The Alexandria Center for Advanced Technologies at The Woodlands is open for business. Rendering courtesy of Alexandria Real Estate Equities

A new innovation hub mega campus has opened in The Woodlands.

The Alexandria Center for Advanced Technologies at The Woodlands comes courtesy of California-based Alexandria Real Estate Equities Inc. The campus is home to the first purpose-built, cost-effective Class A laboratory infrastructure in the Houston suburb.

The campus takes advantage of Alexandria’s cluster model, which is informed by the cluster theory of business created by Harvard Business School’s Michael E. Porter. The belief behind the cluster is that there are four critical drivers necessary to creating a thriving business cluster: location, innovation, talent and capital. With nearly three decades of creating such STEM ecosystems, Alexandria is well positioned to grow something important in The Woodlands.

The campus’ first building is a 123,392-square-foot, LEED Gold Core and Shell, and Fitwel-certified redevelopment project. One of the initial tenants in that building is Nurix Therapeutics, a San Francisco-based clinical-stage biopharmaceutical company.

“We have had an outstanding strategic relationship with Alexandria since 2014 and approached them to support our expansion to Texas,” Arthur T. Sands, MD, PhD, president and chief executive officer of Nurix said in a press release. “The Woodlands offers us a business-friendly, entrepreneurial environment that is critical to our growth. Alexandria’s thoughtfully designed new campus provides us with state-of-the-art laboratory space and dynamic amenities that are key to helping us attract and retain top talent as we work to change the future of medicine through an exciting new modality of treating disease: targeted protein modulation.”

Nurix’s focus is treating cancer and other challenging diseases using protein modulation. Its expansion to the Houston area will help the company to build both proprietary and partnered programs in oncology as well as autoimmune and inflammatory diseases.

“Our efforts in The Woodlands are much like when we entered New York City, where commercial life science was very limited before we opened our flagship Alexandria Center for Life Science – NYC in 2010,” Joel S. Marcus, executive chairman and founder of Alexandria Real Estate Equities, Inc. and Alexandria Venture Investments, says in a news release. "We are similarly committed to developing a commercial life science presence in The Woodlands.

"Steve Jobs once said, ‘the biggest innovations of the twenty-first century will be at the intersection of biology and technology,’ and his prediction has come to fruition," Marcus continues. "Here in The Woodlands, this important convergence will drive opportunities to accelerate the development of new medicines to benefit patients."

Care for a round of pickleball with a colleague? The Alexandria Center for Advanced Technologies campus is replete with appealing with amenities. They indeed include onsite pickleball courts, but also modern conference and event space; an large, welcoming courtyard and event lawn; and a wellness and fitness center so innovators can keep their bodies as healthy as their minds.

With the objective of further driving this STEM ecosystem, the company is also bringing the Alexandria Seed Capital Platform to The Woodlands. The nationwide platform unites leaders from across the life science community to catalyze early-stage investment in life science companies. If Alexandria’s goals come to fruition, more medical companies may soon be heading to Houston’s ‘burbs.

The Alexandria Center for Advanced Technologies at The Woodlands

Image courtesy of Alexandria Real Estate Equities

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Houston researchers develop breakthrough device that could bypass spinal injuries

breakthrough research

Scientists at Houston Methodist have announced a significant leap forward for spinal cord injury recovery.

The researchers have developed a device that essentially bypasses spinal injuries, allowing signals from previously “lost” functions to reach the brain, a new study published in Nature Communications shows.

“Most current technologies try to improve whatever function remains after a spinal cord injury,” Dr. Damiano Barone, assistant professor of neurosurgery in the Department of Neurosurgery at Houston Methodist and co-lead on the study, said in a news release. “Our goal is different. Rather than fixing the injury itself, we want to bypass it completely and create an alternative route for signals to travel.”

The study involved a single ultrathin circumferential electrode array made to conform around the spinal cord without penetrating neural tissue, which was implanted into rodent and pig models with spinal injuries. The electrode array was able to interpret motor, sensory and autonomic signals around the injury. Think of it as a set of detours that restore road access to isolated towns after a disaster destroys the highway instead of just rebuilding the highway.

Over the course of three days, the arrays detected signals of intended movement from low-frequency spinal oscillations with more than 94 percent accuracy. This worked across species and was replicated in feasibility studies on human cadavers.

This research could serve as a new foundation for neuroprosthetic implants that could restore connectivity to the 2.5 million people worldwide suffering from spinal injuries that result in loss of ability. Future development could result in everything from restored organ function to mobility, according to Houston Methodist.

George Malliaras, the Prince Professor of Technology in the Department of Engineering at the University of Cambridge, who co-led the study, sees it as a fundamental restructuring of the science of spinal trauma.

“This could represent a paradigm change in how we think about spinal cord injuries,” Malliaras said. “Instead of starting from the idea that what is lost is gone forever, this approach asks whether we can restore function by carrying the signal around the injury.”

Further work involving laboratory models will need to be completed before launching human trials.

Grants from the National Institutes of Health, Houston Methodist Katz Investigator Award, Helaers Research Award and the Engineering and Physical Sciences Research Council helped support the study. Other collaborators on the study include Salim Hadwe, Ruben Serrano, George Psaltakis, Margaux Forner, Chaeyeon Lee, Sydney Swedick, Moleca Ghnnam, Tawfique Hasan and Alejandro Carnicer-Lombarte from the University of Cambridge; and Anton Banta and Xueer Zhang from Houston Methodist.

Abbott assembles expert team to help lure U.S. Space Academy to Texas

space race

State Rep. Greg Bonnen of Friendswood has been tapped to lead a new team that will promote Texas as the future home of the U.S. Space Academy.

Bonnen, a neurosurgeon, chairs Houston Physicians’ Hospital and the powerful Texas House Appropriations Committee. His House district is close to NASA’s Johnson Space Center.

Gov. Greg Abbott appointed the seven-member team. Last month, President Trump signed an executive order establishing the Presidential Commission on the U.S. Space Academy. Commission members, who held their first meeting this month, will recommend a permanent location for the academy.

Texas officials are pushing a site near Johnson Space Center to host the academy. Alabama, Colorado and Florida are among Texas’ competitors.

In a joint statement, U.S. Sen. Ted Cruz and U.S. Rep. Brian Babin, both of Texas, issued a statement backing the state’s bid for the academy. Cruz lives in Houston. Babbin lives in Woodville, about 55 miles south of Beaumont.

“America’s space program is built across the country, but Texas is where the pieces come together,” the lawmakers said. “We are ready to lead the next generation of space pioneers and look forward to showing why Texas is the right home for the U.S. Space Academy.”

The academy’s curriculum will include technical education, leadership development and public service components. Graduates will be set up for careers in the U.S. military, civil service, and aerospace sectors.

The Abbott-appointed team will work with the Texas Space Commission to prepare the state’s proposal for the academy.

In addition to Bonnen, team members with ties to Houston include:

  • Robert Ambrose, who grew up in Houston. He worked at Johnson Space Center before becoming associate director of the Texas A&M Space Institute.
  • Former NASA astronaut Nancy Curry-Gregg, director of the Texas A&M Space Institute. She earned a doctoral degree from the University of Houston and previously worked at Johnson Space Center.
  • Former NASA astronaut Jack Fischer, senior vice president of Houston-based Intuitive Machines. The company builds spacecraft, delivers payloads to the moon and launches satellites.

“Texas is the home of America’s human spaceflight program,” Abbott said in a release. “No state can match what Texas brings to this mission.”

“NASA’s Johnson Space Center, world-class universities, a premier commercial space industry, major military installations, and an unmatched aerospace workforce give Texas every asset the United States Space Academy requires,” the governor added.