New delivery service speeds into Houston

There's an app for that

GoPuff is a combination of concierge service and errand runner. Photo courtesy of goPuff

Everyone knows how hard it is to manage to get everything done in a single 24-hour period. Errands to run, groceries to pick up, food to buy, prescriptions to get. To-do lists seem never-ending, and for busy professionals, can be absolutely overwhelming.

Enter goPuff, a Philadelphia-based retailer that has just launched in the Bayou City. Think of it as a combination of concierge service and errand runner. The company stocks more than 2,500 products across eight categories. Those items, ranging from snacks to beverages to household essentials to pet needs, are housed in centrally located facilities in Houston.

When customers need something, they log into their goPuff account, select what they want, and the company's delivery drivers bring it straight to their door. Delivery hours are from noon to 4:30 am, seven days a week, with a flat delivery charge of $1.95.

Founded in 2013, goPuff is now available in more than 90 cities, including Atlanta, Boston, Chicago, Dallas, Denver, Philadelphia, Phoenix, Seattle, Pittsburgh, and Washington, D.C. "Customers have been asking us to come to Houston since we first launched the concept, and we are thrilled to now bring that experience to the area and deliver the moments that matter most to this vibrant community," said Rafael Ilishayev, goPuff co-founder and co-CEO, in a statement announcing the expansion to Houston.

In Houston, the company will cover the enormity of the city, from the Texas Medical Center to Northeast Houston, Independence Heights to the Fifth Ward. Customers will place their orders on the goPuff app, the same way they would for other delivery services. Then, goPuff team members head out, collect what's needed, and deliver it.

The company touts its speed of delivery as a main selling feature; because the products are housed at goPuff facilities, drivers don't need to head all over town to collect needed items, and there are no third parties to work with. But what about cold treats like ice cream?

"Because we warehouse product inventory at our own facilities, we can quickly pack orders in our special insulated bins and pass them off to our driver partners for fast deliveries, keeping the ice cream cold," Liz Romaine of goPuff tells CultureMap.

Given the furious speed at which live in the Bayou City moves, goPuff should find a pretty warm welcome here in Houston.

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This story originally appeared on CultureMap.com.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”