Houston needs to lighten up a little, sheesh. Photo by Rome Wilkerson on Unsplash

Not-so-happy news for Texans living in Houston – they're living in one of the "unhappiest" cities in the nation.

A recent SmartAsset study ranked Houston the No. 81 happiest city in the U.S., based on an analysis of 90 large cities for their residents' quality of life, well being, and personal finances.

The city's rank in the bottom 10 — alongside Texas neighbors Dallas (No. 80), El Paso (No. 83), and Laredo (No. 89) – shows not everything about Houston is as easygoing as people think it is. We can hear Ken Hoffman's disagreement from here.

The study found 28.5 percent of all Houston households make a six-figure salary or more, and 16.2 percent of residents are burdened by their housing costs. Houston's poverty rate is 20.7 percent, so maybe it really is more difficult to live comfortably in the city, after all.

Houston has a marriage rate of 39.4 percent, and its residents have a life expectancy of 79 years old. Nearly 76 percent of residents have health insurance, and a Houstonian has nearly five "mentally unhealthy" days per month on average.

Our beloved city has had some bad press recently: H-Town isn't exactly revered for having the best drivers; the city and its suburbs are apparently less appealing for new residents making the move to Texas; and its popularity in the tech industry seems to be waning.

It's not all doom and gloom, though. There's always plenty of new restaurants to try, our city's inventive art scene remains unmatched, and plenty of hometown hero celebrities, Hall of Fame athletes, and talented musicians praise Houston for its culture and hospitality.

While money can't necessarily buy happiness, SmartAsset suggests that having a higher quality of life can influence a person's financial decisions, therefore leading to a greater probability of beneficial outcomes. Of course, that's assuming high financial literacy and strong money management skills.

"Depending where you live, certain quality of life factors, including metrics like life expectancy, infrastructure and the rate of marriage, can ultimately impact your happiness," the report's author wrote.

Elsewhere in Texas, the Dallas suburb of Plano soared to the top as the No. 2 happiest city in the nation. More than half (52.5 percent) of all Plano households make a six-figure salary or more, and only 12.1 percent of residents are burdened by their housing costs. Plano's poverty rate is less than five percent, its marriage rate is 56 percent, and nearly 90 percent of Plano residents have health insurance.

Other Texas cities that earned spots in the report, that notably aren't as happy as Plano, include: Fort Worth (No. 38), Arlington (No. 47), Irving (No. 64), Austin (No. 65), San Antonio (No. 70), Corpus Christi (No. 77), and Lubbock (No. 78).

The top 10 happiest cities in the U.S. are:

  • No. 1 – Arlington, Virginia
  • No. 2 – Plano, Texas
  • No. 3 – Fremont, California
  • No. 4 – San Jose, California
  • No. 5 – Seattle, Washington
  • No. 6 – Boise City, Idaho
  • No. 7 – Raleigh, North Carolina
  • No. 8 – Chesapeake, Virginia
  • No. 9 – San Francisco, California
  • No. 10 – Anchorage, Alaska
The report ranked the 90 most populous U.S. cities based on data from the U.S. Census Bureau 1-Year American Community Survey for 2022 and from the County Health Rankings and Roadmaps for 2023. Data that factored into each city's ranking included a city's household income, poverty level, life expectancy, health insurance rates, marriage rates, overcrowding rates, and more.The full report and its methodology can be found on smartasset.com

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This article originally ran on CultureMap.

A Houston innovator has created a video game that teaches users money fundamentals. Image via eyf.money

Houston startup launches gamified financial education tool

let's play

The fact that the average American would struggle to cover a $400 emergency expense is a sign that there’s a dire need for a better understanding of financial literacy in this country.

But where is the proper starting point? What is the best age to start learning about debt, credit, inflation, loans, stocks, index funds, and personal finance?

According to Grant Watkins, founder of Earn Your Freedom, or EYF, and the startup’s new educational video game, Money Quest, the best time for people to start learning the basics of personal finance and economics is when they’re young.

“I stress to kids that the biggest advantage they have right now is their youth,” says former salesman turned entrepreneur Watkins. “If nothing else, I want kids to play our game to learn the value of compound interest. They’re young, so they should start early, plan early, be strategic, and have fun, life isn’t just all work. But the more you invest early, the more you’re going to have later.”

After realizing that it was best to teach solid financial principles to young people, it was a no-brainer to reach the conclusion that the best way for them to learn was via an educational video game.

That’s where Money Quest comes in.

The innovative and interactive web and mobile video game, which officially launched this month to celebrate Financial Literacy Month, was designed to help kids build a strong foundation in money management, economics and investment in a fun and engaging way. It features challenges and real-world scenarios such as renting a first apartment, opening a first bank account, budgeting at the grocery store, buying stocks and index funds and renting or buying real estate.

All of this is set up in the game’s imaginary city called Prosperity Point.

But before Watkins was able to get to his own Prosperity Point, he was in dire straits financially himself.

At only 27 years old, the native of Katy, Texas, and graduate of Oral Roberts University, found himself trying to get his own personal finances in order three or four years ago and quickly realized that had he been taught how to be an adult and all of the different financial obligations that come with that, it could have saved him from racking up thousands of dollars in debt and making other costly financial mistakes.

“After diving into it, I said, ‘Well, this is a pain, but I bet whoever solves this problem, it would be pretty great for them and everyone else in society,’” says Watkins, who lived in Beijing, China and worked in contract sales, before moving back to the United States. “So, I started working on this idea for Money Quest with the central focus on how I could make financial literacy more engaging?”

With the thread of an idea, Watkins joined Houston’s startup community in August 2021 and began to pull at it and after a prompt from Gamification Advisor Cal Miller, began learning how to code so he could build out his educational video game.

“After getting to the point where it was apparent that I couldn’t afford to get someone else to do it, I rolled up my sleeves and started teaching myself how to code,” says Watkins. “I learned it from free resources like Free Code Camp and Code Academy and we started building it in this specific programming language that we built this game in and just started from scratch.

“We went from one little house, to building an 8-bit character, to building out a road, to now it’s grown into a full-fledged city, with banks and grocery stores and cafes.”

For Watkins, half of his job is building the game and the other half is learning how to be better at building it.

When it came time to market Money Quest, he turned to CMO Keely McEnery, a 22-year-old student at the University of Houston’s Wolff Center for Entrepreneurship.

“Grant is a very smart, driven person, so I’m happy to be on this team, we complement each other very well,” says McEnery. “Money Quest is still a work in progress, it has come a long way since the beginning. Moving forward, we are going to be adding content to the game on a monthly basis and always creating more value.”

The partnership between Watkins and McEnery came at the right time because Texas has started passing laws like Texas Senate Bill 1063, which requires a semester of financial literacy in schools.

“Before COVID-19, there were only three states that had any sort of financial literacy requirements,” says Watkins. “But now, post-COVID, there’s 17 states that have already passed or are in the process of passing financial literacy bills.”

To that end, EYF is working diligently to make sure Money Quest meets the requirements of school curriculums across the country.

“All the studies coming out right now about gaming and education are overwhelmingly positive,” says McEnery. “With things like higher retention rates through gaming education. In fact, it’s dramatically higher.”

In addition to working with the Texas Education Agency and school districts like HISD all over the state of Texas, Watkins and team are working with banks that want to connect with their local high schools and middle schools to talk about financial literacy.

“We’re that perfect partner to connect with those schools and banks,” says Watkins. “They need to work with us because of Community Reinvestment Act (CRA) credits and it makes it a lot easier to connect with their local communities using us instead of just using pamphlets.”

As Watkins continues to bring Money Quest to the masses, he’s experimenting with creative ways for supporters of the game to get involved such as purchasing special NPC’s.

But as EYF builds its game’s brand recognition and begins to proliferate school curriculums, Watkins remains steadfast in his original goal to empower the next generation with the knowledge and skills to achieve financial freedom, which is the best kind of freedom as far as he’s concerned.

“At the end of the day, I want kids to learn to use money wisely, and not blow all their money in their 20s and get into high debt,” says Watkins. “I want to see them learn to be very strategic with their money from the beginning because not doing so will have repercussions down the line.

“I want to instill in them the importance of financial responsibility, smart money management, and economic literacy, so they can build a better financial future for themselves and their communities.”

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."