Photos: WeWork opens 4th Houston location in Hines downtown trophy tower and plans expansion in the Galleria

Coworking it out

WeWork opened the doors to its fourth Houston location. Courtesy of WeWork

WeWork has officially doubled down on its downtown presence in Houston. The coworking company has officially opened the doors of its space within Hines' trophy tower.

The coworking space makes up 50,000 square feet on two floors of 609 Main St. The 48-story building, which is owned and developed by Houston-based Hines, premiered on the downtown Houston skyline in 2017.

"The new WeWork space at 609 Main Street is a great complement to our state-of-the-art office building in downtown Houston," says Philip Croker, senior managing director at Hines, in a news release. "It's been a pleasure to work with this team and we are eager to see their space filled with Houston's cutting-edge businesses. We know WeWork in Houston is strong and look forward to our partnership growing in the years to come."

Meanwhile in the Galleria area, WeWork is opening two additional floors of its space in Galleria Tower I this month. More details on the expansion are still to come.

The new 609 Main location, which was originally announced this summer, joins the Galleria location and a Woodlands location in Hughes Landing, which also just announced its new location recently, as well as another downtown location in the Jones Building — just across the street at 708 Main St.

The new location is modern and high-end, per the release, which juxtaposes its historic sister location in downtown. The 609 Main location has a more executive feel than the homey environment of the Jones Building. For that, the new location charges a bit of a premium. Private offices at 609 Main begin at $780 a month, compared to the rates of $550 at the Jones Building and $580 at Galleria Tower I. Unassigned desk memberships are around $300 monthly for the two older locations, compared to closer to $400 for 609 Main.

"WeWork is eager to continue its expansion in the Houston area with the opening of our fourth location in Houston and second downtown," says Nathan Lenahan, general manager for Texas at WeWork, in the release. "The space at 609 Main Street is a perfect location for those businesses and entrepreneurs downtown looking to expand and have a flexible, creative office environment that promotes community."

Last month, the New York Times announced job cuts companywide for WeWork, however there has not been any regional reports for the coworking company or any information on how the cuts will affect Houston locations.

Executive feel

wework 609 main

Courtesy of WeWork

Compared to WeWork's other Houston locations, the 609 Main space has more of an executive feel — and monthly membership reflects that. Rates are a full $200 more a month for a private office compared to WeWork's other downtown location.

It's WeWork Labs' second Texas location — the first opened last fall in Dallas. Courtesy of WeWork

WeWork brings early-stage startup program to downtown Houston

lab work

WeWork is betting on the Bayou City as it plans to open up WeWork Labs in its downtown Houston coworking space. The early-stage program will provide up to 30 startups with mentorship and resources coordinated by its partner organization, Alice, an entrepreneurial digital resource with Texas ties.

"At Alice, our research has shown that entrepreneurs are hungry for guidance that gets into the nitty gritty: 'What next step should I take?' 'How exactly do I go about fundraising?' 'What should my to-do list look like if customer acquisition is my No. 1 goal?'' says Carolyn Rodz, CEO and co-founder of Alice, in a release. "We're really excited to collaborate with WeWork Labs to bring these answers to their members through both programming and online support."

WeWork Labs launches this month in the WeWork Jones Building at 708 Main St. It's the second Texas location — Dallas' location opened last fall. Prices for the program begin at $300 a month for entrepreneurs, and the program does not take equity in the participating startups.

Leading the program is Labs Manager Carlos Estrada and WeWork Managing Director Emily Keeton — both have long careers in innovation and startups across the country. Keeton was among the original founders of Station Houston and is based in Houston. A Houston native, Estrada most recently launched Roots Venture Group, which focused on growing startups within the agricultural and rural industries.

"As the fourth largest city, Houston is in a unique position to launch high-impact startups," Estrada says in the release. "We see WeWork Labs in Houston as a tremendous platform for innovation, as our founder-focused approach to supporting early-stage startups will nurture and accelerate the work of entrepreneurs to scale their solutions to today's biggest challenges. We look forward to growing our community here and bringing together key players across the region to drive innovation throughout Houston, the state of Texas, and beyond."

WeWork Labs launched around a year ago and now has over 30 locations worldwide. The program hopes to connect the dots for startups and the corporate world by providing education, mentorship, and a global network. The downtown Houston location will operate alongside WeWork's Veterans in Residence program and the Flatiron School campus.

"We are incredibly honored to have WeWork Labs join our community to support an already growing network of startups within the city of Houston," says Nathan Lenahan, WeWork's general manager for Texas, in the release. "Housing WeWork Labs with both our Flatiron School campus and Veterans in Residence program is a true testament to the innovative community we strive to create within our spaces. We are thrilled to expand on our commitment to Houston and its entrepreneurs and can't wait to see the impact we can have together on it's diverse community."

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Houston researchers develop material to boost AI speed and cut energy use

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A team of researchers at the University of Houston has developed an innovative thin-film material that they believe will make AI devices faster and more energy efficient.

AI data centers consume massive amounts of electricity and use large cooling systems to operate, adding a strain on overall energy consumption.

“AI has made our energy needs explode,” Alamgir Karim, Dow Chair and Welch Foundation Professor at the William A. Brookshire Department of Chemical and Biomolecular Engineering at UH, explained in a news release. “Many AI data centers employ vast cooling systems that consume large amounts of electricity to keep the thousands of servers with integrated circuit chips running optimally at low temperatures to maintain high data processing speed, have shorter response time and extend chip lifetime.”

In a report recently published in ACS Nano, Karim and a team of researchers introduced a specialized two-dimensional thin film dielectric, or electric insulator. The film, which does not store electricity, could be used to replace traditional, heat-generating components in integrated circuit chips, which are essential hardware powering AI.

The thinner film material aims to reduce the significant energy cost and heat produced by the high-performance computing necessary for AI.

Karim and his former doctoral student, Maninderjeet Singh, used Nobel prize-winning organic framework materials to develop the film. Singh, now a postdoctoral researcher at Columbia University, developed the materials during his doctoral training at UH, along with Devin Shaffer, a UH professor of civil engineering, and doctoral student Erin Schroeder.

Their study shows that dielectrics with high permittivity (high-k) store more electrical energy and dissipate more energy as heat than those with low-k materials. Karim focused on low-k materials made from light elements, like carbon, that would allow chips to run cooler and faster.

The team then created new materials with carbon and other light elements, forming covalently bonded sheetlike films with highly porous crystalline structures using a process known as synthetic interfacial polymerization. Then they studied their electronic properties and applications in devices.

According to the report, the film was suitable for high-voltage, high-power devices while maintaining thermal stability at elevated operating temperatures.

“These next-generation materials are expected to boost the performance of AI and conventional electronics devices significantly,” Singh added in the release.

Houston to become 'global leader in brain health' and more innovation news

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Editor's note: The most-read Houston innovation news this month is centered around brain health, from the launch of Project Metis to Rice''s new Amyloid Mechanism and Disease Center. Here are the five most popular InnovationMap stories from December 1-15, 2025:

1. Houston institutions launch Project Metis to position region as global leader in brain health

The Rice Brain Institute, UTMB's Moody Brain Health Institute and Memorial Hermann’s comprehensive neurology care department will lead Project Metis. Photo via Unsplash.

Leaders in Houston's health care and innovation sectors have joined the Center for Houston’s Future to launch an initiative that aims to make the Greater Houston Area "the global leader of brain health." The multi-year Project Metis, named after the Greek goddess of wisdom and deep thought, will be led by the newly formed Rice Brain Institute, The University of Texas Medical Branch's Moody Brain Health Institute and Memorial Hermann’s comprehensive neurology care department. The initiative comes on the heels of Texas voters overwhelmingly approving a ballot measure to launch the $3 billion, state-funded Dementia Prevention and Research Institute of Texas (DPRIT). Continue reading.

2.Rice University researchers unveil new model that could sharpen MRI scans

New findings from a team of Rice University researchers could enhance MRI clarity. Photo via Unsplash.

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI. In a study published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Continue reading.

3. Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

The new Amyloid Mechanism and Disease Center will serve as the neuroscience branch of Rice’s Brain Institute. Photo via Unsplash.

Rice University has launched its new Amyloid Mechanism and Disease Center, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases. The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established. Continue reading.

4. Baylor center receives $10M NIH grant to continue rare disease research

BCM's Center for Precision Medicine Models has received funding that will allow it to study more complex diseases. Photo via Getty Images

Baylor College of Medicine’s Center for Precision Medicine Models has received a $10 million, five-year grant from the National Institutes of Health that will allow it to continue its work studying rare genetic diseases. The Center for Precision Medicine Models creates customized cell, fly and mouse models that mimic specific genetic variations found in patients, helping scientists to better understand how genetic changes cause disease and explore potential treatments. Continue reading.

5. Luxury transportation startup connects Houston with Austin and San Antonio

Shutto is a new option for Houston commuters. Photo courtesy of Shutto

Houston business and leisure travelers have a luxe new way to hop between Texas cities. Transportation startup Shutto has launched luxury van service connecting San Antonio, Austin, and Houston, offering travelers a comfortable alternative to flying or long-haul rideshare. Continue reading.

Texas falls to bottom of national list for AI-related job openings

jobs report

For all the hoopla over AI in the American workforce, Texas’ share of AI-related job openings falls short of every state except Pennsylvania and Florida.

A study by Unit4, a provider of cloud-based enterprise resource planning (ERP) software for businesses, puts Texas at No. 49 among the states with the highest share of AI-focused jobs. Just 9.39 percent of Texas job postings examined by Unit4 mentioned AI.

Behind Texas are No. 49 Pennsylvania (9.24 percent of jobs related to AI) and No. 50 Florida (9.04 percent). One spot ahead of Texas, at No. 47, is California (9.56 percent).

Unit4 notes that Texas’ and Florida’s low rankings show “AI hiring concentration isn’t necessarily tied to population size or GDP.”

“For years, California, Texas, and New York dominated tech hiring, but that’s changing fast. High living costs, remote work culture, and the democratization of AI tools mean smaller states can now compete,” Unit4 spokesperson Mark Baars said in a release.

The No. 1 state is Wyoming, where 20.38 percent of job openings were related to AI. The Cowboy State was followed by Vermont at No. 2 (20.34 percent) and Rhode Island at No. 3 (19.74 percent).

“A company in Wyoming can hire an AI engineer from anywhere, and startups in Vermont can build powerful AI systems without being based in Silicon Valley,” Baars added.

The study analyzed LinkedIn job postings across all 50 states to determine which ones were leading in AI employment. Unit4 came up with percentages by dividing the total number of job postings in a state by the total number of AI-related job postings.

Experts suggest that while states like Texas, California and Florida “have a vast number of total job postings, the sheer volume of non-AI jobs dilutes their AI concentration ratio,” according to Unit4. “Moreover, many major tech firms headquartered in California are outsourcing AI roles to smaller, more affordable markets, creating a redistribution of AI employment opportunities.”

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