore Technology Conference — and has served as chairman for the past two years. As he prepares to pass the baton after this year's event, he's reflected on how much the conference has changed — namely due to new innovation and technologies.

"The rising tide of the digital revolution is lifting us all — not only OTC or the industry — and it's lifting us at an exponential rate," Beydoun tells InnovationMap. "Digital is moving now exponentially, whether we want it to or not, we're benefitting from it."

OTC takes place at NRG Park from May 6 to 9. Beydoun shares his observations and advice on how innovation and startups have effected change at the 50-year-old conference.

InnovationMap: What's going to differentiate this year's conference from previous years?

Wafik Beydoun: This year is very special because we are celebrating the 50th birthday of OTC. The first event was held in May of 1969. Last year it was the 50th event, so these two years are very unique. Last year, we had an opening ceremony, and we will have that again this year — that's different from OTCs in the past.

The most important change you'll see is the amount of papers on offshore renewables — it's something the board wanted to test and show that the industry is being more aware in this area. What I mean when I say offshore renewables is mostly offshore wind, but there's also energy from waves and gas hydrates — another form of gas trapped under ice in the subsea. These are things we have had in the past few years, but this year we have 14 sessions on marine renewables.

IM: What sort of new technologies (machine learning, IOT, AI, etc.) are you excited about seeing grow its presence at OTC?

WB: The way the technologies are impacting is it can go from drilling to monitoring remotely. More and more platforms in difficult conditions are reducing the number of people involved. There are already talks about unmanned platforms offshore. On safety in general, digital and AI immersion are able to help train people faster and without injuring themselves.

IM: How have startups been represented at the conference?

WB: We recognize that startups are adding a lot of oxygen into OTC. We need that for different reasons. For one, they bring in innovation in energy. Also with this kind of digital area, we have a lot of startups coming from Silicon Valley that want to innovate in the energy domain, and OTC can be that space where we can invite them to help us in our challenges.

IM: How has innovation and technology affected the conference specifically over the years?

WB: The conference is the place where you have all the specialists come and talk about their projects — it attracts all those who have an exciting story to tell, and it could be in innovation. And they bring their tool or technology into the exhibition. In 1969 at OTC, you could see the suit we'd put humans in to go under water. Now, you can see the robots that explore the seafloor.

IM: How has innovation and technology affected the conference specifically over the years?

WB: Register for the Rice Alliance Startup Roundup event. You have the opportunity to invest or meet face-to-face these 50 startups on the rise. The second thing you should attend is the Spotlight on the New Technology Award. Based on these technologies, you can have a feel of what's the leading edge of technology for the industry as presented by exhibitors. If an entrepreneur wants to see what's new and bringing money, attending this will show him or her what companies want that new technology.

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Portions of this interview have been edited.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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