The show had to go on at the annual Energy Tech Venture Day, which was put on virtually by the Rice Alliance on May 7. Zukiman Mohamad/Pexels

Rice Alliance for Technology and Entrepreneurship's annual Energy Tech Venture Day is usually hosted as a part of the Offshore Technology Conference that takes over NRG Center each May. However, when OTC announced its cancelation, Rice Alliance made sure the show would go on.

"We had many startups and corporations reach out to us and ask us if we could go ahead with the event in a virtual format, so that's how we ended up where we are today," says Brad Burke, managing director of the Rice Alliance at the start of the event.

Throughout the two-hour pitch event, 39 startups pitched their companies in two minutes and 30 seconds or less. The companies were selected based on input from the alliance's energy advisory board. The companies, Burke says, represent innovations across the energy industry.

An additional 24 companies participated in virtual office hours with investors through a speed-networking process.

"We know that the needs of startups to raise capital, to find customers, and to find pilots is even greater today than it was several months ago," Burke says. "And we know that the needs of energy companies to find innovative technologies to reduce costs and increase production are even greater as well."

Usually at this event, the advisory board decides on the 10 most promising energy tech startups, however, this list will not be revealed this year.

Of the startups that pitched that represented 11 different states and six different countries, 13 call Houston their HQ. Here's what local startups pitched.

Bluware

Bluware's E&P clients use the startup's cloud computing and deep learning technology to access seismic data. This data is crucial for geoscientists to make faster and smarter decisions to reduce time to oil. Bluware's headquarters is in West Houston, and has an European office in Norway.

DAMorphe

Southwest Houston-based DAMorphe uses nanotechnology to provide solutions within oil and gas — among other sectors, including life sciences, consumer goods, and more. Within O&G specifically, the company has designed dissolvable frac plugs and balls with superior performance and lower cost, as well as a flowable sensor for downhole measurements.

dataVediK

Early-stage Houston startup dataVediK focusing on enterprise digital transformation with a plan to create an artificial intelligence platform for collaboration between data scientists and domain experts to provide tech solutions for oil and gas — such as optimizing operations costs and productivity, enhancing safety, and more.

DelfinSia

Houston-based Delfin specializes in text analytics and is working with two oil supermajors. Sia, Delfin's product, is a virtual adviser, able to reference a client's unstructured data in real-time to ensure that decisions are fully informed. Users can simply ask Sia a question and get the best answers from company data.

Flutura Decision Sciences and Analytics

Flutura's motto is to promote actions — not just insights with data. The company's main product is Cerebra uses artificial intelligence and industrial internet of things to connect the dots within the oil and gas supply chain. Flutura's clients include Shell, Honeywell, Henkel, TechnipFMC, Patterson UTI, ABB, BJ Services, Daimler Benz, and more.

MyPass Global

A workforce management system, MyPass Global is putting the power of data into the hands of the individual workers at oil and gas companies and is creating digital work skills passport for each employee. The startup has developed a network of over 180 business partners across Australia, New Zealand, and the United States, which includes more than 27,000 registered workers.

Nomad Proppant Services

For E&P companies, Nomad is revolutionizing the way sand is delivered and used by wells. The average well uses 10,000 tons of sand, and that means trucking that volume via long hauls. However, Nomad has created a new, mobile mine that can save 25 percent of the company's spend on sand.

Osperity

Houston-based Osperity's technology provides AI-driven intelligent visual monitoring for industrial operations that can result in improved safety, reduced carbon footprints, and more. The company has more than 40 industrial customers using its monitoring services. Osperity offices in the Galleria area and has a location in Calgary.

PhDsoft Technology

PhDsoft, an engineering technology company, has created a technology specializing in industrial digital twins. The company's 4D software, PhDC4D®, can predict the effect of time and elements on equipment and facilities, which can save its industrial clients money and downtime of its machinery, as well as improve safety conditions.

Quidnet Energy

Clean energy tech company, Quidnet Energy, is providing electricity storage solutions that are cost effective and are able to be used long term. Quidnet uses traditional pumped hydro storage that, before the company, was restricted to specific terrains. The company offices out of downtown Houston.

SOTAOG

Data analytics company SOTAOG wants to be one-stop shop for its energy clients' data needs. SOTAOG's proprietary algorithms can provide real-time data that can improve operations and create cost-saving initiatives. The company works out of The Cannon's West Houston campus.

Voyager

Houston-based software startup Voyager is making waves in the maritime bulk-shipping industry. Whether shipping plans are transporting crude oil and LNG or complex offshore rig movements, Voyager can replace the thousands of logistics emails shared across several companies and bring communications and data onto one platform. The company's main office is in downtown Houston, but also has an office in Brazil.

WellNoz

WellNoz creates inflow control devices, or ICDs, for its oil and gas industry clients. The downhole devices are crucial for controlling the opening and closing of the well. WellNoz's device is made from a proprietary metal alloy that remains strong to remain closed when required, and then dissolves after a certain time to open up the valve. The startup's first client is Abu Dhabi National Oil Company, which will will purchase 10,000 ICDs each year for the next five years.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”