Ayoade Joy Ademuyewo founded Lokum last year to create a solution to better connecting medical specialists with health care facilities nationwide. Photo courtesy of Lokum

Ayoade Joy Ademuyewo says that anesthesiology is “the coolest thing in the world.” That’s why she became a certified registered nurse anesthetist.

And that career, which she says is “the perfect blend of science and art,” led to the creation of her startup, Lokum.

Lokum App is a matchmaking engine that aims to connect Ademuyewo’s peers with jobs. She explains that before her innovation, staffing for nurse anesthetists traditionally owed to job boards 30 years older than she was or to recruitment agencies that left them at a disadvantage.

“I didn't want to use that job board because it was sort of difficult to use and I didn't want to use it and a lot of other people felt the same way,” she recalls.

When a desperate friend asked for her help navigating the terrain of finding CRNA work as an independent contractor, Ademuyewo says the wheels began turning in her mind.

“I just thought, 'Why can't I open up my phone and see all of the available jobs to me, based on my preferences and my skills? And I can easily select from them to go to my next job.' And that's sort of where the questions started. And I just kept asking those questions. And I think about two or three years into asking the questions I was like, 'Oh my gosh, I think I'm starting a company,'” Ademuyewo says.

In the hours that she wasn’t in surgery, the CRNA began doing market research.

“As I was studying the market, and mapping it out, these really complex mind maps started to happen. And it was almost a natural conclusion that the more you understand the problem, the more the solution starts to appear to you,” she explains.

And she saw that the obvious solution was also potentially a big opportunity for her to create something entirely new — neither a job board nor an agency, but something entirely new. Ademuyewo calls Lokum a “matchmaking engine.” It takes the preferences, specialties and skills of CRNAs like her and matches them to jobs that make sense for them. To date, the pilot has connected users with around 200 hospitals and clinics in 20 states.

Fortunately, because there are so few CRNAs in practice, they are a unified bunch.

“It’s a really well-networked profession,” says Ademuyewo. “ I'm lucky to be in a profession where what we do is really special and really specialized.”

Because she was already part of the tight knit community, the founder had no trouble finding pilot customers. She worked with Houston-based Octaria Software to engineer the technical side of the app, as well as another local cybersecurity firm to work on infrastructure.

Lots of big news has come for Ademuyewo in the first half of 2024. She participated in this year’s cohort of the Google for Startups Accelerator Program-North America, which she says helped to gain traction in her fundraising amid a bear market.

The result? Early this month, Lokum announced a raise of $700,000 in pre-seed funding, which will be allocated to improving and enhancing the existing technology. Those funds came from Houston investors including Aileen Allen, of the Houston Angel Network, Mercury, and The Artemis Fund; and Matt Miller, former Liongard product executive, as well as from Houston-based VC firm South Loop Ventures. More came from the non-local JP Morgan and Techstars.

Today, Ademuyewo is devoted full-time to Lokum, though she still practices her favorite combination of science and art on weekends in order to maintain her licensure.

“I will always be clinical, that will never change,” she says. “Part of that is just staying close to the problem and the people who are experiencing it, I think that is exactly the right thing for me to be doing.”

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.