Beyoncé's dad is teaching a must-attend music business class. Photo courtesy of Mathew Knowles

Ever notice how Beyoncé's hair magically flows as if a fan follows her around everywhere she goes? That's not an accident. That attention to image micro-detail is preached by her father, Mathew Knowles, who created Destiny's Child and Music World Entertainment, the label and production company that boasts two of the top-selling superstars of the previous decade.

Now, music mogul Knowles is sharing his considerable knowledge in a new, 15-week virtual master class at the University of Houston's C.T. Bauer College of Business, running from January 25, 2021 to May 10, 2021. Knowles teases that there will be star-caliber guest instructors and appearances. The $3,000 virtual class is limited to 35 students but open to all who are able to register. (UH students and recent alumni can pay a discounted rate of $1,000.)

"I want to change the way we do things in the music business," Knowles says on a Zoom call. "Unfortunately, we have a very high failure rate [in the music industry]. Part of the reason we have this much failure is the business acumen of the team around the artists. It's not their talent. It's their team."

He hopes to change that with the class, dubbed "The Music Industry and the Digital Age." The class isn't specifically for aspiring artists, but aimed at those "behind the microphone," says Knowles. "Some people will be managers. Others will be independent record labels. Others will be in marketing. Artists will be part of this that would like to know business side of this."

Knowles is one of Houston's great success stories. Once a successful executive at Xerox, he recognized that his daughter, Beyoncé, had extraordinary music talent. He created Destiny's Child, held what he called "music bootcamps" at his home, and took night classes in entertainment management at Houston Community College.

From there, he founded his Music World Entertainment empire in 1992 in a Third Ward house, which mirrored his faraway mentor, Quincy Jones, who ensured every aspect of Motown's operation was all under one roof. Knowles would then become one of the most respected business minds in the music industry; he's taught at Texas Southern University; scored a PhD, and crafted management degrees for other schools. His empire boasts more than 100 award-winning albums and an MTV Video Music Award.

But that success, knowledge, and experience came with trial, error, and considerable money lost. "I wish someone had told me, 'Look, you need to really focus on getting the business acumens of the music industry down,'" he says.

That said, even with Destiny's dad's name attached, students shouldn't expect a get-famous-quick lottery ticket path to success with this class. "They think they can go from zero to a hero," Knowles says of that mindset. "This is not a microwave industry. I always say there is a price of admission to the music industry."

Sign us up. Memo to Professor Knowles: May we request guest lectures by Houston royalty Queen Bey and Lizzo?

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This article originally ran on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.